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Products

16:0-18:1 PC | 850457

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine

850457P

Powder

850457P-
25mg
$67.00
850457P-
200mg
$174.00
850457P-
500mg
$305.00
850457P-
1g
$450.00

850457C

Chloroform

850457C-
25mg
$67.00
850457C-
200mg
$174.00
850457C-
500mg
$305.00
850457C-
1g
$450.00

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POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.
Molecular Formula
C42H82NO8P
Percent Composition
C 66.37%, H 10.87%, N 1.84%, O 16.84%, P 4.08%
Purity
>99%
Stability
1 Year
Storage
-20°C
CAS Number
26853-31-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
760.076
Exact Mass
759.578
Transition Temp
-2°C
Synonyms
1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
POPC
PC(16:0/18:1(9Z))
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
James Kurniawan, João Ventrici, Gregory Kittleson and Tonya L. Kuhl Interaction Forces between Lipid Rafts. Langmuir. Publication Date (Web): December 21, 2016 DOI: 10.1021/acs.langmuir.6b03717

What Is the Preferred Conformation of Phosphatidylserine–Copper(II) Complexes? A Combined Theoretical and Experimental Investigation Kari Kusler, Samuel O. Odoh, Alexey Silakov, Matthew F. Poyton, Saranya Pullanchery, Paul S. Cremer and Laura Gagliardi J. Phys. Chem. B, Article ASAP DOI: 10.1021/acs.jpcb.6b10675

Nuria Roldan,Thomas K.M. Nyholm,J. Peter Slotte,Jesús Pérez-Gil,Begoña García-Álvarez. (2016). Effect of Lung Surfactant Protein SP-C and SP-C-Promoted Membrane Fragmentation on Cholesterol Dynamics. Biophysical Journal 111(8):1703-1713. [Click Here]

Victor, K.G., J.P. Korb, and R.G. Bryant. (2013). Translational Dynamics of Water at the Phospholipid Interface. J Phys Chem B Sep 23, 2013 [PubMed]

Acyl Chain Length and Saturation Modulate Interleaflet Coupling in Asymmetric Bilayers: Effects on Dynamics and Structural Order. Salvatore Chiantia and Erwin London, Biophysical Journal, Volume 103, Issue 11, 2311-2319, 5 December 2012. [Abstract]

Jerabek, H., G. Pabst, M. Rappolt, and T. Stockner. (2010). Membrane-mediated effect on ion channels induced by the anesthetic drug ketamine. J Am Chem Soc 132:7990-7. [PubMed]

Mark J. Richards and Susan Daniel, Two-Phase Contiguous Supported Lipid Bilayer Model for Membrane Rafts via Polymer Blotting and Stenciling, Langmuir, Article ASAP DOI: 10.1021/acs.langmuir.6b04385

Shin, Y.K. and W.L. Hubbell. (1992). Determination of electrostatic potentials at biological interfaces using electron-electron double resonance. Biophys J 61:1443-53. [PubMed]

James Kruczek, See-Wing Chiu, Eric Jakobsson and Sagar A. Pandit, Effects of Lithium and Other Monovalent Ions on Palmitoyl Oleoyl Phosphatidylcholine Bilayer, Langmuir, Article ASAP DOI: 10.1021/acs.langmuir.6b04166

Nanoroughness Strongly Impacts Lipid Mobility in Supported Membranes Florence Blachon†, Frédéric Harb‡, Bogdan Munteanu§, Agnès Piednoir†, Rémy Fulcrand†, Thierry Charitat∥, Giovanna Fragneto⊥, Olivier Pierre-Louis†, Bernard Tinland#, and Jean-Paul Rieu*†  Langmuir, Article ASAP [PubMed]

Charles G. Cranfield, Sónia Troeira Henriques, Boris Martinac, Paul Duckworth, David J. Craik and Bruce Cornell. Kalata B1 and Kalata B2 Have a Surfactant-Like Activity in Phosphatidylethanolomine-Containing Lipid Membranes. Langmuir, Article ASAP [PubMed]

Ling Han, Luis C. Morales, Michele R. Richards, Elena N. Kitova, Simonetta Sipione and John S. Klassen. Investigating the Influence of Membrane Composition on Protein–Glycolipid Binding Using Nanodiscs and Proxy Ligand Electrospray Ionization Mass Spectrometry. Anal. Chem., Article ASAP [PubMed]

Yixing Chen, Halil I. Okur, Cornelis Lütgebaucks, and Sylvie Roke. Zwitterionic and charged lipids form remarkably different structures on nanoscale oil droplets in aqueous solution. Langmuir, Just Accepted Manuscript. [PubMed]

Saba Ghazvini, Ryan Alonso, Nabil Alhakamy, and Prajnaparamita Dhar. pH induced changes in the surface viscosity of unsaturated phospholipids monitored using active interfacial microrheology. Langmuir, Just Accepted Manuscript [PubMed]

Maria J. Sarmento, Ana Coutinho, Aleksander Fedorov, Manuel Prieto, and Fabio Fernandes. Membrane Order Is a Key Regulator of Divalent Cation-Induced Clustering of PI(3,5)P2 and PI(4,5)P2. Langmuir. Article ASAP. [PubMed]

Masato Abe, Yoshiki Sawada, Shinpei Uno, Shuhei Chigasaki, Masahide Oku, Yasuyoshi Sakai, and Hideto Miyoshi. Role of Acyl Chain Composition of Phosphatidylcholine in Tafazzin-Mediated Remodeling of Cardiolipin in Liposomes. Biochemistry, Article ASAP [PubMed]