850557 | RGA-C11

resorcinarene-based amphiphile-C11


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RGA-C11

RGA-C11

resorcinarene-based amphiphile-C11

This mild glucoside detergent can be used as an alternative to GDN, digitonin and CHAPS. Due to the formation of small protein-detergent complexes (PDCs) with GPCRs, along with its enhanced stabilizing effect, this detergent is favorable for protein structural determination, particularly for CryoEM-based structural study. 

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C132H216O56

Percent Composition

C 58.74%, H 8.07%, O 33.20%

Stability
1 Year
Storage Temperature
-20°C
CAS Number
2390023-16-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
2699.090
Exact Mass
2697.410

Hazrat, H., et. al. (2017) Resorcinarene-Based Facial Glycosides: Implication of Detergent Flexibility on Membrane-Protein Stability. Chem. Eur. 23:6724-6729. DOI:10.1002/chem.201605016