850531 | 7.8 MAG

1-(7Z-pentadecenoyl)-rac-glycerol


Oil

Size SKU Packaging Price
1g 850531O-1g 850531O-1g 10 x 100mg $1,900.00
25mg 850531O-25mg 850531O-25mg 1 x 25mg $152.00
200mg 850531O-200mg 850531O-200mg 2 x 100mg $500.00
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7.8 MAG

7.8 MAG

1-(7Z-pentadecenoyl)-rac-glycerol

This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C18H34O4
Percent Composition
C 68.75%, H 10.90%, O 20.35%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1309764-71-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
314.460
Exact Mass
314.246
Johner, N., S. Mondal, G. Morra, M. Caffrey, H. Weinstein, and G. Khelashvili. (2014). Protein and Lipid Interactions Driving Molecular Mechanisms of in meso Crystallization. J Am Chem Soc [PubMed] Caffrey, M. and C. Porter. (2010). Crystallizing membrane proteins for structure determination using lipidic mesophases. J Vis Exp 2010 Nov 21;(45). pii: 1712. doi: 10.3791/1712. [PubMed] Caffrey, M. and V. Cherezov. (2009). Crystallizing membrane proteins using lipidic mesophases. Nat Protoc 4:706-31. [PubMed] Hofer, N., D. Aragao, and M. Caffrey. (2010). Crystallizing transmembrane peptides in lipidic mesophases. Biophys J 99:L23-5. [PubMed] Misquitta, L.V., Y. Misquitta, V. Cherezov, O. Slattery, J.M. Mohan, D. Hart, M. Zhalnina, W.A. Cramer, and M. Caffrey. (2004). Membrane protein crystallization in lipidic mesophases with tailored bilayers. Structure 12:2113-24. [PubMed]