850501 | CHAPSO

3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate

CHAPSO

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1g 850501P-1g 850501P-1g 1 x 1g $125.15

Info

CHAPSO

3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate

Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state. Capable of solubilizing opiate receptor to a state exhibiting reversible binding of opiates. Has higher solubility than CHAPS because of its more polar head group.
Micellar average MW: 7000
Aggregation number: 11
Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C32H58N2O8S
Percent Composition
C 60.92%, H 9.27%, N 4.44%, O 20.29%, S 5.08%
Purity
>98%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
82473-24-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
630.877
Exact Mass
630.391
CMC
8 mM (20-25°C)
References

Simonds WF, Koski G, Streaty RA, Hjelmeland LM, Klee WA. Solubilization of active opiate receptors. Proc Natl Acad Sci U S A. 1980 Aug;77(8):4623-7. doi: 10.1073/pnas.77.8.4623. PMID: 6254034; PMCID: PMC349897.

PubMed ID: 6254034
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