850530 | 7.7 MAG

1-(7Z-tetradecenoyl)-rac-glycerol


Oil

Size SKU Packaging Price
200mg 850530O-200mg 850530O-200mg 2 x 100mg $500.00
500mg 850530O-500mg 850530O-500mg 5 x 100mg $1,080.00
1g 850530O-1g 850530O-1g 10 x 100mg $1,900.00
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7.7 MAG

7.7 MAG

1-(7Z-tetradecenoyl)-rac-glycerol

This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C17H32O4
Percent Composition
C 67.96%, H 10.74%, O 21.30%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
749266-35-1
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
300.434
Exact Mass
300.230
Johner, N., S. Mondal, G. Morra, M. Caffrey, H. Weinstein, and G. Khelashvili. (2014). Protein and Lipid Interactions Driving Molecular Mechanisms of in meso Crystallization. J Am Chem Soc [PubMed] Caffrey, M. and C. Porter. (2010). Crystallizing membrane proteins for structure determination using lipidic mesophases. J Vis Exp 2010 Nov 21;(45). pii: 1712. doi: 10.3791/1712. [PubMed] Caffrey, M. and V. Cherezov. (2009). Crystallizing membrane proteins using lipidic mesophases. Nat Protoc 4:706-31. [PubMed] Hofer, N., D. Aragao, and M. Caffrey. (2010). Crystallizing transmembrane peptides in lipidic mesophases. Biophys J 99:L23-5. [PubMed] Misquitta, L.V., Y. Misquitta, V. Cherezov, O. Slattery, J.M. Mohan, D. Hart, M. Zhalnina, W.A. Cramer, and M. Caffrey. (2004). Membrane protein crystallization in lipidic mesophases with tailored bilayers. Structure 12:2113-24. [PubMed]