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MEGA-10 | 850542

N-decanoyl-N-methylglucamine

850542P

Powder

850542P-
1g
$65.00

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Acyl-N-methylglucamide (MEGA) detergents are non-ionic detergents that provide a good starting point for your structural biology work. The hydrophilic head groups offer ample strength to extract proteins while still providing the capability to stabilize proteins in solution and promote crystal growth.
Molecular Formula
C17H35NO6
Percent Composition
C 58.43%, H 10.09%, N 4.01%, O 27.47%
Purity
>99%
Stability
1 Years
Storage
-20°C
CAS Number
85261-20-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
349.463
Exact Mass
349.246
CMC
~6-7mM
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Chuang, J.H., Y.J. Kao, N.B. Ruderman, L.C. Tung, and Y. Lin. (2011). Optimal concentrations of N-decanoyl-N-methylglucamine and sodium dodecyl sulfate allow the extraction and analysis of membrane proteins. Anal Biochem 418:298-300. [PubMed]Churchward, M.A., R.H. Butt, J.C. Lang, K.K. Hsu, and J.R. Coorssen. (2005). Enhanced detergent extraction for analysis of membrane proteomes by two-dimensional gel electrophoresis. Proteome Sci 3:5 [PubMed]Hierrezuelo, J.M., J. Aguiar, and C.C. Ruiz. (2004). Stability, interaction, size, and microenvironmental properties of mixed micelles of decanoyl-N-methylglucamide and sodium dodecyl sulfate. Langmuir 20:10419-26. [PubMed]Hanatani, M., K. Nishifuji, M. Futai, and T. Tsuchiya. (1984). Solubilization and reconstitution of membrane proteins of Escherichia coli using alkanoyl-N-methylglucamides. J Biochem 95:1349-53. [PubMed]Hildreth, J.E. (1982). N-D-Gluco-N-methylalkanamide compounds, a new class of non-ionic detergents for membrane biochemistry. Biochem J 207:363-6. [PubMed]