850457 | 16:0-18:1 PC (POPC)
1-palmitoyl-2-oleoyl-glycero-3-phosphocholine

16:0-18:1 PC (POPC)
1-palmitoyl-2-oleoyl-glycero-3-phosphocholine
POPC is typically considered one of the model lipids for biophysical experiments. The fatty acid composition, i.e., saturated chain in the sn-1 position and unsaturated chain in the sn-2 position, mimics mammalian phospholipid composition. Since the major constituent in Egg PC is 1-palmitoyl-2-oleoyl PC, POPC is an excellent synthetic substitute for EPC.
CAS Registry Number is a Registered Trademark of the American Chemical Society
POPC
PC(16:0/18:1(9Z))
- ChemDraw File
- 3D Structure
- Structure
- Safety Data Sheet
- Certificate of Analysis (Lot No. 850457C-25MG-A-207 and 5679CJA207)
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- Certificate of Analysis (Lot No. 850457P-200MG-A-211 and 5679PNA211)
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- Certificate of Analysis (Lot No. 850457P-200MG-E-216 and 5679PNE216)
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- Certificate of Analysis (Lot No. 850457C-1G-D-216 and 5679CQD216)
- Certificate of Analysis (Lot No. 850457P-500MG-E-216 and 5679PPE216)
- Certificate of Analysis (Lot No. 850457P-25MG-D-216 and 5679PJD216)
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PubMed ID: 32325956Piecyk K, Pietrow P, Arnold T, Worch R, Korneeva NL, Jankowska-Anyszka M. Effect of HIV-1 TAT Peptide Fusion on 5' mRNA Cap Analogs Cell Membrane Permeability and Translation Inhibition. Bioconjug Chem. 2020 Apr 15;31(4):1156-1166. doi: 10.1021/acs.bioconjchem.0c00080. Epub 2020 Mar 31. PMID: 32227927.
PubMed ID: 32227927Lee H, Jiang D, Pardridge WM. Lyoprotectant Optimization for the Freeze-Drying of Receptor-Targeted Trojan Horse Liposomes for Plasmid DNA Delivery. Mol Pharm. 2020 Apr 29. doi: 10.1021/acs.molpharmaceut.0c00310. Epub ahead of print. PMID: 32315188.
PubMed ID: 32315188Jephthah S, Månsson LK, Belić D, Morth JP, Skepö M. Physicochemical Characterisation of KEIF-The Intrinsically Disordered N-Terminal Region of Magnesium Transporter A. Biomolecules. 2020 Apr 17;10(4):623. doi: 10.3390/biom10040623. PMID: 32316569; PMCID: PMC7226168.
PubMed ID: 32316569Koseki K, Suzuki H. Deformation Dynamics of Giant Unilamellar Vesicles in the Large Surface-to-Volume Ratio Regime: The Emergence of Neuron-like Morphology. Langmuir. 2020 May 18. doi: 10.1021/acs.langmuir.0c00872. Epub ahead of print. PMID: 32364747.
PubMed ID: 32364747Pols T, Singh S, Deelman-Driessen C, Gaastra BF, Poolman B. Enzymology of the pathway for ATP production by arginine breakdown. FEBS J. 2020 Apr 18. doi: 10.1111/febs.15337. Epub ahead of print. PMID: 32306469.
PubMed ID: 32306469Sun J, Singaram I, Soflaee MH, Cho W. A Direct Fluorometric Activity Assay for Lipid Kinases and Phosphatases. J Lipid Res. 2020 Apr 27:jlr.D120000794. doi: 10.1194/jlr.D120000794. Epub ahead of print. PMID: 32341006.
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PubMed ID: 32277854Gozem S, Johnson PJM, Halpin A, Luk HL, Morizumi T, Prokhorenko VI, Ernst OP, Olivucci M, Miller RJD. Excited-State Vibronic Dynamics of Bacteriorhodopsin from Two-Dimensional Electronic Photon Echo Spectroscopy and Multiconfigurational Quantum Chemistry. J Phys Chem Lett. 2020 May 4:3889-3896. doi: 10.1021/acs.jpclett.0c01063. Epub ahead of print. PMID: 32330041.
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PubMed ID: 32320255Santos TCB, Vaz A, Ventura AE, M Saied E, Arenz C, Fedorov A, Prieto M, Silva LC. Canonical and 1-Deoxy(methyl) Sphingoid Bases: Tackling the Effect of the Lipid Structure on Membrane Biophysical Properties. Langmuir. 2020 May 15. doi: 10.1021/acs.langmuir.0c01000. Epub ahead of print. PMID: 32369370.
PubMed ID: 32369370Domingues TM, Perez KR, Riske KA. Revealing the mode of action of halictine antimicrobial peptides: a comprehensive study with model membranes. Langmuir. 2020 Apr 27. doi: 10.1021/acs.langmuir.0c00282. Epub ahead of print. PMID: 32336099.
PubMed ID: 32336099Yandrapalli N, Seemann T, Robinson T. On-Chip Inverted Emulsion Method for Fast Giant Vesicle Production, Handling, and Analysis. Micromachines (Basel). 2020 Mar 10;11(3):285. doi: 10.3390/mi11030285. PMID: 32164221; PMCID: PMC7142477.
PubMed ID: 32164221Maravilla E, Le DP, Tran JJ, Chiu MH, Prenner EJ, Weers PMM. Apolipophorin III interaction with phosphatidylglycerol and lipopolysaccharide: A potential mechanism for antimicrobial activity. Chem Phys Lipids. 2020 Mar 21;229:104909. doi: 10.1016/j.chemphyslip.2020.104909. Epub ahead of print. PMID: 32209325.
PubMed ID: 32209325Zhang W, Metzger JM, Hackel BJ, Bates FS, Lodge TP. Influence of the Headgroup on the Interaction of Poly(ethylene oxide)-Poly(propylene oxide) Block Copolymers with Lipid Bilayers. J Phys Chem B. 2020 Mar 26;124(12):2417-2424. doi: 10.1021/acs.jpcb.0c00553. Epub 2020 Mar 16. PMID: 32175743.
PubMed ID: 32175743Passos Gibson V, Fauquignon M, Ibarboure E, Leblond Chain J, Le Meins JF. Switchable Lipid Provides pH-Sensitive Properties to Lipid and Hybrid Polymer/Lipid Membranes. Polymers (Basel). 2020 Mar 11;12(3):E637. doi: 10.3390/polym12030637. PMID: 32168824.
PubMed ID: 32168824Pham QD, Carlström G, Lafon O, Sparr E, Topgaard D. Quantification of the amount of mobile components in intact stratum corneum with natural-abundance 13C solid-state NMR. Phys Chem Chem Phys. 2020 Mar 25;22(12):6572-6583. doi: 10.1039/d0cp00079e. PMID: 32159206.
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PubMed ID: 32246901Josey BP, Heinrich F, Silin V, Lösche M. Association of Model Neurotransmitters with Lipid Bilayer Membranes. Biophys J. 2020 Mar 10;118(5):1044-1057. doi: 10.1016/j.bpj.2020.01.016. Epub 2020 Jan 28. PMID: 32032504; PMCID: PMC7063487.
PubMed ID: 32032504Malabed R, Hanashima S, Murata M, Sakurai K. Interactions of OSW-1 with Lipid Bilayers in Comparison with Digitonin and Soyasaponin. Langmuir. 2020 Apr 7;36(13):3600-3610. doi: 10.1021/acs.langmuir.9b03957. Epub 2020 Mar 30. PMID: 32160747.
PubMed ID: 32160747Bryce DA, Kitt JP, Myres GJ, Harris JM. Confocal Raman Microscopy Investigation of Phospholipid Monolayers Deposited on Nitrile-Modified Surfaces in Porous Silica Particles. Langmuir. 2020 Apr 21;36(15):4071-4079. doi: 10.1021/acs.langmuir.0c00456. Epub 2020 Apr 7. PMID: 32212663.
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PubMed ID: 32216370Olżyńska A, Wizert A, Štefl M, Iskander DR, Cwiklik L. Mixed polar-nonpolar lipid films as minimalistic models of Tear Film Lipid Layer: A Langmuir trough and fluorescence microscopy study. Biochim Biophys Acta Biomembr. 2020 Mar 31;1862(9):183300. doi: 10.1016/j.bbamem.2020.183300. Epub ahead of print. PMID: 32243884.
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PubMed ID: 32179778Dazzoni R, Grélard A, Morvan E, Bouter A, Applebee CJ, Loquet A, Larijani B, Dufourc EJ. The unprecedented membrane deformation of the human nuclear envelope, in a magnetic field, indicates formation of nuclear membrane invaginations. Sci Rep. 2020 Mar 20;10(1):5147. doi: 10.1038/s41598-020-61746-0. PMID: 32198481; PMCID: PMC7083927.
PubMed ID: 32198481Tao M, Isas JM, Langen R. Annexin B12 Trimer Formation is Governed by a Network of Protein-Protein and Protein-Lipid Interactions. Sci Rep. 2020 Mar 24;10(1):5301. doi: 10.1038/s41598-020-62343-x. PMID: 32210350; PMCID: PMC7093510.
PubMed ID: 32210350Agwa AJ, Tran P, Mueller A, Tran HNT, Deuis JR, Israel MR, McMahon KL, Craik DJ, Vetter I, Schroeder CI. Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7. J Biol Chem. 2020 Apr 10;295(15):5067-5080. doi: 10.1074/jbc.RA119.012281. Epub 2020 Mar 5. PMID: 32139508; PMCID: PMC7152767.
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PubMed ID: 32334685Vasquez-Montes V, Kyrychenko A, Vargas-Uribe M, Rodnin MV, Ladokhin AS. Conformational Switching in Bcl-xL: Enabling Non-Canonic Inhibition of Apoptosis Involves Multiple Intermediates and Lipid Interactions. Cells. 2020 Feb 26;9(3):539. doi: 10.3390/cells9030539. PMID: 32111007; PMCID: PMC7140517.
PubMed ID: 32111007Cohen DT, Wales TE, McHenry MW, Engen JR, Walensky LD. Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX. Cell Rep. 2020 Mar 10;30(10):3229-3239.e6. doi: 10.1016/j.celrep.2020.02.057. PMID: 32160532.
PubMed ID: 32160532Yong X, Zhao L, Deng W, Sun H, Zhou X, Mao L, Hu W, Shen X, Sun Q, Billadeau DD, Xue Y, Jia D. Mechanism of cargo recognition by retromer-linked SNX-BAR proteins. PLoS Biol. 2020 Mar 9;18(3):e3000631. doi: 10.1371/journal.pbio.3000631. PMID: 32150533; PMCID: PMC7082075.
PubMed ID: 32150533Yin L, Masuyer G, Zhang S, Zhang J, Miyashita SI, Burgin D, Lovelock L, Coker SF, Fu TM, Stenmark P, Dong M. Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. PLoS Biol. 2020 Mar 17;18(3):e3000618. doi: 10.1371/journal.pbio.3000618. PMID: 32182233; PMCID: PMC7077807.
PubMed ID: 32182233Newberry RW, Leong JT, Chow ED, Kampmann M, DeGrado WF. Deep mutational scanning reveals the structural basis for α-synuclein activity. Nat Chem Biol. 2020 Mar 9. doi: 10.1038/s41589-020-0480-6. Epub ahead of print. PMID: 32152544.
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PubMed ID: 32160747Nigam P. Equilibrium penetration of pluronic F-68 in lipid monolayers. Chem Phys Lipids. 2020 May;228:104888. doi: 10.1016/j.chemphyslip.2020.104888. Epub 2020 Feb 4. PMID: 32032569.
PubMed ID: 32032569Gottipati K, Woodson M, Choi KH. Membrane binding and rearrangement by chikungunya virus capping enzyme nsP1. Virology. 2020 May;544:31-41. doi: 10.1016/j.virol.2020.02.006. Epub 2020 Feb 24. PMID: 32174512; PMCID: PMC7103501.
PubMed ID: 32174512Chakraborty A, Hertel A, Ditmars H, Dhar P. Impact of Engineered Carbon Nanodiamonds on the Collapse Mechanism of Model Lung Surfactant Monolayers at the Air-Water Interface. Molecules. 2020 Feb 7;25(3):714. doi: 10.3390/molecules25030714. PMID: 32046011; PMCID: PMC7037128.
PubMed ID: 32046011Wang CR, Bubner ER, Jovcevski B, Mittal P, Pukala TL. Interrogating the higher order structures of snake venom proteins using an integrated mass spectrometric approach. J Proteomics. 2020 Mar 30;216:103680. doi: 10.1016/j.jprot.2020.103680. Epub 2020 Feb 3. PMID: 32028038.
PubMed ID: 32028038Latza VM, Demé B, Schneck E. Membrane Adhesion via Glycolipids Occurs for Abundant Saccharide Chemistries. Biophys J. 2020 Feb 12:S0006-3495(20)30122-3. doi: 10.1016/j.bpj.2020.02.003. Epub ahead of print. PMID: 32097623.
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PubMed ID: 32044518Al-Adwani S, Wallin C, Balhuizen MD, Veldhuizen EJA, Coorens M, Landreh M, Végvári Á, Smith ME, Qvarfordt I, Lindén A, Gräslund A, Agerberth B, Bergman P. Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties. Sci Rep. 2020 Feb 11;10(1):2376. doi: 10.1038/s41598-020-59071-7. PMID: 32047184; PMCID: PMC7012854.
PubMed ID: 32047184Banerjee S, Hashemi M, Zagorski K, Lyubchenko YL. Interaction of Aβ42 with Membranes Triggers the Self-Assembly into Oligomers. Int J Mol Sci. 2020 Feb 8;21(3):1129. doi: 10.3390/ijms21031129. PMID: 32046252; PMCID: PMC7036922.
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PubMed ID: 32212610Yeh V, Goode A, Eastham G, Rambo R, Inoue K, Doutch JJ, Bonev BB. Membrane stability in the presence of methacrylate esters. Langmuir. 2020 Mar 23. doi: 10.1021/acs.langmuir.9b03759. Epub ahead of print. PMID: 32202793.
PubMed ID: 32202793Frame NM, Kumanan M, Wales TE, Bandara A, Fändrich M, Straub JE, Engen JR, Gursky O. Structural Basis for Lipid Binding and Function by an Evolutionarily Conserved Protein, Serum Amyloid A. J Mol Biol. 2020 Feb 6:S0022-2836(20)30093-0. doi: 10.1016/j.jmb.2020.01.029. Epub ahead of print. PMID: 32035904.
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PubMed ID: 32040508Lee SH, Lee M, Yang H, Cho Y, Hong S, Park TH. Bioelectronic sensor mimicking the human neuroendocrine system for the detection of hypothalamic-pituitary-adrenal axis hormones in human blood. Biosens Bioelectron. 2020 Apr 15;154:112071. doi: 10.1016/j.bios.2020.112071. Epub 2020 Feb 3. PMID: 32056965.
PubMed ID: 32056965Fujioka Y, Alam JM, Noshiro D, Mouri K, Ando T, Okada Y, May AI, Knorr RL, Suzuki K, Ohsumi Y, Noda NN. Phase separation organizes the site of autophagosome formation. Nature. 2020 Feb;578(7794):301-305. doi: 10.1038/s41586-020-1977-6. Epub 2020 Feb 5. PMID: 32025038.
PubMed ID: 32025038Kitamata M, Hotta M, Hamada-Nakahara S, Suetsugu S. The membrane binding and deformation property of vaccinia virus K1 ankyrin repeat domain protein. Genes Cells. 2020 Jan 24:10.1111/gtc.12749. doi: 10.1111/gtc.12749. Epub ahead of print. PMID: 31976592.
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