850371 | 22:0 PC

1,2-dibehenoyl-sn-glycero-3-phosphocholine


Chloroform

Size SKU Packaging Price
25mg 850371C-25mg 850371C-25mg 1 x 25mg 10mg/mL 2.5mL $94.00
500mg 850371C-500mg 850371C-500mg 1 x 500mg 25mg/mL 20mL $270.00

Powder

Size SKU Packaging Price
25mg 850371P-25mg 850371P-25mg 1 x 25mg $94.00
500mg 850371P-500mg 850371P-500mg 1 x 500mg $270.00
1g 850371P-1g 850371P-1g 1 x 1g $420.00
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22:0 PC

22:0 PC

1,2-dibehenoyl-sn-glycero-3-phosphocholine

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C52H104NO8P
Percent Composition
C 69.21%, H 11.62%, N 1.55%, O 14.18%, P 3.43%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
37070-48-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
902.358
Exact Mass
901.750
Synonyms
1,2-didocosanoyl-sn-glycero-3-phosphocholine
PC(22:0/22:0)

Nittayacharn P, Abenojar E, De Leon A, Wegierak D, Exner AA. Increasing Doxorubicin Loading in Lipid-Shelled Perfluoropropane Nanobubbles via a Simple Deprotonation Strategy. Front Pharmacol. 2020 May 12;11:644. doi: 10.3389/fphar.2020.00644. PMID: 32477125; PMCID: PMC7235281.

PubMed ID: 32477125

Ramirez DG, Abenojar E, Hernandez C, Lorberbaum DS, Papazian LA, Passman S, Pham V, Exner AA, Benninger RKP. Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes. Nat Commun. 2020 May 7;11(1):2238. doi: 10.1038/s41467-020-15957-8. PMID: 32382089; PMCID: PMC7206014.

PubMed ID: 32382089

Shakya G, Hoff SE, Wang S, Heinz H, Ding X, Borden MA. Vaporizable endoskeletal droplets via tunable interfacial melting transitions. Sci Adv. 2020 Apr 3;6(14):eaaz7188. doi: 10.1126/sciadv.aaz7188. PMID: 32284985; PMCID: PMC7124936.

PubMed ID: 32284985

Reusser TD, Song KH, Ramirez D, Benninger RK, Papadopoulou V, Borden MA. Phospholipid Oxygen Microbubbles for Image-Guided Therapy. Nanotheranostics. 2020 Feb 28;4(2):83-90. doi: 10.7150/ntno.43808. PMID: 32190535; PMCID: PMC7064740.

PubMed ID: 32190535

Abenojar EC, Bederman I, Leon AC, Zhu J, Hadley J, Kolios MC, Exner AA. Theoretical and Experimental Gas Volume Quantification of Micro- and Nanobubble Ultrasound Contrast Agents. Pharmaceutics. 2020 Mar 1;12(3):208. doi: 10.3390/pharmaceutics12030208. PMID: 32121484; PMCID: PMC7150797.

PubMed ID: 32121484

Cheng B, Bing C, Chopra R. The effect of transcranial focused ultrasound target location on the acoustic feedback control performance during blood-brain barrier opening with nanobubbles. Sci Rep. 2019 Dec 27;9(1):20020. doi: 10.1038/s41598-019-55629-2. PMID: 31882579; PMCID: PMC6934715.

PubMed ID: 31882579

Thompson E, Smart S, Kinchesh P, Bulte D, Stride E. Magnetic resonance imaging of oxygen microbubbles. Healthc Technol Lett. 2019 Aug 21;6(5):138-142. doi: 10.1049/htl.2018.5058. PMID: 31832209; PMCID: PMC6849496.

PubMed ID: 31832209

Beguin E, Gray MD, Logan KA, Nesbitt H, Sheng Y, Kamila S, Barnsley LC, Bau L, McHale AP, Callan JF, Stride E. Magnetic microbubble mediated chemo-sonodynamic therapy using a combined magnetic-acoustic device. J Control Release. 2019 Nov 13;317:23-33. doi: 10.1016/j.jconrel.2019.11.013. [Epub ahead of print]

PubMed ID: 31733295

He R, Huang Q, Yan X, Liu Y, Yang J, Chen X. A Case of Paradoxical Embolism Causing Anterior Spinal Cord Syndrome and Acute Myocardial Infarction Following the Intradiscal Oxygen-Ozone Therapy. Front Neurol. 2019 Feb 22;10:137. doi: 10.3389/fneur.2019.00137. eCollection 2019.

PubMed ID: 30853936

Cheng B, Bing C, Xi Y, Shah B, Exner AA, Chopra R. Influence of Nanobubble Concentration on Blood-Brain Barrier Opening Using Focused Ultrasound Under Real-Time Acoustic Feedback Control. Ultrasound Med Biol. 2019 Aug;45(8):2174-2187. doi: 10.1016/j.ultrasmedbio.2019.03.016. Epub 2019 May 7.

PubMed ID: 31072657

Blum NT, Yildirim A, Gyorkos C, Shi D, Cai A, Chattaraj R, Goodwin AP. Temperature-Responsive Hydrophobic Silica Nanoparticle Ultrasound Contrast Agents Directed by Phospholipid Phase Behavior. ACS Appl Mater Interfaces. 2019 May 1;11(17):15233-15240. doi: 10.1021/acsami.8b22659. Epub 2019 Apr 23.

PubMed ID: 31012297

Beguin E, Shrivastava S, Dezhkunov NV, McHale AP, Callan JF, Stride E. Direct Evidence of Multibubble Sonoluminescence Using Therapeutic Ultrasound and Microbubbles. ACS Appl Mater Interfaces. 2019 Jun 5;11(22):19913-19919. doi: 10.1021/acsami.9b07084. Epub 2019 May 22.

PubMed ID: 31074968

Logan K, Foglietta F, Nesbitt H, Sheng Y, McKaig T, Kamila S, Gao J, Nomikou N, Callan B, McHale AP, Callan JF. Targeted chemo-sonodynamic therapy treatment of breast tumours using ultrasound responsive microbubbles loaded with paclitaxel, doxorubicin and Rose Bengal. Eur J Pharm Biopharm. 2019 Jun;139:224-231. doi: 10.1016/j.ejpb.2019.04.003. Epub 2019 Apr 5.

PubMed ID: 30959180

Abenojar EC, Nittayacharn P, de Leon AC, Perera R, Wang Y, Bederman I, Exner AA. Effect of Bubble Concentration on the in Vitro and in Vivo Performance of Highly Stable Lipid Shell-Stabilized Micro- and Nanoscale Ultrasound Contrast Agents. Langmuir. 2019 Apr 9. doi: 10.1021/acs.langmuir.9b00462. [Epub ahead of print]

PubMed ID: 30913884

Beguin E, Bau L, Shrivastava S, Stride E. Comparing Strategies for Magnetic Functionalization of Microbubbles. ACS Appl Mater Interfaces. 2019 Jan 16;11(2):1829-1840. doi: 10.1021/acsami.8b18418. Epub 2019 Jan 7.

PubMed ID: 30574777