850459 | 16:0-20:4 PC
1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine

16:0-20:4 PC
1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
CAS Registry Number is a Registered Trademark of the American Chemical Society
PAPC
PC(16:0/20:4(5Z,8Z,11Z,14Z))
- ChemDraw File
- 3D Structure
- Structure
- Safety Data Sheet
- Certificate of Analysis (Lot No. 850459C-25MG-D-163 and 5681CJD163)
- Certificate of Analysis (Lot No. 850459C-25MG-F-163 and 5681CJF163)
- Certificate of Analysis (Lot No. 850459C-200MG-H-163 and 5681CNH163)
- Certificate of Analysis (Lot No. 850459C-25MG-H-163 and 5681CJH163)
- Certificate of Analysis (Lot No. 850459C-200MG-K-163 and 5681CNK163)
- Certificate of Analysis (Lot No. 850459C-25MG-K-163 and 5681CJK163)
- Certificate of Analysis (Lot No. 850459C-25MG-M-163 and 5681CJM163)
- Certificate of Analysis (Lot No. 850459C-200MG-L-163 and 5681CNL163)
- Certificate of Analysis (Lot No. 850459C-25MG-L-163 and 5681CJL163)
- Certificate of Analysis (Lot No. 850459C-200MG-M-163 and 5681CNM163)
- Certificate of Analysis (Lot No. 850459C-25MG-N-163 and 5681CJN163)
- Certificate of Analysis (Lot No. 850459C-200MG-O-163 and 5681CNO163)
- Certificate of Analysis (Lot No. 850459C-25MG-O-163 and 5681CJO163)
- Certificate of Analysis (Lot No. 850459C-200MG-P-163 and 5681CNP163)
- Certificate of Analysis (Lot No. 850459C-25MG-P-163 and 5681CJP163)
- Certificate of Analysis (Lot No. 850459C-200MG-Q-163 and 5681CNQ163)
- Certificate of Analysis (Lot No. 850459C-25MG-Q-163 and 5681CJQ163)
- Certificate of Analysis (Lot No. 850459C-25MG-R-163 and 5681CJR163)
- Certificate of Analysis (Lot No. 850459C-25MG-S-163 and 5681CJS163)
- Certificate of Analysis (Lot No. 850459C-200MG-S-163 and 5681CNS163)
- Certificate of Analysis (Lot No. 850459C-25MG-T-163 and 5681CJT163)
- Certificate of Analysis (Lot No. 850459C-25MG-U-163 and 5681CJU163)
- Certificate of Analysis (Lot No. 850459C-200MG-U-163 and 5681CNU163)
- Certificate of Analysis (Lot No. 850459C-25MG-V-163 and 5681CJV163)
- Certificate of Analysis (Lot No. 850459C-200MG-B-164 and 5681CNB164)
- Certificate of Analysis (Lot No. 850459C-200MG-C-164 and 5681CNC164)
- Certificate of Analysis (Lot No. 850459C-25MG-C-164 and 5681CJC164)
- Certificate of Analysis (Lot No. 850459C-25MG-D-164 and 5681CJD164)
Valdivia AO, Agarwal PK, Bhattacharya SK. Myelin Basic Protein Phospholipid Complexation Likely Competes with Deimination in Experimental Autoimmune Encephalomyelitis Mouse Model. ACS Omega. 2020 Jun 16;5(25):15454-15467. doi: 10.1021/acsomega.0c01590. PMID: 32637820; PMCID: PMC7331039.
PubMed ID: 32637820Muri J, Feng Q, Wolleb H, Shamshiev A, Ebner C, Tortola L, Broz P, Carreira EM, Kopf M. Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways. Cell Rep. 2020 Mar 31;30(13):4399-4417.e7. doi: 10.1016/j.celrep.2020.03.019. PMID: 32234476.
PubMed ID: 32234476Di Gioia M, Spreafico R, Springstead JR, Mendelson MM, Joehanes R, Levy D, Zanoni I.Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation. Nat Immunol. 2020 Jan;21(1):42-53. doi: 10.1038/s41590-019-0539-2. Epub 2019 Nov 25.
PubMed ID: 31768073Ni Z, Sousa BC, Colombo S, Afonso CB, Melo T, Pitt AR, Spickett CM, Domingues P, Domingues MR, Fedorova M, Criscuolo A. Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS. Free Radic Biol Med. 2019 Jun 15. pii: S0891-5849(19)30347-8. doi: 10.1016/j.freeradbiomed.2019.06.013. [Epub ahead of print]
PubMed ID: 31212065Imbs AB, Dang LPT, Nguyen KB. Comparative lipidomic analysis of phospholipids of hydrocorals and corals from tropical and cold-water regions. PLoS One. 2019 Apr 29;14(4):e0215759. doi: 10.1371/journal.pone.0215759. eCollection 2019.
PubMed ID: 31034482Daniel J. Stephenson, H. Patrick MacKnight, L. Alexis Hoeferlin, Margaret A. Park, Jeremy C. Allegood, Christopher L. Cardona, and Charles E. Chalfant. A rapid and adaptable lipidomics method for quantitative UPLC-mass spectrometric analysis of phosphatidylethanolamine and phosphatidylcholine in vitro, and in cells. Anal. Methods, 2019,11, 1765-1776. doi: 10.1039/C9AY00052F
Parra-Ortiz E, Browning KL, Damgaard LSE, Nordström R, Micciulla S, Bucciarelli S, Malmsten M. Effects of oxidation on the physicochemical properties of polyunsaturated lipid membranes. J Colloid Interface Sci. 2019 Mar 7;538:404-419. doi: 10.1016/j.jcis.2018.12.007. Epub 2018 Dec 3.
PubMed ID: 30530078Ke Y, Karki P, Kim J, Son S, Berdyshev E, Bochkov VN, Birukova AA, Birukov KG. Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. FASEB J. 2018 Dec 6:fj201800981R. doi: 10.1096/fj.201800981R. [Epub ahead of print].
PubMed ID: 30521374Turner, W.W., K. Hartvigsen, A. Boullier, E.N. Montano, J.L. Witztum, and M.S. VanNieuwenhze. (2012). Design and synthesis of a stable oxidized phospholipid mimic with specific binding recognition for macrophage scavenger receptors. J Med Chem 55:8178-82.
PubMed ID: 22934615Ausili A, Martinez Valera P, Torrecillas A, Gómez-Murcia V, deGodos AM, Corbalan-Garcia S, Teruel JA, Gomez-Fernandez JC. The anticancer agent edelfosine exhibits a high affinity for cholesterol and disorganizes liquid ordered membrane structures. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01539. [Epub ahead of print]
PubMed ID: 29924618