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Facade®-EM | 850522

3α-hydroxy-7α,12α-di-((O-ß-D-maltosyl)-2-hydroxyethoxy)-cholane
Exclusively from Avanti

850522P

Powder

500 mg
$1030.00
1 g
$1810.00
25 mg
$145.00
200 mg
$475.00

All Prices in US Dollars
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Exclusively from Avanti
Façade-EM is a two-dimensional amphiphile with hydrophobic and hydrophilic faces that has superior ability to stabilize integral membrane proteins. This new class of detergents represents a departure from traditional one-dimensional polar-head/nonpolar-tail molecules.
Molecular Formula
C52H90O25
Percent Composition
C 56.00%, H 8.13%, O 35.86%
Purity
>99%
Stability
1 Years
Storage
-20°C
CAS Number
1429405-95-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
1115.256
Exact Mass
1114.577
CMC
~0.18 mM (0.02 wt%)
Synonyms
FA-3
3α-hydroxy-7α,12α-di-((O-ß-D-maltopyranosyl)ethyloxy)-cholane
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Lee, S.C., B.C. Bennett, W.X. Hong, Y. Fu, K.A. Baker, J. Marcoux, C.V. Robinson, A.B. Ward, J.R. Halpert, R.C. Stevens, C.D. Stout, M.J. Yeager, and Q. Zhang. (2013). Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proc Natl Acad Sci U S A 110:E1203-11. [PubMed]

Zhang, Q., X. Ma, A. Ward, W.X. Hong, V.P. Jaakola, R.C. Stevens, M.G. Finn, and G. Chang. (2007) Designing facial amphiphiles for the stabilization of integral membrane proteins. Angew Chem Int Ed Engl 46:7023-5. [PubMed]