850355 | 16:0 PC (DPPC)



Size SKU Packaging Price
25mg 850355C-25mg 850355C-25mg 1 x 25mg 10mg/mL 2.5mL $45.25
200mg 850355C-200mg 850355C-200mg 2 x 100mg 25mg/mL 4mL $72.00
500mg 850355C-500mg 850355C-500mg 1 x 500mg 25mg/mL 20mL $120.00
1g 850355C-1g 850355C-1g 2 x 500mg 25mg/mL 20mL $170.00


Size SKU Packaging Price
25mg 850355P-25mg 850355P-25mg 1 x 25mg $45.25
200mg 850355P-200mg 850355P-200mg 1 x 200mg $72.00
500mg 850355P-500mg 850355P-500mg 1 x 500mg $120.00
1g 850355P-1g 850355P-1g 1 x 1g $170.00
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16:0 PC (DPPC)

16:0 PC (DPPC)


The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Light Sensitive
Molecular Formula
Percent Composition
C 65.45%, H 10.98%, N 1.91%, O 17.44%, P 4.22%
1 Year
Storage Temperature
CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
Exact Mass
<p>1,2-dihexadecanoyl-sn-glycero-3-phosphocholine</p> <p>DPPC</p> <p>PC(16:0/16:0)</p>

Mudassar Mumtaz Virk, Benedikt Hofmann, and Erik Reimhult. Formation and Characteristics of Lipid-Blended Block Copolymer Bilayers on a Solid Support Investigated by Quartz Crystal Microbalance and Atomic Force Microscopy. Langmuir, Articles ASAP (As Soon As Publishable)

Virk MM, Hofmann B, Reimhult E. Formation and Characteristics of Lipid Blended Block Copolymer Bilayers on Solid Support Investigated by Quartz Crystal Microbalance and Atomic Force Microscope. Langmuir. 2018 Dec 23. doi: 10.1021/acs.langmuir.8b03597. [Epub ahead of print]

PubMed ID: 30580525

Kurniawan J, Ventrici de Souza JF, Dang AT, Liu GY, Kuhl TL. Preparation and Characterization of Solid Supported Lipid Bilayers Formed by Langmuir-Blodgett Deposition - a Tutorial. Langmuir. 2018 Nov 22. doi: 10.1021/acs.langmuir.8b03504. [Epub ahead of print]

PubMed ID: 30465730

Shi D, Liu X, Counil C, Krafft MP. Fluorocarbon Exposure Mode Markedly Affects Phospholipid Monolayer Behavior at the Gas/Liquid Interface. Impact on Size and Stability of Microbubbles. Langmuir. 2018 Dec 14. doi: 10.1021/acs.langmuir.8b03546. [Epub ahead of print]

PubMed ID: 30548072

Saptarshi Chakraborty, Akram Abbasi, Geoffrey D. Bothun, Michihiro Nagao, and Christopher L. Kitchens. Phospholipid Bilayer Softening due to Hydrophobic Gold Nanoparticle Inclusions. Langmuir, Just Accepted Manuscript. DOI: 10.1021/acs.langmuir.8b02553. Publication Date (Web): October 16, 2018

Hood ED, Greineder CF, Shuvaeva T, Walsh L, Villa CH, Muzykantov VR. Vascular targeting of radiolabeled liposomes with bio-orthogonally conjugated ligands: single chain fragments provide higher specificity than antibodies. Bioconjug Chem. 2018 Sep 21. doi: 10.1021/acs.bioconjchem.8b00564. [Epub ahead of print]

PubMed ID: 30240185

Becher S, Esch P, Heiles S. Relative Quantification of Phosphatidylcholine sn-Isomers Using Positive Doubly Charged Lipid-Metal Ion Complexes. Anal Chem. 2018 Sep 21. doi: 10.1021/acs.analchem.8b02731. [Epub ahead of print]

PubMed ID: 30199242

Wang Q, London E. Lipid Structure and Composition Control Consequences of Interleaflet Coupling in Asymmetric Vesicles. Biophys J. 2018 Jul 19. pii: S0006-3495(18)30814-2. doi: 10.1016/j.bpj.2018.07.011. [Epub ahead of print]

PubMed ID: 30082033

Almeida PF, Carter FE, Kilgour KM, Raymonda MH, Tejada E. Heat Capacity of DPPC/Cholesterol Mixtures: Comparison of Single Bilayers with Multibilayers and Simulations. Langmuir. 2018 Aug 8. doi: 10.1021/acs.langmuir.8b01774. [Epub ahead of print]

PubMed ID: 30088940

Peters BJ, Van Cleave C, Haase AA, Hough JPB, Giffen-Kent KA, Cardiff GM, Sostarecz AG, Crick DC, Crans DC. Structure Dependence of Pyridine and Benzene Derivatives on Interactions with Model Membranes. Langmuir. 2018 Jul 19. doi: 10.1021/acs.langmuir.8b01661. [Epub ahead of print]

PubMed ID: 29958493

Mamusa M, Salvatore A, Berti D. Structural Modifications of DPPC Bilayers upon Inclusion of an Antibacterial Cationic Bolaamphiphile. Langmuir. 2018 Jul 18. doi: 10.1021/acs.langmuir.8b01689. [Epub ahead of print]

PubMed ID: 29976066

Kassenböhmer R, Heeger M, Dwivedi M, Körsgen M, Tyler BJ, Galla HJ, Arlinghaus HF. 3D Molecular ToF-SIMS Imaging of Artificial Lipid Membranes Using a Discriminant Analysis-Based Algorithm. Langmuir. 2018 Jul 17. doi: 10.1021/acs.langmuir.8b01253. [Epub ahead of print]

PubMed ID: 29969039

Xu L, Zuo YY. Reversible Phase Transitions in the Phospholipid Monolayer. Langmuir. 2018 Jul 3. doi: 10.1021/acs.langmuir.8b01544. [Epub ahead of print]

PubMed ID: 29969270

Domínguez Pardo JJ, Koorengevel MC, Uwugiaren N, Weijers J, Kopf AH, Jahn H, van Walree CA, van Steenbergen MJ, Killian JA. Membrane Solubilization by Styrene-Maleic Acid Copolymers: Delineating the Role of Polymer Length. Biophys J. 2018 Jul 3;115(1):129-138. doi: 10.1016/j.bpj.2018.05.032.

PubMed ID: 29972804

Ahmed S, Matsumura K, Hamada T. Hydrophobic Polyampholytes and Nonfreezing Cold Temperature Stimulate Internalization of Au Nanoparticles to Zwitterionic Liposomes. Langmuir. 2018 Jul 6. doi: 10.1021/acs.langmuir.8b00920. [Epub ahead of print]

PubMed ID: 29936842

Parkkila P, Elderdfi M, Bunker A, Viitala T. Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements. Langmuir. 2018 Jun 25. doi: 10.1021/acs.langmuir.8b01259. [Epub ahead of print]

PubMed ID: 29894192

Taylor GJ, Heberle FA, Seinfeld JS, Katsaras J, Collier CP , Sarles SA. Capacitive Detection of Low-Enthalpy, Higher-Order Phase Transitions in Synthetic and Natural Composition Lipid Membranes. Langmuir. 2017 Sep 26;33(38):10016-10026. doi: 10.1021/acs.langmuir.7b02022. Epub 2017 Sep 5.

PubMed ID: 28810118

Parkkila P, Elderdfi M, Bunker A, Viitala T. Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements. Langmuir. 2018 Jun 25. doi: 10.1021/acs.langmuir.8b01259. [Epub ahead of print]

PubMed ID: 29894192

Kot EF, Arseniev AS, Mineev KS. On the behavior of most widely spread lipids in isotropic bicelles. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01454. [Epub ahead of print]

PubMed ID: 29924628

Yang M, Wang K, Lin J, Wang L, Wei F, Zhu JT, Zheng W, Shen L. Gel Phase Membrane Retards Amyloid β-peptide (1-42) Fibrillation by Restricting Slaved Diffusion of Peptides on Lipid Bilayers. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01315. [Epub ahead of print]

PubMed ID: 29925241

Parkkila P, Elderdfi M, Bunker A, Viitala T. Biophysical characterization of supported lipid bilayers using parallel dual-wavelength surface plasmon resonance and quartz crystal microbalance measurements. Langmuir. 2018 Jun 12. doi: 10.1021/acs.langmuir.8b01259. [Epub ahead of print]

PubMed ID: 29894192

Steer D, Leung SSW, Meiselman H, Topgaard D, Leal C. Structure of Lung-Mimetic Multilamellar Bodies with Lipid Compositions Relevant in Pneumonia. Langmuir. 2018 Jun 14. doi: 10.1021/acs.langmuir.8b01359. [Epub ahead of print]

PubMed ID: 29847137

Wang M, Liu Z, Zhan W. Janus Liposomes: Gel-Assisted Formation and Bioaffinity-Directed Clustering. Langmuir. 2018 Jun 12. doi: 10.1021/acs.langmuir.8b00798. [Epub ahead of print]

PubMed ID: 29852065

Terakosolphan W, Trick JL, Royall PG, Rogers SE, Lamberti O, Lorenz CD, Forbes B, Harvey RD. Glycerol solvates DPPC headgroups and localises in the interfacial regions of model pulmonary interfaces altering bilayer structure. Langmuir. 2018 May 8. doi: 10.1021/acs.langmuir.8b00866.

Kenneth P. Mineart, Shrinivas Venkataraman, Yi Yan Yang, James L. Hedrick and Vivek M. Prabhu. Fabrication and Characterization of Hybrid Stealth Liposomes. Macromolecules, Article ASAP

Xu L, Bosiljevac G, Yu K, Zuo YY Melting of the Dipalmitoylphosphatidylcholine Monolayer. Langmuir. 2018 Apr 2. doi: 10.1021/acs.langmuir.8b00579.

PubMed ID: 29565138

Oropeza-Guzman E, Ruiz-Suárez JC. Dehydration/Rehydration Cycles for Mixing Phospholipids without the Use of Organic Solvents. Langmuir. 2018 May 29. doi: 10.1021/acs.langmuir.8b00799. [Epub ahead of print]

PubMed ID: 29779384

Yu Q, Sun J, Huang S, Chang H, Bai Q, Chen YX, Liang D. Inward Budding and Endocytosis of Membranes Regulated by de Novo Designed Peptides. Langmuir. 2018 May 16. doi: 10.1021/acs.langmuir.8b00882. [Epub ahead of print]

PubMed ID: 29733597

Liu X, Li X, Xu W, Zhang X, Huang Z, Wang F, Liu J. Sub-Angstrom Gold Nanoparticle/Liposome Interfaces Controlled by Halides. Langmuir. 2018 May 21. doi: 10.1021/acs.langmuir.8b01138.

PubMed ID: 29741377

Gonçalves da Silva AMPS. Interaction of Hydrophobic Ionic Liquids with Lipids in Langmuir Monolayers. Langmuir. 2018 Apr 3;34(13):3797-3805. doi: 10.1021/acs.langmuir.7b04164. Epub 2018 Mar 20.

PubMed ID: 29518336

Nanoroughness Strongly Impacts Lipid Mobility in Supported Membranes Florence Blachon†, Frédéric Harb‡, Bogdan Munteanu§, Agnès Piednoir†, Rémy Fulcrand†, Thierry Charitat∥, Giovanna Fragneto⊥, Olivier Pierre-Louis†, Bernard Tinland#, and Jean-Paul Rieu*† Langmuir, Article ASAP

PubMed ID: 28219008

Calcium and Zinc Differentially Affect the Structure of Lipid Membranes Norbert Kučerka*†‡ , Ermuhammad Dushanov§, Kholmirzo T. Kholmurodov‡∥, John Katsaras⊥#∇, and Daniela UhríkovᆠLangmuir, Article ASAP

PubMed ID: 28277666

Interfacial Structure and Hydration of 3D Lipid Monolayers in Aqueous Solution, Halil I. Okur , Yixing Chen, Nikolay Smolentsev, Evangelia Zdrali, and Sylvie Roke, Phys. Chem. B, Article ASAP

PubMed ID: 28263601

Preferential Adsorption of l-Histidine onto DOPC/Sphingomyelin/3β-[N-(N′,N′-dimethylaminoethane)carbamoyl]cholesterol Liposomes in the Presence of Chiral Organic Acids Keishi Suga, Atsushi Tauchi, Takaaki Ishigami, Yukihiro Okamoto, and Hiroshi Umakoshi* Langmuir, Article ASAP

PubMed ID: 28272888

Matthew Ryan Preiss, Ashley Hart, Christopher Kitchens, and Geoffrey D. Bothun. Hydrophobic Nanoparticles Modify the Thermal Release Behavior of Liposomes. J. Phys. Chem. B, Article ASAP. DOI: 10.1021/acs.jpcb.7b01702

PubMed ID: 28441023

Ling Han, Luis C. Morales, Michele R. Richards, Elena N. Kitova, Simonetta Sipione and John S. Klassen. Investigating the Influence of Membrane Composition on Protein–Glycolipid Binding Using Nanodiscs and Proxy Ligand Electrospray Ionization Mass Spectrometry. Anal. Chem., Article ASAP

PubMed ID: 28768095

Janich, C., Hadicke, A., Bakowsky, U., Brezesinski, G., and Wolk, C. Interaction of DNA with Cationic Lipid Mixtures-Investigation at Langmuir Lipid Monolayers. Langmuir, 2017 Article ASAP.

PubMed ID: 28873311

Nuria Roldan,Thomas K.M. Nyholm,J. Peter Slotte,Jesús Pérez-Gil,Begoña García-Álvarez. (2016). Effect of Lung Surfactant Protein SP-C and SP-C-Promoted Membrane Fragmentation on Cholesterol Dynamics. Biophysical Journal 111(8):1703-1713.

PubMed ID: 27760357

Phosphatidylserine Allows Observation of the Calcium–Myristoyl Switch of Recoverin and Its Preferential Binding Philippe Calvez, Thaís F. Schmidt, Line Cantin, Kristina Klinker and Christian Salesse J. Am. Chem. Soc., Article ASAP Publication Date (Web): October 11, 2016

PubMed ID: 27689444

Zuo, Y.Y., R. Chen, X.J. Wang, J. Yang, Z. Policova, and A.W. Neumann. (2016). Phase Transitions in Dipalmitoylphosphatidylcholine Monolayers. Langmuir

PubMed ID: 27479299

Qiao, B.F. and M. Olvera de la Cruz. (2013). Driving force for crystallization of anionic lipid membranes revealed by atomistic simulations. J Phys Chem B 117:5073-80.

PubMed ID: 23565965

Krause, M.R., S. Turkyilmaz, and S.L. Regen. (2013). Surface Occupancy Plays a Major Role in Cholesterol's Condensing Effect. Langmuir 29:10303-6.

PubMed ID: 23902525

Kurniawan, Y., C. Scholz, and G.D. Bothun. (2013). n-Butanol Partitioning into Phase-Separated Heterogeneous Lipid Monolayers. Langmuir 29:10817-23.

PubMed ID: 23888902

Suga, K. and H. Umakoshi. (2013). Detection of Nanosized Ordered Domains in DOPC/DPPC and DOPC/Ch Binary Lipid Mixture Systems of Large Unilamellar Vesicles Using a TEMPO Quenching Method. Langmuir

PubMed ID: 23506052

Lonnfors, M., O. Langvik, A. Bjorkbom, and J.P. Slotte. (2013). Cholesteryl Phosphocholine - A Study on Its Interactions with Ceramides and Other Membrane Lipids. Langmuir

PubMed ID: 23356741

Choi, S.Q., S. Steltenkamp, J.A. Zasadzinski, and T.M. Squires. (2011). Active microrheology and simultaneous visualization of sheared phospholipid monolayers. Nat Commun 2:312

PubMed ID: 21587229

Marquardt, D., Herberle, F.A., Miti, T., Eicher, B., London, E., Katsaras, J., Pabst, G. (2017). 1H NMR Shows Slow Phospholipid Flip-Flop in Gel and Fluid Bilayers. Langmuir.

PubMed ID: 28106399

Phase Composition Control in Microsphere-Supported Biomembrane Systems Eric S. Fried, Yue-ming Li, and Malcolm Lane Gilchrist Langmuir, Just Accepted Manuscript DOI: 10.1021/acs.langmuir.6b04150 Publication Date (Web): February 15, 2017 Copyright © 2017 American Chemical Society

PubMed ID: 28198634

Effects of Surface Charges on the Bactericide Activity of CdTe/ZnS Quantum Dots: A Cell Membrane Disruption Perspective, Lu Lai, Sheng-Jin Li, Jing Feng, Ping Mei, Zhao-Hua Ren, Yan-Ling Chang, and Yi Liu Langmuir, Article ASAP, DOI: 10.1021/acs.langmuir.7b00173

PubMed ID: 28178781

Yixing Chen, Halil I. Okur, Cornelis Lütgebaucks, and Sylvie Roke. Zwitterionic and charged lipids form remarkably different structures on nanoscale oil droplets in aqueous solution. Langmuir, Just Accepted Manuscript.

PubMed ID: 29019694

Mumtaz Virk M, Reimhult E. Phospholipase A2-Induced Degradation and Release from Lipid-Containing Polymersomes. Langmuir. 2017 Dec 27. doi: 10.1021/acs.langmuir.7b03893.

PubMed ID: 29231739

Enoki TA, Moreira-Silva I, Lorenzon EN, Cilli EM, Perez KR, Riske KA, Lamy MT. Antimicrobial Peptide K0-W6-Hya1 Induces Stable Structurally Modified Lipid Domains in Anionic Membranes. Langmuir. 2018 Jan 22. doi: 10.1021/acs.langmuir.7b03408.

PubMed ID: 29284086

Ausili A, Torrecillas A, deGodos AM, Corbalan-Garcia S, Gomez-Fernandez JC. The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes. Langmuir. 2018 Feb 15. doi: 10.1021/acs.langmuir.7b04142.

PubMed ID: 29447442

Eleftheriadis GK, Akrivou M, Bouropoulos N, Tsibouklis J, Vizirianakis IS, Fatouros DG. Polymer-lipid microparticles for pulmonary delivery. Langmuir. 2018 Feb 27. doi: 10.1021/acs.langmuir.7b03645.

PubMed ID: 29486562

Kot EF, Goncharuk SA, Arseniev AS, Mineev KS. Phase Transitions in Small Isotropic Bicelles. Langmuir. 2018 Mar 6. doi: 10.1021/acs.langmuir.7b03610.

PubMed ID: 29486112