850345 | 14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine


Powder

Size SKU Packaging Price
25mg 850345P-25mg 850345P-25mg 1 x 25mg $46.50
200mg 850345P-200mg 850345P-200mg 1 x 200mg $74.00
500mg 850345P-500mg 850345P-500mg 1 x 500mg $125.00
1g 850345P-1g 850345P-1g 1 x 1g $170.00

Chloroform

Size SKU Packaging Price
25mg 850345C-25mg 850345C-25mg 1 x 25mg 10mg/mL 2.5mL $46.50
200mg 850345C-200mg 850345C-200mg 2 x 100mg 25mg/mL 4mL $74.00
500mg 850345C-500mg 850345C-500mg 1 x 500mg 25mg/mL 20mL $125.00
1g 850345C-1g 850345C-1g 2 x 500mg 25mg/mL 20mL $170.00
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14:0 PC (DMPC)

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H72NO8P
Percent Composition
C 63.78%, H 10.70%, N 2.07%, O 18.88%, P 4.57%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
18194-24-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
677.950
Exact Mass
677.500
Synonyms
<p>1,2-ditetradecanoyl-sn-glycero-3-phosphocholine</p>
<p>DMPC</p>
<p>PC(14:0/14:0)</p>

Buczkowski A, Gorzkiewicz M, Stepniak A, Malinowska-Michalak M, Tokarz P, Urbaniak P, Ionov M, Klajnert-Maculewicz B, Palecz B. Physicochemical and in vitro cytotoxicity studies of inclusion complex between gemcitabine and cucurbit[7]uril host. Bioorg Chem. 2020 Jun;99:103843. doi: 10.1016/j.bioorg.2020.103843. Epub 2020 Apr 13. PMID: 32305692.

PubMed ID: 32305692

Cruz N, Pinho JO, Soveral G, Ascensão L, Matela N, Reis C, Gaspar MM. A Novel Hybrid Nanosystem Integrating Cytotoxic and Magnetic Properties as a Tool to Potentiate Melanoma Therapy. Nanomaterials (Basel). 2020 Apr 6;10(4):693. doi: 10.3390/nano10040693. PMID: 32268611; PMCID: PMC7221742.

PubMed ID: 32268611

Huang P, Huang CY, Lin TC, Lin LE, Yang E, Lee C, Hsu CC, Chou PT. Toward the Rational Design of Universal Dual Polarity Matrix for MALDI Mass Spectrometry. Anal Chem. 2020 May 19;92(10):7139-7145. doi: 10.1021/acs.analchem.0c00570. Epub 2020 May 4. PMID: 32314914.

PubMed ID: 32314914

Hall SCL, Clifton LA, Tognoloni C, Morrison KA, Knowles TJ, Kinane CJ, Dafforn TR, Edler KJ, Arnold T. Adsorption of a styrene maleic acid (SMA) copolymer-stabilized phospholipid nanodisc on a solid-supported planar lipid bilayer. J Colloid Interface Sci. 2020 Apr 11;574:272-284. doi: 10.1016/j.jcis.2020.04.013. Epub ahead of print. PMID: 32330753.

PubMed ID: 32330753

Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM. A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep. 2020 Apr 28;31(4):107584. doi: 10.1016/j.celrep.2020.107584. PMID: 32348755.

PubMed ID: 32348755

He H, Liu L, Zhang S, Zheng M, Ma A, Chen Z, Pan H, Zhou H, Liang R, Cai L. Smart gold nanocages for mild heat-triggered drug release and breaking chemoresistance. J Control Release. 2020 Apr 21;323:387-397. doi: 10.1016/j.jconrel.2020.04.029. Epub ahead of print. PMID: 32330573.

PubMed ID: 32330573

Wang Y, Yuan P, Grabon A, Tripathi A, Lee D, Rodriguez M, Lönnfors M, Eisenberg-Bord M, Wang Z, Man Lam S, Schuldiner M, Bankaitis VA. Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase. J Cell Biol. 2020 May 4;219(5):e201907128. doi: 10.1083/jcb.201907128. PMID: 32303746; PMCID: PMC7199851.

PubMed ID: 32303746

Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. PMID: 32259482.

PubMed ID: 32259482

Senders ML, Meerwaldt AE, van Leent MMT, Sanchez-Gaytan BL, van de Voort JC, Toner YC, Maier A, Klein ED, Sullivan NAT, Sofias AM, Groenen H, Faries C, Oosterwijk RS, van Leeuwen EM, Fay F, Chepurko E, Reiner T, Duivenvoorden R, Zangi L, Dijkhuizen RM, Hak S, Swirski FK, Nahrendorf M, Pérez-Medina C, Teunissen AJP, Fayad ZA, Calcagno C, Strijkers GJ, Mulder WJM. Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging. Nat Nanotechnol. 2020 May;15(5):398-405. doi: 10.1038/s41565-020-0642-4. Epub 2020 Apr 20. PMID: 32313216.

PubMed ID: 32313216

Bompard J, Rosso A, Brizuela Madrid L, Mebarek S, Blum LJ, Trunfio-Sfarghiu AT, Lollo G, Granjon T, Girard-Egrot A, Maniti O. Membrane Fluidity as a New Mean to Selectively Target Cancer Cells with Fusogenic Lipid Carriers. Langmuir. 2020 Apr 27. doi: 10.1021/acs.langmuir.0c00262. Epub ahead of print. PMID: 32338922.

PubMed ID: 32338922

Golubev A, Fatkhullin B, Gabdulkhakov A, Bikmullin A, Nurullina L, Garaeva N, Islamov D, Klochkova E, Klochkov V, Aganov A, Khusainov I, Validov S, Yusupova G, Yusupov M, Usachev K. NMR and crystallographic structural studies of the Elongation factor P from Staphylococcus aureus. Eur Biophys J. 2020 Mar 9. doi: 10.1007/s00249-020-01428-x. Epub ahead of print. PMID: 32152681.

PubMed ID: 32152681

Kim D, Han J, Park SY, Kim H, Park JH, Lee HJ. Antitumor Efficacy of Focused Ultrasound-MFL Nanoparticles Combination Therapy in Mouse Breast Cancer Xenografts. Materials (Basel). 2020 Mar 2;13(5):1099. doi: 10.3390/ma13051099. PMID: 32121631; PMCID: PMC7084991.

PubMed ID: 32121631

Gaddi GM, Gisonno RA, Rosú SA, Curto LM, Prieto ED, Schinella GR, Finarelli GS, Cortez MF, Bauzá L, Elías EE, Ramella NA, Tricerri MA. Structural analysis of a natural apolipoprotein A-I variant (L60R) associated with amyloidosis. Arch Biochem Biophys. 2020 May 30;685:108347. doi: 10.1016/j.abb.2020.108347. Epub 2020 Mar 16. PMID: 32194045.

PubMed ID: 32194045

Lubart Q , Hannestad JK , Pace H , Fjällborg D , Westerlund F , Esbjörner EK , Bally M . Lipid vesicle composition influences the incorporation and fluorescence properties of the lipophilic sulphonated carbocyanine dye SP-DiO. Phys Chem Chem Phys. 2020 Apr 28;22(16):8781-8790. doi: 10.1039/c9cp04158c. Epub 2020 Apr 14. PMID: 32285050.

PubMed ID: 32285050

Pham QD, Carlström G, Lafon O, Sparr E, Topgaard D. Quantification of the amount of mobile components in intact stratum corneum with natural-abundance 13C solid-state NMR. Phys Chem Chem Phys. 2020 Mar 25;22(12):6572-6583. doi: 10.1039/d0cp00079e. PMID: 32159206.

PubMed ID: 32159206

Beriashvili D, Spencer NR, Dieckmann T, Overduin M, Palmer M. Characterization of multimeric daptomycin bound to lipid nanodiscs formed by calcium-tolerant styrene-maleic acid copolymer. Biochim Biophys Acta Biomembr. 2020 Jun 1;1862(6):183234. doi: 10.1016/j.bbamem.2020.183234. Epub 2020 Mar 5. PMID: 32145282.

PubMed ID: 32145282

Flinois T, Lebègue E, Zebda A, Alcaraz JP, Martin DK, Barrière F. Assisted lipid deposition by reductive electrochemical aryldiazonium grafting and insertion of the antiport NhaA protein in this stable biomimetic membrane. Colloids Surf B Biointerfaces. 2020 Mar 2;190:110924. doi: 10.1016/j.colsurfb.2020.110924. Epub ahead of print. PMID: 32146278.

PubMed ID: 32146278

Saem S, Shahid O, Khondker A, Moran-Hidalgo C, Rheinstädter MC, Moran-Mirabal J. Benchtop-fabricated lipid-based electrochemical sensing platform for the detection of membrane disrupting agents. Sci Rep. 2020 Mar 12;10(1):4595. doi: 10.1038/s41598-020-61561-7. PMID: 32165701; PMCID: PMC7067837.

PubMed ID: 32165701

Alvarez-Malmagro J, Jablonowska E, Nazaruk E, Szwedziak P, Bilewicz R. How do lipid nanocarriers - Cubosomes affect electrochemical properties of DMPC bilayers deposited on gold (111) electrodes? Bioelectrochemistry. 2020 Mar 20;134:107516. doi: 10.1016/j.bioelechem.2020.107516. Epub ahead of print. PMID: 32222670.

PubMed ID: 32222670

Gu J, Chen Y, Tong L, Wang X, Yu D, Wu H. Astaxanthin-loaded polymer-lipid hybrid nanoparticles (ATX-LPN): assessment of potential otoprotective effects. J Nanobiotechnology. 2020 Mar 19;18(1):53. doi: 10.1186/s12951-020-00600-x. PMID: 32192504; PMCID: PMC7081530.

PubMed ID: 32192504

Maciel E, Domingues P, Domingues MRM, Calado R, Lillebø A. Halophyte plants from sustainable marine aquaponics are a valuable source of omega-3 polar lipids. Food Chem. 2020 Aug 1;320:126560. doi: 10.1016/j.foodchem.2020.126560. Epub 2020 Mar 6. PMID: 32203828.

PubMed ID: 32203828

Fritzen AM, Domingo-Espín J, Lundsgaard AM, Kleinert M, Israelsen I, Carl CS, Nicolaisen TS, Kjøbsted R, Jeppesen JF, Wojtaszewski JFP, Lagerstedt JO, Kiens B. ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2. Mol Metab. 2020 Mar 4;35:100949. doi: 10.1016/j.molmet.2020.01.013. Epub ahead of print. PMID: 32244181; PMCID: PMC7082546.

PubMed ID: 32244181

Weston M, Kuchel RP, Ciftci M, Boyer C, Chandrawati R. A polydiacetylene-based colorimetric sensor as an active use-by date indicator for milk. J Colloid Interface Sci. 2020 Mar 18;572:31-38. doi: 10.1016/j.jcis.2020.03.040. Epub ahead of print. PMID: 32224349.

PubMed ID: 32224349

Santa-Marinha L, Castanho I, Silva RR, Bravo FV, Miranda AM, Meira T, Morais-Ribeiro R, Marques F, Xu Y, Point du Jour K, Wenk M, Chan RB, Di Paolo G, Pinto V, Oliveira TG. Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning. Cell Rep. 2020 Mar 24;30(12):4197-4208.e6. doi: 10.1016/j.celrep.2020.02.102. PMID: 32209478.

PubMed ID: 32209478

Lu L, Qi S, Chen Y, Luo H, Huang S, Yu X, Luo Q, Zhang Z. Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis. Biomaterials. 2020 Jul;245:119987. doi: 10.1016/j.biomaterials.2020.119987. Epub 2020 Mar 19. PMID: 32229332.

PubMed ID: 32229332

Yu X, Dai Y, Zhao Y, Qi S, Liu L, Lu L, Luo Q, Zhang Z. Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response. Nat Commun. 2020 Feb 28;11(1):1110. doi: 10.1038/s41467-020-14906-9. PMID: 32111828; PMCID: PMC7048802.

PubMed ID: 32111828

Bryce DA, Kitt JP, Myres GJ, Harris JM. Confocal Raman Microscopy Investigation of Phospholipid Monolayers Deposited on Nitrile-Modified Surfaces in Porous Silica Particles. Langmuir. 2020 Apr 7. doi: 10.1021/acs.langmuir.0c00456. Epub ahead of print. PMID: 32212663.

PubMed ID: 32212663

Bolmatov D, Soloviov D, Zhernenkov M, Zav'yalov D, Mamontov E, Suvorov A, Cai YQ, Katsaras J. A Molecular Picture of The Transient Nature of Lipid Rafts. Langmuir. 2020 Apr 7. doi: 10.1021/acs.langmuir.0c00125. Epub ahead of print. PMID: 32259453.

PubMed ID: 32259453

Rieth MD, Root KT, Glover KJ. Reconstitution of full-length human caveolin-1 into phospholipid bicelles: Validation by analytical ultracentrifugation. Biophys Chem. 2020 Apr;259:106339. doi: 10.1016/j.bpc.2020.106339. Epub 2020 Feb 26. PMID: 32145579.

PubMed ID: 32145579

Quan LM, Mechler AI, Barnard PJ. A luminescent lipid mimetic iridium(III) N-heterocyclic carbene complex for membrane labelling. J Inorg Biochem. 2020 May;206:111047. doi: 10.1016/j.jinorgbio.2020.111047. Epub 2020 Feb 21. PMID: 32151874.

PubMed ID: 32151874

Latza VM, Demé B, Schneck E. Membrane Adhesion via Glycolipids Occurs for Abundant Saccharide Chemistries. Biophys J. 2020 Feb 12:S0006-3495(20)30122-3. doi: 10.1016/j.bpj.2020.02.003. Epub ahead of print. PMID: 32097623.

PubMed ID: 32097623

Pérez HA, Cejas JP, Rosa AS, Giménez RE, Disalvo EA, Frías MA. Modulation of Interfacial Hydration by Carbonyl Groups in Lipid Membranes. Langmuir. 2020 Mar 17;36(10):2644-2653. doi: 10.1021/acs.langmuir.9b03551. Epub 2020 Mar 2. PMID: 32073276.

PubMed ID: 32073276

Azouz M, Gonin M, Fiedler S, Faherty J, Decossas M, Cullin C, Villette S, Lafleur M, D Alves I, Lecomte S, Ciaccafava A. Microfluidic diffusional sizing probes lipid nanodiscs formation. Biochim Biophys Acta Biomembr. 2020 Feb 20;1862(6):183215. doi: 10.1016/j.bbamem.2020.183215. Epub ahead of print. PMID: 32061645.

PubMed ID: 32061645

Suga K, Kitagawa K, Taguchi S, Okamoto Y, Umakoshi H. Evaluation of Molecular Ordering in Bicelle Bilayer Membranes Based on Induced Circular Dichroism Spectra. Langmuir. 2020 Mar 20. doi: 10.1021/acs.langmuir.9b03710. Epub ahead of print. PMID: 32163713.

PubMed ID: 32163713

Drabik D, Chodaczek G, Kraszewski S, Langner M. Mechanical Properties Determination of DMPC, DPPC, DSPC, and HSPC Solid-Ordered Bilayers. Langmuir. 2020 Mar 24. doi: 10.1021/acs.langmuir.0c00475. Epub ahead of print. PMID: 32176506.

PubMed ID: 32176506

Yeh V, Goode A, Eastham G, Rambo R, Inoue K, Doutch JJ, Bonev BB. Membrane stability in the presence of methacrylate esters. Langmuir. 2020 Mar 23. doi: 10.1021/acs.langmuir.9b03759. Epub ahead of print. PMID: 32202793.

PubMed ID: 32202793

Drabik D, Chodaczek G, Kraszewski S, Langner M. Mechanical properties determination of DMPC, DPPC, DSPC and HSPC solid-ordered bilayers. Langmuir. 2020 Mar 16. doi: 10.1021/acs.langmuir.0c00475. Epub ahead of print. PMID: 32176506.

PubMed ID: 32176506

Pérez HA, Cejas JP, Rosa AS, Giménez RE, Disalvo EA, Frías MA. Modulation of Interfacial Hydration by Carbonyl Groups in Lipid Membranes. Langmuir. 2020 Mar 17;36(10):2644-2653. doi: 10.1021/acs.langmuir.9b03551. Epub 2020 Mar 2. PMID: 32073276.

PubMed ID: 32073276

Suga K, Kitagawa K, Taguchi S, Okamoto Y, Umakoshi H. Evaluation of Molecular Ordering in Bicelle Bilayer Membranes Based on Induced Circular Dichroism Spectra. Langmuir. 2020 Mar 12. doi: 10.1021/acs.langmuir.9b03710. Epub ahead of print. PMID: 32163713.

PubMed ID: 32163713

Robertson IM, Klein BA, Sykes BD. Optimizing fluorine labelling for 19F solid-state NMR in oriented biological systems. J Biomol NMR. 2020 Jan;74(1):1-7. doi: 10.1007/s10858-019-00296-8. Epub 2020 Jan 7. PMID: 31912345.

PubMed ID: 31912345

Momtazi-Borojeni AA, Nik ME, Jaafari MR, Banach M, Sahebkar A. Effects of immunisation against PCSK9 in mice bearing melanoma. Arch Med Sci. 2019 Dec 31;16(1):189-199. doi: 10.5114/aoms.2020.91291. PMID: 32051723; PMCID: PMC6963136.

PubMed ID: 32051723

Brubaker G, Lorkowski SW, Gulshan K, Hazen SL, Gogonea V, Smith JD. First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation. PLoS One. 2020 Jan 16;15(1):e0221915. doi: 10.1371/journal.pone.0221915. PMID: 31945064; PMCID: PMC6964839.

PubMed ID: 31945064

Sarkar Y , Roy S , Majumder R , Das S , Bhalani DV , Ray A , Jewrajka SK , Parui PP . Protonation-induced pH increase at the triblock copolymer micelle interface for transient membrane permeability at neutral pH. Soft Matter. 2020 Jan 22;16(3):798-809. doi: 10.1039/c9sm01002e. PMID: 31834342.

PubMed ID: 31834342

Yu J, Mao J, Nagao M, Bu W, Lin B, Hong K, Jiang Z, Liu Y, Qian S, Tirrell M, Chen W. Structure and dynamics of lipid membranes interacting with antivirulence end-phosphorylated polyethylene glycol block copolymers. Soft Matter. 2020 Jan 28;16(4):983-989. doi: 10.1039/c9sm01642b. Epub 2019 Dec 18. PMID: 31851201.

PubMed ID: 31851201

Kanwa N, De SK, Maity A, Chakraborty A. Interaction of aliphatic amino acids with zwitterionic and charged lipid membranes: hydration and dehydration phenomena. Phys Chem Chem Phys. 2020 Feb 14;22(6):3234-3244. doi: 10.1039/c9cp06188f. Epub 2020 Jan 29. PMID: 31994545.

PubMed ID: 31994545

Matsuki H, Goto M, Motohashi M, Kiguchi A, Nakao T, Tamai N. Formation of intermediate gel-liquid crystalline phase on medium-chain phosphatidylcholine bilayers: Phase transitions depending on the bilayer packing. Biochim Biophys Acta Biomembr. 2020 Jan 17;1862(5):183197. doi: 10.1016/j.bbamem.2020.183197. Epub ahead of print. PMID: 31958435.

PubMed ID: 31958435

Karanth S, Delcea M. Nitrosative stress affects the interaction of integrin alphaIIbbeta3 with its ligands. Biochim Biophys Acta Biomembr. 2020 Jan 17:183198. doi: 10.1016/j.bbamem.2020.183198. Epub ahead of print. PMID: 31958436.

PubMed ID: 31958436

Schmidt ML, Davis JH. 2 H NMR of oriented phospholipid/cholesterol bilayers containing an amphiphilic peptide. Biochim Biophys Acta Biomembr. 2020 Jan 18;1862(5):183196. doi: 10.1016/j.bbamem.2020.183196. Epub ahead of print. PMID: 31958437.

PubMed ID: 31958437

Okotrub KA , Zykova VA , Adichtchev SV , Surovtsev NV . Deciphering the orientation of lipid molecules by principal component analysis of Raman mapping data. Analyst. 2020 Feb 17;145(4):1466-1472. doi: 10.1039/c9an01499c. PMID: 31868187.

PubMed ID: 31868187

Wong P, Li L, Chea J, Hu W, Poku E, Ebner T, Bowles N, Wong JYC, Yazaki PJ, Sligar S, Shively JE. Antibody Targeted PET Imaging of 64Cu-DOTA-Anti-CEA PEGylated Lipid Nanodiscs in CEA Positive Tumors. Bioconjug Chem. 2020 Jan 30:10.1021/acs.bioconjchem.9b00854. doi: 10.1021/acs.bioconjchem.9b00854. Epub ahead of print. PMID: 31961138.

PubMed ID: 31961138

Peterka O, Jirásko R, Chocholoušková M, Kuchař L, Wolrab D, Hájek R, Vrána D, Strouhal O, Melichar B, Holčapek M. Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jan 21;1865(5):158634. doi: 10.1016/j.bbalip.2020.158634. Epub ahead of print. PMID: 31978556.

PubMed ID: 31978556

Kim HY, Cheon JH, Lee SH, Min JY, Back SY, Song JG, Kim DH, Lim SJ, Han HK. Ternary nanocomposite carriers based on organic clay-lipid vesicles as an effective colon-targeted drug delivery system: preparation and in vitro/in vivo characterization. J Nanobiotechnology. 2020 Jan 21;18(1):17. doi: 10.1186/s12951-020-0579-7. PMID: 31964393; PMCID: PMC6975051.

PubMed ID: 31964393

He W, Evans AC, Rasley A, Bourguet F, Peters S, Kamrud KI, Wang N, Hubby B, Felderman M, Gouvis H, Coleman MA, Fischer NO. Cationic HDL mimetics enhance in vivo delivery of self-replicating mRNA. Nanomedicine. 2020 Jan 24;24:102154. doi: 10.1016/j.nano.2020.102154. Epub ahead of print. PMID: 31982617.

PubMed ID: 31982617

Lebègue E, Barrière F, Bard AJ. Lipid Membrane Permeability of Synthetic Redox DMPC Liposomes Investigated by Single Electrochemical Collisions. Anal Chem. 2020 Feb 4;92(3):2401-2408. doi: 10.1021/acs.analchem.9b02809. Epub 2020 Jan 21. PMID: 31916438.

PubMed ID: 31916438

Han L, Kitov PI, Li J, Kitova EN, Klassen JS. Probing Heteromultivalent Protein-Glycosphingolipid Interactions using Native Mass Spectrometry and Nanodiscs. Anal Chem. 2020 Feb 12:10.1021/acs.analchem.9b05419. doi: 10.1021/acs.analchem.9b05419. Epub ahead of print. PMID: 31944669.

PubMed ID: 31944669

Zhou S, Huang Y, Chen Y, Liu S, Xu M, Jiang T, Song Q, Jiang G, Gu X, Gao X, Chen J. Engineering ApoE3-incorporated biomimetic nanoparticle for efficient vaccine delivery to dendritic cells via macropinocytosis to enhance cancer immunotherapy. Biomaterials. 2020 Mar;235:119795. doi: 10.1016/j.biomaterials.2020.119795. Epub 2020 Jan 16. PMID: 32014739.

PubMed ID: 32014739

Ahn SI, Sei YJ, Park HJ, Kim J, Ryu Y, Choi JJ, Sung HJ, MacDonald TJ, Levey AI, Kim Y. Microengineered human blood-brain barrier platform for understanding nanoparticle transport mechanisms. Nat Commun. 2020 Jan 10;11(1):175. doi: 10.1038/s41467-019-13896-7. PMID: 31924752; PMCID: PMC6954233.

PubMed ID: 31924752

Li Q, Li S, Zhang X, Xu W, Han X. Programmed magnetic manipulation of vesicles into spatially coded prototissue architectures arrays. Nat Commun. 2020 Jan 13;11(1):232. doi: 10.1038/s41467-019-14141-x. PMID: 31932592; PMCID: PMC6957477.

PubMed ID: 31932592

Jiang T, Hall A, Eres M, Hemmatian Z, Qiao B, Zhou Y, Ruan Z, Couse AD, Heller WT, Huang H, de la Cruz MO, Rolandi M, Xu T. Single-chain heteropolymers transport protons selectively and rapidly. Nature. 2020 Jan;577(7789):216-220. doi: 10.1038/s41586-019-1881-0. Epub 2020 Jan 8. PMID: 31915399.

PubMed ID: 31915399

Okabe M, Taga K, Yoshino A, Yamamoto Y, Taneda A, Shinoda S, Kanamasa S, Shervani Z. Effect of Escherichia coli on phospholipid monolayers: surface tensiometry and Brewster angle microscopy measurements. Eur Biophys J. 2020 Jan;49(1):71-84. doi: 10.1007/s00249-019-01413-z. Epub 2019 Dec 20. PMID: 31863194.

PubMed ID: 31863194

Lone A, Thomsen TT, Nielsen JE, Thulstrup PW, Klitgaard RN, Løbner-Olesen A, Lund R, Jenssen H, Hansen PR. Structure-Activity Study of an All-d Antimicrobial Octapeptide D2D. Molecules. 2019 Dec 13;24(24):4571. doi: 10.3390/molecules24244571. PMID: 31847173; PMCID: PMC6943423.

PubMed ID: 31847173

Asamoto DK, Kang G, Kim JE. Folding of the β-Barrel Membrane Protein OmpA into Nanodiscs. Biophys J. 2020 Jan 21;118(2):403-414. doi: 10.1016/j.bpj.2019.11.3381. Epub 2019 Nov 28. PMID: 31843264; PMCID: PMC6976806.

PubMed ID: 31843264

Staton JA, Stearns SW, Dungan SR. Mechanism of Time-Dependent Adsorption for Phosphatidylcholine onto a Clean Air-Water Interface from a Dispersion of Vesicles: Effect of Temperature and Acyl Chain Length. Langmuir. 2019 Dec 24;35(51):16850-16861. doi: 10.1021/acs.langmuir.9b02904. Epub 2019 Dec 9. PMID: 31815494.

PubMed ID: 31815494

Lubbers R, Oostindie SC, Dijkstra DJ, Parren PWHI, Verheul MK, Abendstein L, Sharp TH, de Ru A, Janssen GMC, van Veelen PA, van den Bremer ETJ, Bleijlevens B, de Kreuk BJ, Beurskens FJ, Trouw LA. Carbamylation reduces the capacity of IgG for hexamerization and complement activation. Clin Exp Immunol. 2019 Dec 19;10.1111/cei.13411. doi: 10.1111/cei.13411. [Epub ahead of print]. PMID: 31853959.

PubMed ID: 31853959

Mias-Lucquin D, Dos Santos Morais R, Chéron A, Lagarrigue M, Winder SJ, Chenuel T, Pérez J, Appavou MS, Martel A, Alviset G, Le Rumeur E, Combet S, Hubert JF, Delalande O. How the central domain of dystrophin acts to bridge F-actin to sarcolemmal lipids. J Struct Biol. 2020 Jan 1;209(1):107411. doi: 10.1016/j.jsb.2019.107411. Epub 2019 Nov 2. PMID: 31689503.

PubMed ID: 31689503

Konstantinidi A, Chountoulesi M, Naziris N, Sartori B, Amenitsch H, Mali G, Čendak T, Plakantonaki M, Triantafyllakou I, Tselios T, Demetzos C, Busath DD, Mavromoustakos T, Kolocouris A. The boundary lipid around DMPC-spanning influenza A M2 transmembrane domain channels: Its structure and potential for drug accommodation. Biochim Biophys Acta Biomembr. 2020 Mar 1;1862(3):183156. doi: 10.1016/j.bbamem.2019.183156. Epub 2019 Dec 14. PMID: 31846647.

PubMed ID: 31846647

Sou K, Chan LY, Arai S, Lee CK. Highly cooperative fluorescence switching of self-assembled squaraine dye at tunable threshold temperatures using thermosensitive nanovesicles for optical sensing and imaging. Sci Rep. 2019 Nov 29;9(1):17991. doi: 10.1038/s41598-019-54418-1. PMID: 31784685; PMCID: PMC6884458.

PubMed ID: 31784685

Hussain MT, Forbes N, Perrie Y, Malik KP, Duru C, Matejtschuk P. Freeze-drying cycle optimization for the rapid preservation of protein-loaded liposomal formulations. Int J Pharm. 2020 Jan 5;573:118722. doi: 10.1016/j.ijpharm.2019.118722. Epub 2019 Nov 6. PMID: 31705976.

PubMed ID: 31705976

Verma A, Schmidt BA, Elizaldi SR, Nguyen NK, Walter KA, Beck Z, Trinh HV, Dinsarapu AR, Lakshmanappa YS, Rane NN, Matyas GR, Rao M, Shen X, Tomaras GD, LaBranche CC, Reimann KA, Foehl DH, Gach JS, Forthal DN, Kozlowski PA, Amara RR, Iyer SS. Impact of Th1 CD4 TFH skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. J Virol. 2019 Dec 11;JVI.01737-19. doi: 10.1128/JVI.01737-19. [Epub ahead of print]. PMID: 31827000.

PubMed ID: 31827000

Konopko A, Kusio J, Litwinienko G. Antioxidant Activity of Metal Nanoparticles Coated with Tocopherol-Like Residues-The Importance of Studies in Homo- and Heterogeneous Systems. Antioxidants (Basel). 2019 Dec 19;9(1):E5. doi: 10.3390/antiox9010005. PMID: 31861581.

PubMed ID: 31861581

Li H, Song Y, Zhang H, Wang X, Cong P, Xu J, Xue C. Comparative lipid profile of four edible shellfishes by UPLC-Triple TOF-MS/MS. Food Chem. 2020 Apr 25;310:125947. doi: 10.1016/j.foodchem.2019.125947. Epub 2019 Dec 4. PMID: 31841939.

PubMed ID: 31841939

Nordström R, Browning KL, Parra-Ortiz E, Damgaard LSE, Häffner SM, Maestro A, Campbell RA, Cooper JFK, Malmsten M. Membrane interactions of antimicrobial peptide-loaded microgels. J Colloid Interface Sci. 2020 Mar 7;562:322-332. doi: 10.1016/j.jcis.2019.12.022. Epub 2019 Dec 9. PMID: 31855795.

PubMed ID: 31855795

Momtazi-Borojeni AA, Jaafari MR, Badiee A, Banach M, Sahebkar A. Therapeutic effect of nanoliposomal PCSK9 vaccine in a mouse model of atherosclerosis. BMC Med. 2019;17(1):223. Published 2019 Dec 10. doi:10.1186/s12916-019-1457-8

PubMed ID: 31818299

Pinheiro M, Amenitsch H, Reis S. Antituberculosis Drug Interactions with Membranes: A Biophysical Approach Applied to Bedaquiline. Membranes (Basel). 2019 Oct 30;9(11). pii: E141. doi: 10.3390/membranes9110141.

PubMed ID: 31671599

Shi D, Nguyen DV, Maaloum M, Gallani JL, Felder-Flesch D, Krafft MP. Interfacial Behavior of Oligo(Ethylene Glycol) Dendrons Spread Alone and in Combination with a Phospholipid as Langmuir Monolayers at the Air/Water Interface. Molecules. 2019 Nov 14;24(22). pii: E4114. doi: 10.3390/molecules24224114.

PubMed ID: 31739495

Pérez-Isidoro R, Ruiz-Suárez JC. Thermal behavior of a lipid-protein membrane model and the effects produced by anesthetics and neurotransmitters. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183099. doi: 10.1016/j.bbamem.2019.183099. Epub 2019 Nov 4.

PubMed ID: 31697903

Sustich SJ, Afrose F, Greathouse DV, Koeppe RE 2nd. Influence of interfacial tryptophan residues on an arginine-flanked transmembrane helix. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183134. doi: 10.1016/j.bbamem.2019.183134. Epub 2019 Nov 16.

PubMed ID: 31738898

Perczyk P, Wójcik A, Wydro P, Broniatowski M. The role of phospholipid composition and ergosterol presence in the adaptation of fungal membranes to harsh environmental conditions-membrane modeling study. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183136. doi: 10.1016/j.bbamem.2019.183136. Epub 2019 Nov 18.

PubMed ID: 31751523

Mücksch F, Citir M, Lüchtenborg C, Glass B, Traynor-Kaplan A, Schultz C, Brügger B, Kräusslich HG. Quantification of phosphoinositides reveals strong enrichment of PIP2 in HIV-1 compared to producer cell membranes. Sci Rep. 2019 Nov 27;9(1):17661. doi: 10.1038/s41598-019-53939-z.

PubMed ID: 31776383

Muhanna N, Chan H, Townson JL, Jin CS, Ding L, Valic M, Douglas CM, Maclaughlin CM, Chen J, Zheng G, Irish JC. Photodynamic therapy enables tumor specific ablation in preclinical models of thyroid cancer. Endocr Relat Cancer. 2019 Nov 1. pii: ERC-19-0258.R2. doi: 10.1530/ERC-19-0258. [Epub ahead of print]

PubMed ID: 31751308

Bratanov D, Kovalev K, Machtens JP, Astashkin R, Chizhov I, Soloviov D, Volkov D, Polovinkin V, Zabelskii D, Mager T, Gushchin I, Rokitskaya T, Antonenko Y, Alekseev A, Shevchenko V, Yutin N, Rosselli R, Baeken C, Borshchevskiy V, Bourenkov G, Popov A, Balandin T, Büldt G, Manstein DJ, Rodriguez-Valera F, Fahlke C, Bamberg E, Koonin E, Gordeliy V. Unique structure and function of viral rhodopsins. Nat Commun. 2019 Oct 30;10(1):4939. doi: 10.1038/s41467-019-12718-0.

PubMed ID: 3166521

Handumrongkul C, Ye AL, Chmura SA, Soroceanu L, Mack M, Ice RJ, Thistle R, Myers M, Ursu SJ, Liu Y, Kashani-Sabet M, Heath TD, Liggitt D, Lewis DB, Debs R. Durable multitransgene expression in vivo using systemic, nonviral DNA delivery. Sci Adv. 2019 Nov 27;5(11):eaax0217. doi: 10.1126/sciadv.aax0217. eCollection 2019 Nov.

PubMed ID: 31807699

Pinto P, Machado CM, Moreira J, Almeida JDP, Silva PMA, Henriques AC, Soares JX, Salvador JAR, Afonso C, Pinto M, Bousbaa H, Cidade H. Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity. Eur J Med Chem. 2019 Dec 15;184:111752. doi: 10.1016/j.ejmech.2019.111752. Epub 2019 Oct 3.

PubMed ID: 31610374

Mirtaheri E, Dolatmoradi A, El-Zahab B. Thermally Assisted Acoustofluidic Separation Based on Membrane Protein Content. Anal Chem. 2019 Nov 5;91(21):13953-13961. doi: 10.1021/acs.analchem.9b03485. Epub 2019 Oct 25.

PubMed ID: 31590489

Leninger M, Sae Her A, Traaseth NJ. Inducing conformational preference of the membrane protein transporter EmrE through conservative mutations. Elife. 2019 Oct 22;8. pii: e48909. doi: 10.7554/eLife.48909.

PubMed ID: 31637997

Kapsalis C, Wang B, El Mkami H, Pitt SJ, Schnell JR, Smith TK, Lippiat JD, Bode BE, Pliotas C. Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets. Nat Commun. 2019 Oct 10;10(1):4619. doi: 10.1038/s41467-019-12591-x.

PubMed ID: 31601809

Nirod Kumar Sarangi and Jaydeep Kumar Basu. Preferential binding and re-organization of nanoscale domains on model lipid membranes by pore-forming toxins: insight from STED-FCS. Journal of Physics D: Applied Physics, Volume 52, Number 50.


McKay MJ, Fu R, Greathouse DV, Koeppe RE. Breaking the Backbone: Central Arginine Residues Induce Membrane Exit and Helix Distortions within a Dynamic Membrane Peptide. J Phys Chem B. 2019 Sep 26;123(38):8034-8047. doi: 10.1021/acs.jpcb.9b06034. Epub 2019 Sep 17.

PubMed ID: 31483653

Lopes D, Melo T, Meneses J, Abreu MH, Pereira R, Domingues P, Lillebø AI, Calado R, Domingues MR. A New Look for the Red Macroalga Palmaria palmata: A Seafood with Polar Lipids Rich in EPA and with Antioxidant Properties. Mar Drugs. 2019 Sep 13;17(9). pii: E533. doi: 10.3390/md17090533.

PubMed ID: 31540326

Wójcik P, Biernacki M, Wroński A, Łuczaj W, Waeg G, Žarković N, Skrzydlewska E. Altered Lipid Metabolism in Blood Mononuclear Cells of Psoriatic Patients Indicates Differential Changes in Psoriasis Vulgaris and Psoriatic Arthritis. Int J Mol Sci. 2019 Aug 30;20(17). pii: E4249. doi: 10.3390/ijms20174249.

PubMed ID: 31480263

Pedersbæk D, Kræmer MK, Kempen PJ, Ashley J, Braesch-Andersen S, Andresen TL, Simonsen JB. The Composition of Reconstituted High-Density Lipoproteins (rHDL) Dictates the Degree of rHDL Cargo- and Size-Remodeling via Direct Interactions with Endogenous Lipoproteins. Bioconjug Chem. 2019 Oct 16;30(10):2634-2646. doi: 10.1021/acs.bioconjchem.9b00552. Epub 2019 Sep 19.

PubMed ID: 31487985

Smriti Sultana, Binte Mustafiz, Toru Uyama, Katsuya Morito, Naoko Takahashi, Katsuhisa Kawai, Zahir Hussain, Kazuhito Tsuboi, Nobukazu Araki, Kei Yamamoto, Tamotsu Tanaka, Natsuo Ueda. Intracellular Ca2+-dependent formation of N-acyl-phosphatidylethanolamines by human cytosolic phospholipase A2ε. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2019 December;1864:12,158515. doi: 10.1016/j.bbalip.2019.158515


Schwartz AC, Jay DW, Parnham S, Giuliano MW. Sequential and Environmental Dependence of Conformation in a Small Opioid Peptide. J Org Chem. 2019 Oct 15. doi: 10.1021/acs.joc.9b01141. [Epub ahead of print]

PubMed ID: 31538782

Zinger A, Koren L, Adir O, Poley M, Alyan M, Yaari Z, Noor N, Krinsky N, Simon A, Gibori H, Krayem M, Mumblat Y, Kasten S, Ofir S, Fridman E, Milman N, Lübtow MM, Liba L, Shklover J, Shainsky-Roitman J, Binenbaum Y, Hershkovitz D, Gil Z, Dvir T, Luxenhofer R, Satchi-Fainaro R, Schroeder A. Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors. ACS Nano. 2019 Sep 20. doi: 10.1021/acsnano.9b02395. [Epub ahead of print]

PubMed ID: 31503443

Tasso TT, Schlothauer JC, Junqueira HC, Matias TA, Araki K, Liandra-Salvador É, Antonio FCT, Homem-de-Mello P, Baptista MS. Photobleaching Efficiency Parallels the Enhancement of Membrane Damage for Porphyrazine Photosensitizers. J Am Chem Soc. 2019 Oct 2;141(39):15547-15556. doi: 10.1021/jacs.9b05991. Epub 2019 Sep 18.

PubMed ID: 31490678

Eddy MT, Yu TY, Wagner G, Griffin RG. Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR. J Biomol NMR. 2019 Aug 12. doi: 10.1007/s10858-019-00242-8. [Epub ahead of print]

PubMed ID: 31407201

Bose D, Chakrabarti A. Chaperone potential of erythroid spectrin: Effects of hemoglobin interaction, macromolecular crowders, phosphorylation and glycation. Biochim Biophys Acta Proteins Proteom. 2019 Nov;1867(11):140267. doi: 10.1016/j.bbapap.2019.140267. Epub 2019 Aug 27.

PubMed ID: 31470132

Dushianthan A, Cusack R, Koster G, Grocott MPW, Postle AD. Insight into erythrocyte phospholipid molecular flux in healthy humans and in patients with acute respiratory distress syndrome. PLoS One. 2019 Aug 27;14(8):e0221595. doi: 10.1371/journal.pone.0221595. eCollection 2019.

PubMed ID: 31454387

Szymkowicz L, Lento C, Wilson DJ. Impact of Cardiolipin and Phosphatidylcholine Interactions on the Conformational Ensemble of Cytochrome c. Biochemistry. 2019 Aug 27;58(34):3617-3626. doi: 10.1021/acs.biochem.9b00495. Epub 2019 Aug 12.

PubMed ID: 31380624

Sharma VK, Nagao M, Rai DK, Mamontov E. Membrane softening by nonsteroidal anti-inflammatory drugs investigated by neutron spin echo. Phys Chem Chem Phys. 2019 Sep 18;21(36):20211-20218. doi: 10.1039/c9cp03767e.

PubMed ID: 31486459

Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol