850345 | 14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine


Powder

Size SKU Packaging Price
25mg 850345P-25mg 850345P-25mg 1 x 25mg $43.00
200mg 850345P-200mg 850345P-200mg 1 x 200mg $68.00
500mg 850345P-500mg 850345P-500mg 1 x 500mg $115.00
1g 850345P-1g 850345P-1g 1 x 1g $160.00

Chloroform

Size SKU Packaging Price
25mg 850345C-25mg 850345C-25mg 1 x 25mg 10mg/mL 2.5mL $43.00
200mg 850345C-200mg 850345C-200mg 2 x 100mg 25mg/mL 4mL $68.00
500mg 850345C-500mg 850345C-500mg 1 x 500mg 25mg/mL 20mL $115.00
1g 850345C-1g 850345C-1g 2 x 500mg 25mg/mL 20mL $160.00
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14:0 PC (DMPC)

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H72NO8P
Percent Composition
C 63.78%, H 10.70%, N 2.07%, O 18.88%, P 4.57%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
18194-24-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
677.933
Exact Mass
677.500
Synonyms
<p>1,2-ditetradecanoyl-sn-glycero-3-phosphocholine</p> <p>DMPC</p> <p>PC(14:0/14:0)</p>

Kumari A, Rekhi L, Datta S. Reversibly attached phospholipid bilayer functionalized membrane pores. Langmuir. 2018 Nov 5. doi: 10.1021/acs.langmuir.8b03404. [Epub ahead of print]

PubMed ID: 30392365

Brand I, Matyszewska D, Koch KW. Binding of a Myristoylated Protein to the Lipid Membrane Influenced by Interactions with the Polar Head Group Region. Langmuir. 2018 Nov 8. doi: 10.1021/acs.langmuir.8b02265. [Epub ahead of print]

PubMed ID: 30360613

Mortensen HG, Jensen GV, Hansen SK, Vosegaard T, Pedersen JS. Structure of Phospholipid Mixed Micelles (Bicelles) Studied by Small-Angle X-ray Scattering. Langmuir. 2018 Nov 1. doi: 10.1021/acs.langmuir.8b02704. [Epub ahead of print]

PubMed ID: 30383384

Abbasi F, Alvarez-Malmagro J, Su Z, Leitch JJ, Lipkowski J. Pore Forming Properties of Alamethicin in Negatively Charged Floating Bilayer Lipid Membranes Supported on Gold Electrodes. Langmuir. 2018 Nov 1. doi: 10.1021/acs.langmuir.8b02554. [Epub ahead of print]

PubMed ID: 30265810

Frey L, Hiller S, Riek R, Bibow S. Lipid- and Cholesterol-Mediated Time-Scale-Specific Modulation of the Outer Membrane Protein X Dynamics in Lipid Bilayers. J Am Chem Soc. 2018 Oct 23. doi: 10.1021/jacs.8b09188. [Epub ahead of print]

PubMed ID: 30289706

Forest A, Ruiz M, Bouchard B, Boucher G, Gingras O, Daneault C, Robillard Frayne I, Rhainds D, Consortium TI, Genetics Consortium TNI, Tardif JC, Rioux JD, Des Rosiers C. A Comprehensive and Reproducible Untargeted Lipidomic Workflow Using LC-QTOF Validated for Human Plasma Analysis. J Proteome Res. 2018 Sep 26. doi: 10.1021/acs.jproteome.8b00270. [Epub ahead of print]

PubMed ID: 30256116

Abbasi F, Alvarez Malmagro J, Su Z, Leitch JJ, Lipkowski J. Pore forming properties of alamethicin in negatively charged floating bilayer lipid membranes supported on gold electrodes. Langmuir. 2018 Sep 28. doi: 10.1021/acs.langmuir.8b02554. [Epub ahead of print]

PubMed ID: 30265810

La Barbera G, Antonelli M, Cavaliere C, Cruciani G, Goracci L, Montone CM, Piovesana S, Laganà A, Capriotti AL. Delving into the Polar Lipidome by Optimized Chromatographic Separation, High-Resolution Mass Spectrometry, and Comprehensive Identification with Lipostar: Microalgae as Case Study. Anal Chem. 2018 Sep 24. doi: 10.1021/acs.analchem.8b03482. [Epub ahead of print]

PubMed ID: 30204416

Miranda C, Booth VK, Morrow MR. Effects of Amphipathic Polypeptides on Membrane Organization Inferred from Studies Using Bicellar Lipid Mixtures. Langmuir. 2018 Sep 20. doi: 10.1021/acs.langmuir.8b02257. [Epub ahead of print]

PubMed ID: 30196696

Harmouche N, Bechinger B. Lipid-Mediated Interactions between the Antimicrobial Peptides Magainin 2 and PGLa in Bilayers. Biophys J. 2018 Aug 16. pii: S0006-3495(18)30936-6. doi: 10.1016/j.bpj.2018.08.009. [Epub ahead of print]

PubMed ID: 30195937

Lee MT, Yang PY, Charron NE, Hsieh MH, Chang YY, Huang HW. Comparison of the Effects of Daptomycin on Bacterial and Model Membranes. Biochemistry. 2018 Sep 7. doi: 10.1021/acs.biochem.8b00818. [Epub ahead of print]

PubMed ID: 30153001

Gadbery JE, Sampson NS. Use of an Isotope-Coded Mass Tag (ICMT) Method To Determine the Orientation of Cholesterol Oxidase on Model Membranes. Biochemistry. 2018 Aug 28. doi: 10.1021/acs.biochem.8b00788. [Epub ahead of print]

PubMed ID: 30125103

Wang Q, London E. Lipid Structure and Composition Control Consequences of Interleaflet Coupling in Asymmetric Vesicles. Biophys J. 2018 Jul 19. pii: S0006-3495(18)30814-2. doi: 10.1016/j.bpj.2018.07.011. [Epub ahead of print]

PubMed ID: 30082033

Domínguez Pardo JJ, Koorengevel MC, Uwugiaren N, Weijers J, Kopf AH, Jahn H, van Walree CA, van Steenbergen MJ, Killian JA. Membrane Solubilization by Styrene-Maleic Acid Copolymers: Delineating the Role of Polymer Length. Biophys J. 2018 Jul 3;115(1):129-138. doi: 10.1016/j.bpj.2018.05.032.

PubMed ID: 29972804

Taylor GJ, Heberle FA, Seinfeld JS, Katsaras J, Collier CP , Sarles SA. Capacitive Detection of Low-Enthalpy, Higher-Order Phase Transitions in Synthetic and Natural Composition Lipid Membranes. Langmuir. 2017 Sep 26;33(38):10016-10026. doi: 10.1021/acs.langmuir.7b02022. Epub 2017 Sep 5.

PubMed ID: 28810118

Kot EF, Arseniev AS, Mineev KS. On the behavior of most widely spread lipids in isotropic bicelles. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01454. [Epub ahead of print]

PubMed ID: 29924628

Yang M, Wang K, Lin J, Wang L, Wei F, Zhu JT, Zheng W, Shen L. Gel Phase Membrane Retards Amyloid β-peptide (1-42) Fibrillation by Restricting Slaved Diffusion of Peptides on Lipid Bilayers. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01315. [Epub ahead of print]

PubMed ID: 29925241

Oropeza-Guzman E, Ruiz-Suárez JC. Dehydration/Rehydration Cycles for Mixing Phospholipids without the Use of Organic Solvent. Langmuir. 2018 May 29. doi: 10.1021/acs.langmuir.8b00799. [Epub ahead of print]

PubMed ID: 29779384

Chen Z, Moon JJ, Cheng W. Quantitation and Stability of Protein Conjugation on Liposomes for Controlled Density of Surface Epitopes. Bioconjug Chem. 2018 Mar 19. doi: 10.1021/acs.bioconjchem.8b00033.

PubMed ID: 29528624

Sarkar Y, Majumder R, Das S, Ray A, Parui PP. Detection of Curvature-Radius-Dependent Interfacial pH/Polarity for Amphiphilic Self-Assemblies: Positive versus Negative Curvature. Langmuir. 2018 May 29;34(21):6271-6284. doi: 10.1021/acs.langmuir.7b03888. Epub 2018 Jan 10.

PubMed ID: 29268016

Laursen, T., Borch, J., Knudsen, C., Torta, F., Martens, H.J., SIvestro, D., Hatzakis, N.S., Wenk, M.R., Dafforn, T.R., Olsen, C.E., Motawia, M.S., Hamberger, B., Moller, B.L., and Bassard, J-E. “Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum” Science 354, 890-893 (2016)

PubMed ID: 27856908

Phosphatidylserine Allows Observation of the Calcium–Myristoyl Switch of Recoverin and Its Preferential Binding Philippe Calvez, Thaís F. Schmidt, Line Cantin, Kristina Klinker and Christian Salesse J. Am. Chem. Soc., Article ASAP Publication Date (Web): October 11, 2016

PubMed ID: 27689444

Roy, A., R. Dutta, N. Kundu, D. Banik, and N. Sarkar. (2016). A Comparative Study of the Influence of Sugars Sucrose, Trehalose and Maltose on the Hydration and Diffusion of DMPC Lipid Bilayer at Complete Hydration: Investigation of Structural and Spectroscopic Aspect of Lipid-Sugar Interaction. Langmuir

PubMed ID: 27133799

Vamparys, L., R. Gautier, S. Vanni, W.F. Bennett, D.P. Tieleman, B. Antonny, C. Etchebest, and P.F. Fuchs. (2013). Conical Lipids in Flat Bilayers Induce Packing Defects Similar to that Induced by Positive Curvature. Biophys J 104:585-93.

PubMed ID: 23442909

Peters, G.H., C. Wang, N. Cruys-Bagger, G.F. Velardez, J.J. Madsen, and P. Westh. (2013). Binding of Serotonin to Lipid Membranes. J Am Chem Soc

PubMed ID: 23311719

Cormode DP, Chandrasekar R, Delshad A, Briley-Saebo KC, Calcagno C, Barazza A, Mulder WJ, Fisher EA, Fayad ZA. Comparison of Synthetic High Density Lipoprotein (HDL) Contrast Agents for MR Imaging of Atherosclerosis. Bioconjug Chem. 2009 Apr 20.

PubMed ID: 19378935

Probing Intermolecular Interactions in Phospholipid Bilayers by Far-Infrared Spectroscopy Giovanna D’Angelo, Valeria Conti Nibali, Cristina Crupi, Simona Rifici, Ulderico Wanderlingh, Alessandro Paciaroni, Francesco Sacchetti and Caterina Branca, J. Phys. Chem. B, Article ASAP, DOI: 10.1021/acs.jpcb.6b10323 Publication Date (Web): February 07, 2017, Copyright © 2017, American Chemical Society

PubMed ID: 28118017

Nanoroughness Strongly Impacts Lipid Mobility in Supported Membranes Florence Blachon†, Frédéric Harb‡, Bogdan Munteanu§, Agnès Piednoir†, Rémy Fulcrand†, Thierry Charitat∥, Giovanna Fragneto⊥, Olivier Pierre-Louis†, Bernard Tinland#, and Jean-Paul Rieu*† Langmuir, Article ASAP

PubMed ID: 28219008

The Influence of Metal Ions on the Dynamics of Supported Phospholipid Langmuir Films Stephen M. Baumler and Gary J. Blanchard* Langmuir, Article ASAP. DOI: 10.1021/acs.langmuir.7b00042, Publication Date (Web): March 13, 2017, Copyright © 2017, American Chemical Society

PubMed ID: 28267925

Interfacial Structure and Hydration of 3D Lipid Monolayers in Aqueous Solution, Halil I. Okur , Yixing Chen, Nikolay Smolentsev, Evangelia Zdrali, and Sylvie Roke, Phys. Chem. B, Article ASAP

PubMed ID: 28263601

Reconciling Differences between Lipid Transfer in Free-Standing and Solid Supported Membranes: A Time-Resolved Small-Angle Neutron Scattering Study Benny Wah†, Jeffrey M. Breidigan†, Joseph Adams†, Piotr Horbal†, Sumit Garg†∥, Lionel Porcar‡§, and Ursula Perez-Salas*†∥ Langmuir, Article ASAP

PubMed ID: 28300412

Ling Han, Luis C. Morales, Michele R. Richards, Elena N. Kitova, Simonetta Sipione and John S. Klassen. Investigating the Influence of Membrane Composition on Protein–Glycolipid Binding Using Nanodiscs and Proxy Ligand Electrospray Ionization Mass Spectrometry. Anal. Chem., Article ASAP

PubMed ID: 28768095

Waldie S, Lind TK, Browning K, Moulin M, Haertlein M, Forsyth VT, Luchini A, Strohmeier GA, Pichler H, Maric S, Cárdenas M. Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine. Langmuir. 2017 Dec 27. doi: 10.1021/acs.langmuir.7b02716.

PubMed ID: 29232134

Schw Ouml Rer F, Trapp M, Xu X, Soltwedel O, Dzubiella J, Steitz R, Dahint R Drastic Swelling of Lipid Oligobilayers by Polyelectrolytes - A Potential Molecular Model for the Internal Structure of Lubricating Films in Mammalian Joints. Langmuir. 2017 Dec 18. doi: 10.1021/acs.langmuir.7b03229.

PubMed ID: 29251938

Schwörer F, Trapp M, Xu X, Soltwedel O, Dzubiella J, Steitz R, Dahint R. Drastic Swelling of Lipid Oligobilayers by Polyelectrolytes: A Potential Molecular Model for the Internal Structure of Lubricating Films in Mammalian Joints. Langmuir. 2018 Jan 16. doi: 10.1021/acs.langmuir.7b03229. [Epub ahead of print]

PubMed ID: 29251938

Meher G, Chakraborty H. Influence of Eugenol on the Organization and Dynamics of Lipid Membranes: A Phase-Dependent Study. Langmuir. 2018 Jan 29. doi: 10.1021/acs.langmuir.7b03595.

PubMed ID: 29323916

Ausili A, Torrecillas A, deGodos AM, Corbalan-Garcia S, Gomez-Fernandez JC. The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes. Langmuir. 2018 Feb 15. doi: 10.1021/acs.langmuir.7b04142.

PubMed ID: ​29447442 ​

Kot EF, Goncharuk SA, Arseniev AS, Mineev KS. Phase Transitions in Small Isotropic Bicelles. Langmuir. 2018 Mar 6. doi: 10.1021/acs.langmuir.7b03610.

PubMed ID: 29486112