850365 | 18:0 PC (DSPC)

1,2-distearoyl-sn-glycero-3-phosphocholine

Chloroform

Size SKU Packaging Price
25mg 850365C-25mg 850365C-25mg 1 x 25mg 10mg/mL 2.5mL $48.75
200mg 850365C-200mg 850365C-200mg 2 x 100mg 25mg/mL 4mL $78.00
500mg 850365C-500mg 850365C-500mg 1 x 500mg 25mg/mL 20mL $130.00
1g 850365C-1g 850365C-1g 2 x 500mg 25mg/mL 20mL $180.00

Powder

Size SKU Packaging Price
25mg 850365P-25mg 850365P-25mg 1 x 25mg $48.75
200mg 850365P-200mg 850365P-200mg 1 x 200mg $78.00
500mg 850365P-500mg 850365P-500mg 1 x 500mg $130.00
1g 850365P-1g 850365P-1g 1 x 1g $180.00
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18:0 PC (DSPC)

18:0 PC (DSPC)

1,2-distearoyl-sn-glycero-3-phosphocholine

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C44H88NO8P
Percent Composition
C 66.88%, H 11.23%, N 1.77%, O 16.20%, P 3.92%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
816-94-4
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
790.145
Exact Mass
789.625
Synonyms
1,2-dioctadecanoyl-sn-glycero-3-phosphocholine
DSPC(18:0/18:0)

Cimorelli M, Flynn MA, Angel B, Fafarman A, Kohut A, Wrenn S. An Ultrasound Enhancing Agent with Nonlinear Acoustic Activity that Depends on the Presence of an Electric Field. Ultrasound Med Biol. 2020 Jun 29:S0301-5629(20)30242-8. doi: 10.1016/j.ultrasmedbio.2020.04.038. Epub ahead of print. PMID: 32616427.

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Mucker EM, Karmali PP, Vega J, Kwilas SA, Wu H, Joselyn M, Ballantyne J, Sampey D, Mukthavaram R, Sullivan E, Chivukula P, Hooper JW. Lipid Nanoparticle Formulation Increases Efficiency of DNA-Vectored Vaccines/Immunoprophylaxis in Animals Including Transchromosomic Bovines. Sci Rep. 2020 May 29;10(1):8764. doi: 10.1038/s41598-020-65059-0. PMID: 32472093; PMCID: PMC7260227.

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Cevenini A, Celia C, Orrù S, Sarnataro D, Raia M, Mollo V, Locatelli M, Imperlini E, Peluso N, Peltrini R, De Rosa E, Parodi A, Del Vecchio L, Di Marzio L, Fresta M, Netti PA, Shen H, Liu X, Tasciotti E, Salvatore F. Liposome-Embedding Silicon Microparticle for Oxaliplatin Delivery in Tumor Chemotherapy. Pharmaceutics. 2020 Jun 17;12(6):E559. doi: 10.3390/pharmaceutics12060559. PMID: 32560359.

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Cerroni B, Riva FR, Oddo L, Domenici F, Tortorella E, Toumia Y, Brasili F, Paradossi G. In vitro analysis of the trajectories of adhesive microbubbles approaching endothelial cells. J Colloid Interface Sci. 2020 Jun 5;578:758-767. doi: 10.1016/j.jcis.2020.06.009. Epub ahead of print. PMID: 32574909.

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Lou G, Anderluzzi G, Tandrup Schmidt S, Woods S, Gallorini S, Brazzoli M, Giusti F, Ferlenghi I, Johnson R, Roberts CW, O'Hagan DT, Baudner BC, Perrie Y. Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection. J Control Release. 2020 Jun 30:S0168-3659(20)30362-X. doi: 10.1016/j.jconrel.2020.06.027. Epub ahead of print. PMID: 32619745.

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Takechi-Haraya Y, Goda Y, Izutsu K, Sakai-Kato K. Instrument-Dependent Factors Affecting the Precision in the Atomic Force Microscopy Stiffness Measurement of Nanoscale Liposomes. Chem Pharm Bull (Tokyo). 2020;68(5):473-478. doi: 10.1248/cpb.c20-00067. PMID: 32378545.

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Abdalkader R, Unga J, Maruyama K, Yamashita F, Hashida M. The application of the in-situ hyperthermia emission from acoustic nanodroplets for theranostic dual-imaging and antitumor modalities. Biol Pharm Bull. 2020 May 2. doi: 10.1248/bpb.b20-00171. Epub ahead of print. PMID: 32378553.

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Supponen O, Upadhyay A, Lum J, Guidi F, Murray T, Vos HJ, Tortoli P, Borden M. The effect of size range on ultrasound-induced translations in microbubble populations. J Acoust Soc Am. 2020 May;147(5):3236. doi: 10.1121/10.0001172. PMID: 32486824; PMCID: PMC7205472.

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Goel L, Wu H, Kim H, Zhang B, Kim J, Dayton PA, Xu Z, Jiang X. Examining the Influence of Low-Dose Tissue Plasminogen Activator on Microbubble-Mediated Forward-Viewing Intravascular Sonothrombolysis. Ultrasound Med Biol. 2020 Jul;46(7):1698-1706. doi: 10.1016/j.ultrasmedbio.2020.03.012. Epub 2020 May 7. PMID: 32389332; PMCID: PMC7293952.

 PubMed ID: 32389332

Zaytseva YV, Adichtchev SV, Surovtsev NV. Raman study of temperature-induced hydrocarbon chain disorder in saturated phosphatidylcholines. Chem Phys Lipids. 2020 May 23;230:104926. doi: 10.1016/j.chemphyslip.2020.104926. Epub ahead of print. PMID: 32454008.

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Collins GC, Jing B, Lindsey BD. High contrast power Doppler imaging in side-viewing intravascular ultrasound imaging via angular compounding. Ultrasonics. 2020 Jun 2;108:106200. doi: 10.1016/j.ultras.2020.106200. Epub ahead of print. PMID: 32521337.

 PubMed ID: 32521337

Galan-Acosta L, Sierra C, Leppert A, Pouliopoulos AN, Kwon N, Noel RL, Tambaro S, Presto J, Nilsson P, Konofagou EE, Johansson J. Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons. Mol Cell Neurosci. 2020 Jun;105:103498. doi: 10.1016/j.mcn.2020.103498. Epub 2020 May 8. PMID: 32389804.

 PubMed ID: 32389804

Huang J, Hiraki S, Feigenson GW. Calculation of Liquid-Disordered/Liquid-Ordered Line Tension from Pairwise Lipid Interactions. J Phys Chem B. 2020 Jun 18;124(24):4949-4959. doi: 10.1021/acs.jpcb.0c03329. Epub 2020 Jun 4. PMID: 32436388.

 PubMed ID: 32436388

Caviglia C, Garbarino F, Canali C, Melander F, Raiteri R, Ferrari G, Sampietro M, Heiskanen A, Andresen TL, Zór K, Emnéus J. Monitoring cell endocytosis of liposomes by real-time electrical impedance spectroscopy. Anal Bioanal Chem. 2020 May 25. doi: 10.1007/s00216-020-02592-x. Epub ahead of print. PMID: 32451643.

 PubMed ID: 32451643

Harmon JS, Celingant-Copie CA, Kabinejadian F, Bull JL. Lipid Shell Retention and Selective Binding Capability Following Repeated Transient Acoustic Microdroplet Vaporization. Langmuir. 2020 Jun 23;36(24):6626-6634. doi: 10.1021/acs.langmuir.0c00320. Epub 2020 Jun 11. PMID: 32420747.

 PubMed ID: 32420747

Perley CC, Brocato RL, Wu H, Bausch C, Karmali PP, Vega JB, Cohen MV, Somerville B, Kwilas SA, Principe LM, Shamblin J, Chivukula P, Sullivan E, Hooper JW. Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models. Front Microbiol. 2020 May 7;11:832. doi: 10.3389/fmicb.2020.00832. PMID: 32508764; PMCID: PMC7252588.

 PubMed ID: 32508764

Naciute M, Niemi V, Kemp RA, Hook S. Lipid-encapsulated oral therapeutic peptide vaccines reduce tumour growth in an orthotopic mouse model of colorectal cancer. Eur J Pharm Biopharm. 2020 Jul;152:183-192. doi: 10.1016/j.ejpb.2020.04.020. Epub 2020 May 4. PMID: 32380167.

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Molska A, Nyman AKG, Sofias AM, Kristiansen KA, Hak S, Widerøe M. In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations. Eur J Pharm Biopharm. 2020 Jul;152:248-256. doi: 10.1016/j.ejpb.2020.05.003. Epub 2020 May 18. PMID: 32439308.

 PubMed ID: 32439308

Reddy GB, Kerr DL, Spasojevic I, Tovmasyan A, Hsu DS, Brigman BE, Somarelli JA, Needham D, Eward WC. Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) shows efficacy against Osteosarcoma. Mol Cancer Ther. 2020 May 5:molcanther.0689.2019. doi: 10.1158/1535-7163.MCT-19-0689. Epub ahead of print. PMID: 32371588.

 PubMed ID: 32371588

Woitok MM, Zoubek ME, Doleschel D, Bartneck M, Mohamed MR, Kießling F, Lederle W, Trautwein C, Cubero FJ. Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver disease. Cell Death Dis. 2020 May 11;11(5):343. doi: 10.1038/s41419-020-2571-4. PMID: 32393755; PMCID: PMC7214425.

 PubMed ID: 32393755

Lim SWZ, Wong YS, Czarny B, Venkatraman S. Microfluidic-directed self-assembly of liposomes: Role of interdigitation. J Colloid Interface Sci. 2020 Jun 2;578:47-57. doi: 10.1016/j.jcis.2020.05.114. Epub ahead of print. PMID: 32505913.

 PubMed ID: 32505913

Kim B, Shin J, Kiziltepe T, Bilgicer B. Identification of a moderate affinity CD22 binding peptide and in vitro optimization of peptide-targeted nanoparticles for selective uptake by CD22+ B-cell malignancies. Nanoscale. 2020 Jun 4;12(21):11672-11683. doi: 10.1039/d0nr02133d. PMID: 32436925.

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Zhang J, Shen H, Xu J, Liu L, Tan J, Li M, Xu N, Luo S, Wang J, Yang F, Tang J, Li Q, Wang Y, Yu L, Yan Z. Liver-Targeted siRNA Lipid Nanoparticles Treat Hepatic Cirrhosis by Dual Antifibrotic and Anti-inflammatory Activities. ACS Nano. 2020 May 26;14(5):6305-6322. doi: 10.1021/acsnano.0c02633. Epub 2020 May 11. PMID: 32378877.

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Sofias AM, Toner YC, Meerwaldt AE, van Leent MMT, Soultanidis G, Elschot M, Gonai H, Grendstad K, Flobak Å, Neckmann U, Wolowczyk C, Fisher EL, Reiner T, Davies CL, Bjørkøy G, Teunissen AJP, Ochando J, Pérez-Medina C, Mulder WJM, Hak S. Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking. ACS Nano. 2020 May 20. doi: 10.1021/acsnano.9b08693. Epub ahead of print. PMID: 32413260.

 PubMed ID: 32413260

Zamani P, Navashenaq JG, Teymouri M, Karimi M, Mashreghi M, Jaafari MR. Combination therapy with liposomal doxorubicin and liposomal vaccine containing E75, an HER-2/neu-derived peptide, reduces myeloid-derived suppressor cells and improved tumor therapy. Life Sci. 2020 Jul 1;252:117646. doi: 10.1016/j.lfs.2020.117646. Epub 2020 Apr 7. PMID: 32272178.

 PubMed ID: 32272178

Chen ZJ, Yang SC, Liu XL, Gao Y, Dong X, Lai X, Zhu MH, Feng HY, Zhu XD, Lu Q, Zhao M, Chen HZ, Lovell JF, Fang C. Nanobowl-Supported Liposomes Improve Drug Loading and Delivery. Nano Lett. 2020 May 20. doi: 10.1021/acs.nanolett.0c00495. Epub ahead of print. PMID: 32431154.

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Harmon JS, Celingant-Copie CA, Kabinejadian F, Bull J. Lipid shell retention and selective binding capability following repeated transient acoustic microdroplet vaporization. Langmuir. 2020 May 18. doi: 10.1021/acs.langmuir.0c00320. Epub ahead of print. PMID: 32420747.

 PubMed ID: 32420747

Sergeeva O, Sergeev P, Melnikov P, Prikazchikova T, Dontsova O, Zatsepin T. Modification of Adenosine196 by Mettl3 Methyltransferase in the 5'-External Transcribed Spacer of 47S Pre-rRNA Affects rRNA Maturation. Cells. 2020 Apr 24;9(4):1061. doi: 10.3390/cells9041061. PMID: 32344536; PMCID: PMC7226171.

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Wu D, Pusuluri A, Vogus D, Krishnan V, Shields CW 4th, Kim J, Razmi A, Mitragotri S. Design principles of drug combinations for chemotherapy. J Control Release. 2020 Apr 10;323:36-46. doi: 10.1016/j.jconrel.2020.04.018. Epub ahead of print. PMID: 32283210.

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Kim B, Shin J, Wu J, Omstead DT, Kiziltepe T, Littlepage LE, Bilgicer B. Engineering peptide-targeted liposomal nanoparticles optimized for improved selectivity for HER2-positive breast cancer cells to achieve enhanced in vivo efficacy. J Control Release. 2020 Apr 8;322:530-541. doi: 10.1016/j.jconrel.2020.04.010. Epub ahead of print. PMID: 32276005.

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Cheng Q, Wei T, Farbiak L, Johnson LT, Dilliard SA, Siegwart DJ. Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing. Nat Nanotechnol. 2020 Apr;15(4):313-320. doi: 10.1038/s41565-020-0669-6. Epub 2020 Apr 6. PMID: 32251383.

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Bompard J, Rosso A, Brizuela Madrid L, Mebarek S, Blum LJ, Trunfio-Sfarghiu AT, Lollo G, Granjon T, Girard-Egrot A, Maniti O. Membrane Fluidity as a New Mean to Selectively Target Cancer Cells with Fusogenic Lipid Carriers. Langmuir. 2020 Apr 27. doi: 10.1021/acs.langmuir.0c00262. Epub ahead of print. PMID: 32338922.

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Charron D, Yousefalizadeh G, Buzza HH, Rajora MA, Chen J, Stamplecoskie KG, Zheng G. Photophysics of J-aggregating Porphyrin-lipid Photosensitizers in Liposomes-Impact of Lipid Saturation. Langmuir. 2020 Apr 27. doi: 10.1021/acs.langmuir.0c00843. Epub ahead of print. PMID: 32338515.

 PubMed ID: 32338515

Reusser TD, Song KH, Ramirez D, Benninger RK, Papadopoulou V, Borden MA. Phospholipid Oxygen Microbubbles for Image-Guided Therapy. Nanotheranostics. 2020 Feb 28;4(2):83-90. doi: 10.7150/ntno.43808. PMID: 32190535; PMCID: PMC7064740.

 PubMed ID: 32190535

Drabik D, Chodaczek G, Kraszewski S, Langner M. Mechanical Properties Determination of DMPC, DPPC, DSPC, and HSPC Solid-Ordered Bilayers. Langmuir. 2020 Apr 14;36(14):3826-3835. doi: 10.1021/acs.langmuir.0c00475. Epub 2020 Mar 24. PMID: 32176506.

 PubMed ID: 32176506

Das S, Lazenby RA, Yuan Z, White RJ, Park YC. Effect of Laser Irradiation on Reversibility and Drug Release of Light-Activatable Drug-Encapsulated Liposomes. Langmuir. 2020 Apr 7;36(13):3573-3582. doi: 10.1021/acs.langmuir.0c00215. Epub 2020 Mar 27. PMID: 32188250.

 PubMed ID: 32188250

Šimečková P, Hubatka F, Kotouček J, Turánek Knötigová P, Mašek J, Slavík J, Kováč O, Neča J, Kulich P, Hrebík D, Stráská J, Pěnčíková K, Procházková J, Diviš P, Macaulay S, Mikulík R, Raška M, Machala M, Turánek J. Gadolinium labelled nanoliposomes as the platform for MRI theranostics: in vitro safety study in liver cells and macrophages. Sci Rep. 2020 Mar 16;10(1):4780. doi: 10.1038/s41598-020-60284-z. PMID: 32179785; PMCID: PMC7075985.

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Zhang B, Li Q, Jia S, Li F, Li Q, Li J. LincRNA-EPS in biomimetic vesicles targeting cerebral infarction promotes inflammatory resolution and neurogenesis. J Transl Med. 2020 Mar 2;18(1):110. doi: 10.1186/s12967-020-02278-z. PMID: 32122362; PMCID: PMC7052981.

 PubMed ID: 32122362

Rolle F, Bincoletto V, Gazzano E, Rolando B, Lollo G, Stella B, Riganti C, Arpicco S. Coencapsulation of disulfiram and doxorubicin in liposomes strongly reverses multidrug resistance in breast cancer cells. Int J Pharm. 2020 Apr 30;580:119191. doi: 10.1016/j.ijpharm.2020.119191. Epub 2020 Mar 3. PMID: 32142738.

 PubMed ID: 32142738

Chattaraj R, Hwang M, Zemerov SD, Dmochowski IJ, Hammer DA, Lee D, Sehgal CM. Ultrasound Responsive Noble Gas Microbubbles for Applications in Image-Guided Gas Delivery. Adv Healthc Mater. 2020 Mar 24:e1901721. doi: 10.1002/adhm.201901721. Epub ahead of print. PMID: 32207250.

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Nazemidashtarjandi S, Vahedi A, Farnoud AM. Lipid Chemical Structure Modulates the Disruptive Effects of Nanomaterials on Membrane Models. Langmuir. 2020 Apr 20. doi: 10.1021/acs.langmuir.0c00295. Epub ahead of print. PMID: 32312045.

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Yu JR, Janssen M, Liang BJ, Huang HC, Fisher JP. A liposome/gelatin methacrylate nanocomposite hydrogel system for delivery of stromal cell-derived factor-1α and stimulation of cell migration. Acta Biomater. 2020 Mar 17:S1742-7061(20)30147-1. doi: 10.1016/j.actbio.2020.03.015. Epub ahead of print. PMID: 32194261.

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Zamani P, Teymouri M, Nikpoor AR, Navashenaq JG, Gholizadeh Z, Darban SA, Jaafari MR. Nanoliposomal vaccine containing long multi-epitope peptide E75-AE36 pulsed PADRE-induced effective immune response in mice TUBO model of breast cancer. Eur J Cancer. 2020 Apr;129:80-96. doi: 10.1016/j.ejca.2020.01.010. Epub 2020 Mar 4. PMID: 32145473.

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Ols S, Yang L, Thompson EA, Pushparaj P, Tran K, Liang F, Lin A, Eriksson B, Karlsson Hedestam GB, Wyatt RT, Loré K. Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity. Cell Rep. 2020 Mar 24;30(12):3964-3971.e7. doi: 10.1016/j.celrep.2020.02.111. PMID: 32209459.

 PubMed ID: 32209459

Chatzikleanthous D, Schmidt ST, Buffi G, Paciello I, Cunliffe R, Carboni F, Romano MR, O'Hagan DT, D'Oro U, Woods S, Roberts CW, Perrie Y, Adamo R. Design of a novel vaccine nanotechnology-based delivery system comprising CpGODN-protein conjugate anchored to liposomes. J Control Release. 2020 Apr 2:S0168-3659(20)30211-X. doi: 10.1016/j.jconrel.2020.04.001. Epub ahead of print. PMID: 32247804.

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Thébault CJ, Ramniceanu G, Boumati S, Michel A, Seguin J, Larrat B, Mignet N, Ménager C, Doan BT. Theranostic MRI liposomes for magnetic targeting and ultrasound triggered release of the antivascular CA4P. J Control Release. 2020 Mar 4;322:137-148. doi: 10.1016/j.jconrel.2020.03.003. Epub ahead of print. PMID: 32145266.

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Lin HC, Fan CH, Ho YJ, Yeh CK. Dual-Frequency Chirp Excitation for Passive Cavitation Imaging in the Brain. IEEE Trans Ultrason Ferroelectr Freq Control. 2020 Jan 10. doi: 10.1109/TUFFC.2020.2964786. Epub ahead of print. PMID: 31940528.

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Li N, Mai Y, Liu Q, Gou G, Yang J. Docetaxel-loaded D-α-tocopheryl polyethylene glycol-1000 succinate liposomes improve lung cancer chemotherapy and reverse multidrug resistance. Drug Deliv Transl Res. 2020 Feb 12. doi: 10.1007/s13346-020-00720-9. Epub ahead of print. PMID: 32052357.

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Gao Y, Mu Q, Zhu L, Li Z, Ho RJY. Optimizing a Novel Au-Grafted Lipid Nanoparticle Through Chelation Chemistry for High Photothermal Biologic Activity. J Pharm Sci. 2020 Feb 18:S0022-3549(20)30083-6. doi: 10.1016/j.xphs.2020.02.010. Epub ahead of print. PMID: 32081720.

 PubMed ID: 32081720

Das S, Lazenby RA, Yuan Z, White RJ, Park YC. Effect of Laser Irradiation on Reversibility and Drug Release of Light-Activatable Drug-Encapsulated Liposomes. Langmuir. 2020 Mar 27. doi: 10.1021/acs.langmuir.0c00215. Epub ahead of print. PMID: 32188250.

 PubMed ID: 32188250

Drabik D, Chodaczek G, Kraszewski S, Langner M. Mechanical Properties Determination of DMPC, DPPC, DSPC, and HSPC Solid-Ordered Bilayers. Langmuir. 2020 Mar 24. doi: 10.1021/acs.langmuir.0c00475. Epub ahead of print. PMID: 32176506.

 PubMed ID: 32176506

Osorio-Querejeta I, Carregal-Romero S, Ayerdi-Izquierdo A, Mäger I, A NL, Wood M, Egimendia A, Betanzos M, Alberro A, Iparraguirre L, Moles L, Llarena I, Möller M, Goñi-de-Cerio F, Bijelic G, Ramos-Cabrer P, Muñoz-Culla M, Otaegui D. MiR-219a-5p Enriched Extracellular Vesicles Induce OPC Differentiation and EAE Improvement More Efficiently Than Liposomes and Polymeric Nanoparticles. Pharmaceutics. 2020 Feb 21;12(2):186. doi: 10.3390/pharmaceutics12020186. PMID: 32098213; PMCID: PMC7076664.

 PubMed ID: 32098213

Zhang Y, Xiao JY, Zhu Y, Tian LJ, Wang WK, Zhu TT, Li WW, Yu HQ. Fluorescence Sensor Based on Biosynthetic CdSe/CdS Quantum Dots and Liposome Carrier Signal Amplification for Mercury Detection. Anal Chem. 2020 Mar 3;92(5):3990-3997. doi: 10.1021/acs.analchem.9b05508. Epub 2020 Feb 14. PMID: 32020800.

 PubMed ID: 32020800

Drabik D, Chodaczek G, Kraszewski S, Langner M. Mechanical properties determination of DMPC, DPPC, DSPC and HSPC solid-ordered bilayers. Langmuir. 2020 Mar 16. doi: 10.1021/acs.langmuir.0c00475. Epub ahead of print. PMID: 32176506.

 PubMed ID: 32176506

Leboeuf D, Abakumova T, Prikazchikova T, Rhym L, Anderson DG, Zatsepin TS, Piatkov KI. Downregulation of the Arg/N-degron Pathway Sensitizes Cancer Cells to Chemotherapy In Vivo. Mol Ther. 2020 Jan 21:S1525-0016(20)30053-8. doi: 10.1016/j.ymthe.2020.01.021. Epub ahead of print. PMID: 32087767.

 PubMed ID: 32087767

Ramishetti S, Hazan-Halevy I, Palakuri R, Chatterjee S, Naidu Gonna S, Dammes N, Freilich I, Kolik Shmuel L, Danino D, Peer D. A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes. Adv Mater. 2020 Jan 30:e1906128. doi: 10.1002/adma.201906128. Epub ahead of print. PMID: 31999380.

 PubMed ID: 31999380

Men W, Zhu P, Dong S, Liu W, Zhou K, Bai Y, Liu X, Gong S, Zhang S. Layer-by-layer pH-sensitive nanoparticles for drug delivery and controlled release with improved therapeutic efficacy in vivo. Drug Deliv. 2020 Dec;27(1):180-190. doi: 10.1080/10717544.2019.1709922. PMID: 31924103.

 PubMed ID: 31924103

Asasutjarit R, Managit C, Phanaksri T, Treesuppharat W, Fuongfuchat A. Formulation development and in vitro evaluation of transferrin-conjugated liposomes as a carrier of ganciclovir targeting the retina. Int J Pharm. 2020 Jan 25;577:119084. doi: 10.1016/j.ijpharm.2020.119084. Epub ahead of print. PMID: 31988033.

 PubMed ID: 31988033

Talló K, Bosch M, Pons R, Cocera M, López O. Preparation and characterization of a supramolecular hydrogel made of phospholipids and oleic acid with a high water content. J Mater Chem B. 2020 Jan 7;8(1):161-167. doi: 10.1039/c9tb01599j. Epub 2019 Nov 29. PMID: 31782478.

 PubMed ID: 31782478

Ye S , Liu Y , Lu Y , Ji Y , Mei L , Yang M , Gong X , Gu Q , Li D , Yang F , Li CJ . Cyclic RGD functionalized liposomes targeted to activated platelets for thrombosis dual-mode magnetic resonance imaging. J Mater Chem B. 2020 Jan 22;8(3):447-453. doi: 10.1039/c9tb01834d. PMID: 31833530.

 PubMed ID: 31833530

Molinaro R, Martinez JO, Zinger A, De Vita A, Storci G, Arrighetti N, De Rosa E, Hartman KA, Basu N, Taghipour N, Corbo C, Tasciotti E. Leukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma. Biomater Sci. 2020 Jan 1;8(1):333-341. doi: 10.1039/c9bm01766f. Epub 2019 Nov 12. PMID: 31714542.

 PubMed ID: 31714542

Kari OK , Ndika J , Parkkila P , Louna A , Lajunen T , Puustinen A , Viitala T , Alenius H , Urtti A . In situ analysis of liposome hard and soft protein corona structure and composition in a single label-free workflow. Nanoscale. 2020 Jan 23;12(3):1728-1741. doi: 10.1039/c9nr08186k. PMID: 31894806.

 PubMed ID: 31894806

Browning RJ, Aron M, Booth A, Rademeyer P, Wing S, Brans V, Shrivastava S, Carugo D, Stride E. Spectral Imaging for Microbubble Characterization. Langmuir. 2020 Jan 21;36(2):609-617. doi: 10.1021/acs.langmuir.9b03828. Epub 2020 Jan 9. PMID: 31855435.

 PubMed ID: 31855435

Sou K, Chan LY, Arai S, Lee CK. Highly cooperative fluorescence switching of self-assembled squaraine dye at tunable threshold temperatures using thermosensitive nanovesicles for optical sensing and imaging. Sci Rep. 2019 Nov 29;9(1):17991. doi: 10.1038/s41598-019-54418-1. PMID: 31784685; PMCID: PMC6884458.

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Hussain MT, Forbes N, Perrie Y, Malik KP, Duru C, Matejtschuk P. Freeze-drying cycle optimization for the rapid preservation of protein-loaded liposomal formulations. Int J Pharm. 2020 Jan 5;573:118722. doi: 10.1016/j.ijpharm.2019.118722. Epub 2019 Nov 6. PMID: 31705976.

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Stras S, Howe A, Prasad A, Salerno D, Bhatavdekar O, Sofou S. Growth of Metastatic Triple-Negative Breast Cancer Is Inhibited by Deep Tumor-Penetrating and Slow Tumor-Clearing Chemotherapy: The Case of Tumor-Adhering Liposomes with Interstitial Drug Release. Mol Pharm. 2020 Jan 6;17(1):118-131. doi: 10.1021/acs.molpharmaceut.9b00812. Epub 2019 Dec 23. PMID: 31825626.

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Samaddar S, Mazur J, Boehm D, Thompson DH. Development And In Vitro Characterization Of Bladder Tumor Cell Targeted Lipid-Coated Polyplex For Dual Delivery Of Plasmids And Small Molecules. Int J Nanomedicine. 2019 Dec 4;14:9547-9561. doi: 10.2147/IJN.S225172. PMID: 31824150; PMCID: PMC6900316.

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Liu H, Liu S, Liang Y, Deng Z, Wang Y, Yan F. Real-Time Imaging Tracking of Mesenchymal Stem Cells Labeled with Lipid-Poly(lactic-co-glycolic acid) Nanobubbles. J Biomed Nanotechnol. 2019 Nov 1;15(11):2271-2280. doi: 10.1166/jbn.2019.2852. PMID: 31847941.

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Li Y, Zhai Y, Liu W, Zhang K, Liu J, Shi J, Zhang Z. Ultrasmall nanostructured drug based pH-sensitive liposome for effective treatment of drug-resistant tumor. J Nanobiotechnology. 2019 Nov 29;17(1):117. doi: 10.1186/s12951-019-0550-7. PMID: 31783863; PMCID: PMC6884872.

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Wu M, Song Z, Zhang S, Dan Q, Tang C, Peng C, Liang Y, Zhang L, Wang H, Li Y. Local Tumor Ischemia-Reperfusion Mediated By Ultrasound-Targeted Microbubble Destruction Enhances The Anti-Tumor Efficacy Of Doxorubicin Chemotherapy. Cancer Manag Res. 2019 Nov 5;11:9387-9395. doi: 10.2147/CMAR.S225607. eCollection 2019.

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Ciancone M, Bellec N, Cammas-Marion S, Dolet A, Vray D, Varray F, Le Goff-Gaillard C, Le Goff X, Arlot-Bonnemains Y, Camerel F. Liposomes Containing Nickel-Bis(dithiolene) Complexes for Photothermal Theranostics. Langmuir. 2019 Nov 26;35(47):15121-15130. doi: 10.1021/acs.langmuir.9b01296. Epub 2019 Nov 13.

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Reis A, Soares S, Sousa CF, Dias R, Gameiro P, Soares S, de Freitas V. Interaction of polyphenols with model membranes: Putative implications to mouthfeel perception. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183133. doi: 10.1016/j.bbamem.2019.183133. Epub 2019 Nov 28.

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Peng PC, Hong RL, Tsai T, Chen CT. Co-Encapsulation of Chlorin e6 and Chemotherapeutic Drugs in a PEGylated Liposome Enhance the Efficacy of Tumor Treatment: Pharmacokinetics and Therapeutic Efficacy. Pharmaceutics. 2019 Nov 17;11(11). pii: E617. doi: 10.3390/pharmaceutics11110617.

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Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vázquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT. Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity. 2019 Nov 19;51(5):915-929.e7. doi: 10.1016/j.immuni.2019.10.008. Epub 2019 Nov 12.

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Punjabi M, Xu L, Ochoa-Espinosa A, Kosareva A, Wolff T, Murtaja A, Broisat A, Devoogdt N, Kaufmann BA. Ultrasound Molecular Imaging of Atherosclerosis With Nanobodies: Translatable Microbubble Targeting Murine and Human VCAM (Vascular Cell Adhesion Molecule) 1. Arterioscler Thromb Vasc Biol. 2019 Dec;39(12):2520-2530. doi: 10.1161/ATVBAHA.119.313088. Epub 2019 Oct 10.

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Veiga N, Goldsmith M, Diesendruck Y, Ramishetti S, Rosenblum D, Elinav E, Behlke MA, Benhar I, Peer D. Leukocyte-specific siRNA delivery revealing IRF8 as a potential anti-inflammatory target. J Control Release. 2019 Oct 18;313:33-41. doi: 10.1016/j.jconrel.2019.10.001. [Epub ahead of print]

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Chung CHY, Cui B, Song R, Liu X, Xu X, Yao S. Scalable Production of Monodisperse Functional Microspheres by Multilayer Parallelization of High Aspect Ratio Microfluidic Channels. Micromachines (Basel). 2019 Sep 10;10(9). pii: E592. doi: 10.3390/mi10090592.

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Khan AA, Maitz C, Quanyu C, Hawthorne F. BNCT induced immunomodulatory effects contribute to mammary tumor inhibition. PLoS One. 2019 Sep 3;14(9):e0222022. doi: 10.1371/journal.pone.0222022. eCollection 2019.

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Chen KTJ, Anantha M, Leung AWY, Kulkarni JA, Militao GGC, Wehbe M, Sutherland B, Cullis PR, Bally MB. Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use. Drug Deliv Transl Res. 2019 Sep 3. doi: 10.1007/s13346-019-00674-7. [Epub ahead of print]

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Kono Y, Gogatsubo S, Ohba T, Fujita T. Enhanced macrophage delivery to the colon using magnetic lipoplexes with a magnetic field. Drug Deliv. 2019 Dec;26(1):935-943. doi: 10.1080/10717544.2019.1662515.

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Shang H, Wu B, Liang X, Sun Y, Han X, Zhang L, Wang Q, Cheng W. Evaluation of therapeutic effect of targeting nanobubbles conjugated with NET-1 siRNA by shear wave elastography: an in vivo study of hepatocellular carcinoma bearing mice model. Drug Deliv. 2019 Dec;26(1):944-951. doi: 10.1080/10717544.2019.1667450.

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Yuan Z, Demith A, Stoffel R, Zhang Z, Park YC. Light-activated doxorubicin-encapsulated perfluorocarbon nanodroplets for on-demand drug delivery in an in vitro angiogenesis model: Comparison between perfluoropentane and perfluorohexane. Colloids Surf B Biointerfaces. 2019 Sep 7;184:110484. doi: 10.1016/j.colsurfb.2019.110484. [Epub ahead of print]

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Faria MJ, Machado R, Ribeiro A, Gonçalves H, Real Oliveira MECD, Viseu T, das Neves J, Lúcio M. Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention. Pharmaceutics. 2019 Sep 18;11(9). pii: E485. doi: 10.3390/pharmaceutics11090485.

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Stefanick JF, Omstead DT, Ashley JD, Deak PE, Mustafaoglu N, Kiziltepe T, Bilgicer B. Optimizing design parameters of a peptide targeted liposomal nanoparticle in an in vivo multiple myeloma disease model after initial evaluation in vitro. J Control Release. 2019 Aug 29;311-312:190-200. doi: 10.1016/j.jconrel.2019.08.033. [Epub ahead of print]

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Zhang W, Böttger R, Qin Z, Kulkarni JA, Vogler J, Cullis PR, Li SD. Phospholipid-Free Small Unilamellar Vesicles for Drug Targeting to Cells in the Liver. Small. 2019 Oct;15(43):e1901782. doi: 10.1002/smll.201901782. Epub 2019 Sep 6.

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Oddo L, Paradossi G, Cerroni B, Ben-Harush C, Ariel E, Di Meco F, Ram Z, Grossman R. In Vivo Biodistribution of Engineered Lipid Microbubbles in Rodents. ACS Omega. 2019 Aug 8;4(8):13371-13381. doi: 10.1021/acsomega.9b01544. eCollection 2019 Aug 20.

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Cheng V, Kimball DR, Conboy DJC. Determination of the Rate-Limiting Step in Fatty Acid Transport. J Phys Chem B. 2019 Aug 22;123(33):7157-7168. doi: 10.1021/acs.jpcb.9b05162. Epub 2019 Aug 12.

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Demetriou E, Story HE, Bofinger R, Hailes HC, Tabor AB, Golay X. Effect of Liposomal Encapsulation on the Chemical Exchange Properties of Diamagnetic CEST Agents. J Phys Chem B. 2019 Aug 26. doi: 10.1021/acs.jpcb.9b02280. [Epub ahead of print]

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DeBoer MD. Assessing and Managing the Metabolic Syndrome in Children and Adolescents. Nutrients. 2019 Aug 2;11(8). pii: E1788. doi: 10.3390/nu11081788.

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Wang Z, Zhao K, Zhang Y, Duan X, Zhao Y. Anti-GPC3 Antibody Tagged Cationic Switchable Lipid-Based Nanoparticles for the Co-Delivery of Anti-miRNA27a And Sorafenib in Liver Cancers. Pharm Res. 2019 Aug 8;36(10):145. doi: 10.1007/s11095-019-2669-5.

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Wang Z, Zhao K, Zhang Y, Duan X, Zhao Y. Anti-GPC3 Antibody Tagged Cationic Switchable Lipid-Based Nanoparticles for the Co-Delivery of Anti-miRNA27a And Sorafenib in Liver Cancers. Pharm Res. 2019 Aug 8;36(10):145. doi: 10.1007/s11095-019-2669-5.

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Harmon JS, Kabinejadian F, Seda R, Fabiilli ML, Kuruvilla S, Kuo CC, Greve JM, Fowlkes JB, Bull JL. Minimally invasive gas embolization using acoustic droplet vaporization in a rodent model of hepatocellular carcinoma. Sci Rep. 2019 Jul 30;9(1):11040. doi: 10.1038/s41598-019-47309-y.

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Matusewicz L, Filip-Psurska B, Psurski M, Tabaczar S, Podkalicka J, Wietrzyk J, Ziółkowski P, Czogalla A, Sikorski AF. EGFR-targeted immunoliposomes as a selective delivery system of simvastatin, with potential use in treatment of triple-negative breast cancers. Int J Pharm. 2019 Oct 5;569:118605. doi: 10.1016/j.ijpharm.2019.118605. Epub 2019 Aug 7.

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Hamano N, Böttger R, Lee SE, Yang Y, Kulkarni JA, Ip S, Cullis PR, Li SD. Robust Microfluidic Technology and New Lipid Composition for Fabrication of Curcumin-Loaded Liposomes: Effect on the Anticancer Activity and Safety of Cisplatin. Mol Pharm. 2019 Sep 3;16(9):3957-3967. doi: 10.1021/acs.molpharmaceut.9b00583. Epub 2019 Aug 16.

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Einhäupl P, Krook J, Svensson N, Van Acker K, Van Passel S. Eliciting stakeholder needs - An anticipatory approach assessing enhanced landfill mining. Waste Manag. 2019 Oct;98:113-125. doi: 10.1016/j.wasman.2019.08.009. Epub 2019 Aug 21.

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Kanamala M, Palmer BD, Jamieson SM, Wilson WR, Wu Z. Dual pH-sensitive liposomes with low pH-triggered sheddable PEG for enhanced tumor-targeted drug delivery. Nanomedicine (Lond). 2019 Aug;14(15):1971-1989. doi: 10.2217/nnm-2018-0510. Epub 2019 Jul 29.

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Liu J, Chen Y, Wang G, Jin Q, Sun Z, Lv Q, Wang J, Yang Y, Zhang L, Xie M. Improving acute cardiac transplantation rejection therapy using ultrasound-targeted FK506-loaded microbubbles in rats. Biomater Sci. 2019 Sep 1;7(9):3729-3740. doi: 10.1039/c9bm00301k. Epub 2019 Aug 12.

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Takechi-Haraya Y, Goda Y, Izutsu K, Sakai-Kato K. Improved Atomic Force Microscopy Stiffness Measurements of Nanoscale Liposomes by Cantilever Tip Shape Evaluation. Anal Chem. 2019 Aug 20;91(16):10432-10440. doi: 10.1021/acs.analchem.9b00250. Epub 2019 Aug 7.

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Huang ZR, Tipparaju SK, Kirpotin DB, Pien C, Kornaga T, Noble CO, Koshkaryev A, Tran J, Kamoun WS, Drummond DC. Formulation optimization of an ephrin A2 targeted immunoliposome encapsulating reversibly modified taxane prodrugs. J Control Release. 2019 Sep 28;310:47-57. doi: 10.1016/j.jconrel.2019.08.006. Epub 2019 Aug 7.

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Melo M, Porter E, Zhang Y, Silva M, Li N, Dobosh B, Liguori A, Skog P, Landais E, Menis S, Sok D, Nemazee D, Schief WR, Weiss R, Irvine DJ. Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles. Mol Ther. 2019 Aug 19. pii: S1525-0016(19)30367-3. doi: 10.1016/j.ymthe.2019.08.007. [Epub ahead of print]

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