Products

16:0-18:1 PC | 850457

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine

850457P

Powder

25 mg
$64.00
200 mg
$165.00
500 mg
$290.00
1 g
$425.00

850457C

Chloroform

25 mg
$49.00
200 mg
$150.00
500 mg
$275.00
1 g
$410.00

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POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.
Molecular Formula
C42H82NO8P
Percent Composition
C 66.37%, H 10.87%, N 1.84%, O 16.84%, P 4.08%
Purity
>99%
Stability
6 Months
Storage
-20°C
CAS Number
26853-31-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
760.076
Exact Mass
759.578
Transition Temp
-2°C
Synonyms
1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
POPC
PC(16:0/18:1(9Z))
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Nuria Roldan,Thomas K.M. Nyholm,J. Peter Slotte,Jesús Pérez-Gil,Begoña García-Álvarez. (2016). Effect of Lung Surfactant Protein SP-C and SP-C-Promoted Membrane Fragmentation on Cholesterol Dynamics. Biophysical Journal 111(8):1703-1713. [Click Here]

Victor, K.G., J.P. Korb, and R.G. Bryant. (2013). Translational Dynamics of Water at the Phospholipid Interface. J Phys Chem B Sep 23, 2013 [PubMed]

Acyl Chain Length and Saturation Modulate Interleaflet Coupling in Asymmetric Bilayers: Effects on Dynamics and Structural Order. Salvatore Chiantia and Erwin London, Biophysical Journal, Volume 103, Issue 11, 2311-2319, 5 December 2012. [Abstract]

Jerabek, H., G. Pabst, M. Rappolt, and T. Stockner. (2010). Membrane-mediated effect on ion channels induced by the anesthetic drug ketamine. J Am Chem Soc 132:7990-7. [PubMed]

Shin, Y.K. and W.L. Hubbell. (1992). Determination of electrostatic potentials at biological interfaces using electron-electron double resonance. Biophys J 61:1443-53. [PubMed]