850356 | 4ME 16:0 PC

1,2-diphytanoyl-sn-glycero-3-phosphocholine


Chloroform

Size SKU Packaging Price
25mg 850356C-25mg 850356C-25mg 1 x 25mg 10mg/mL 2.5mL $108.00
200mg 850356C-200mg 850356C-200mg 2 x 100mg 25mg/mL 4mL $342.00
500mg 850356C-500mg 850356C-500mg 1 x 500mg 25mg/mL 20mL $730.00

Powder

Size SKU Packaging Price
25mg 850356P-25mg 850356P-25mg 1 x 25mg $108.00
200mg 850356P-200mg 850356P-200mg 1 x 200mg $342.00
500mg 850356P-500mg 850356P-500mg 1 x 500mg $730.00
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4ME 16:0 PC

4ME 16:0 PC

1,2-diphytanoyl-sn-glycero-3-phosphocholine

Lipids containing diphytanoyl fatty acid chains have been used to produce stable planar lipid membranes (see References). Diphytanoyl phosphatidylcholine does not exhibit a detectable gel to liquid crystalline phase transition from -120°C to +120°C.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C48H96NO8P
Percent Composition
C 68.13%, H 11.43%, N 1.66%, O 15.12%, P 3.66%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
207131-40-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
846.252
Exact Mass
845.687
Synonyms
<p>1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholinePC(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))</p>

Sacconi A, Tadini-Buoninsegni F, Tiribilli B, Margheri G. A Comparative Study of Phosphatidylcholine versus Phosphatidylserine-based Solid Supported Membranes for the Preparation of Liposome-Rich Interfaces. Langmuir. 2018 Sep 14. doi: 10.1021/acs.langmuir.8b02397. [Epub ahead of print]

PubMed ID: 30217106

Burden DL, Kim D, Cheng W, Chandler Lawler E, Dreyer DR, Burden LK. Mechanically Enhancing Planar Lipid Bilayers with a Minimal Actin Cortex. Langmuir. 2018 Aug 27. doi: 10.1021/acs.langmuir.8b01847. [Epub ahead of print]

PubMed ID: 30149716

Beltramo PJ, Scheidegger L, Vermant J. Toward Realistic Large-Area Cell Membrane Mimics: Excluding Oil, Controlling Composition, and Including Ion Channels. Langmuir. 2018 May 14. doi: 10.1021/acs.langmuir.8b00837.

PubMed ID: 29715042

Lindsey, H., N.O. Petersen, and S.I. Chan. (1979). Physicochemical characterization of 1,2-diphytanoyl-sn-glycero-3-phosphocholine in model membrane systems. Biochim Biophys Acta 555:147-67. [PubMed]

PubMed ID: 476096

Villar, G., A.D. Graham, and H. Bayley. (2013). A tissue-like printed material. Science 340:48-52. [PubMed]

PubMed ID: 23559243

Pan, J., X. Cheng, F.A. Heberle, B. Mostofian, N. Kucerka, P. Drazba, and J. Katsaras. (2012). Interactions between Ether Phospholipids and Cholesterol As Determined by Scattering and Molecular Dynamics Simulations. J Phys Chem B [PubMed]

PubMed ID: 23199292

Tristram-Nagle, S., Kim, D.J., Akhunzada, N., Kucerka, N., Mathai, J.C., Katsaras, J., Zeidel, M., Nagle, J.F. (2010) Structure and water permeability of fully hydrated diphytanoylPC. Chem Phys Lipids.163:630-7. [PubMed]

PubMed ID: 20447383

Redwood, W.R., Pfeiffer, F.R., Weisbach, J.A., Thompson, T.E. (1971) Physical properties of bilayer membranes formed from a synthetic saturated phospholipid in n-decane. Biochim Biophys Acta.233:1-6. [PubMed]

PubMed ID: 5579131