850345 | 14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine


Powder

Size SKU Packaging Price
25mg 850345P-25mg 850345P-25mg 1 x 25mg $46.50
200mg 850345P-200mg 850345P-200mg 1 x 200mg $74.00
500mg 850345P-500mg 850345P-500mg 1 x 500mg $125.00
1g 850345P-1g 850345P-1g 1 x 1g $170.00

Chloroform

Size SKU Packaging Price
25mg 850345C-25mg 850345C-25mg 1 x 25mg 10mg/mL 2.5mL $46.50
200mg 850345C-200mg 850345C-200mg 2 x 100mg 25mg/mL 4mL $74.00
500mg 850345C-500mg 850345C-500mg 1 x 500mg 25mg/mL 20mL $125.00
1g 850345C-1g 850345C-1g 2 x 500mg 25mg/mL 20mL $170.00
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14:0 PC (DMPC)

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H72NO8P
Percent Composition
C 63.78%, H 10.70%, N 2.07%, O 18.88%, P 4.57%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
18194-24-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
677.950
Exact Mass
677.500
Synonyms
<p>1,2-ditetradecanoyl-sn-glycero-3-phosphocholine</p> <p>DMPC</p> <p>PC(14:0/14:0)</p>

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PubMed ID: 31945064

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Matsuki H, Goto M, Motohashi M, Kiguchi A, Nakao T, Tamai N. Formation of intermediate gel-liquid crystalline phase on medium-chain phosphatidylcholine bilayers: Phase transitions depending on the bilayer packing. Biochim Biophys Acta Biomembr. 2020 Jan 17;1862(5):183197. doi: 10.1016/j.bbamem.2020.183197. Epub ahead of print. PMID: 31958435.

PubMed ID: 31958435

Karanth S, Delcea M. Nitrosative stress affects the interaction of integrin alphaIIbbeta3 with its ligands. Biochim Biophys Acta Biomembr. 2020 Jan 17:183198. doi: 10.1016/j.bbamem.2020.183198. Epub ahead of print. PMID: 31958436.

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Schmidt ML, Davis JH. 2 H NMR of oriented phospholipid/cholesterol bilayers containing an amphiphilic peptide. Biochim Biophys Acta Biomembr. 2020 Jan 18;1862(5):183196. doi: 10.1016/j.bbamem.2020.183196. Epub ahead of print. PMID: 31958437.

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PubMed ID: 31868187

Wong P, Li L, Chea J, Hu W, Poku E, Ebner T, Bowles N, Wong JYC, Yazaki PJ, Sligar S, Shively JE. Antibody Targeted PET Imaging of 64Cu-DOTA-Anti-CEA PEGylated Lipid Nanodiscs in CEA Positive Tumors. Bioconjug Chem. 2020 Jan 30:10.1021/acs.bioconjchem.9b00854. doi: 10.1021/acs.bioconjchem.9b00854. Epub ahead of print. PMID: 31961138.

PubMed ID: 31961138

Peterka O, Jirásko R, Chocholoušková M, Kuchař L, Wolrab D, Hájek R, Vrána D, Strouhal O, Melichar B, Holčapek M. Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jan 21;1865(5):158634. doi: 10.1016/j.bbalip.2020.158634. Epub ahead of print. PMID: 31978556.

PubMed ID: 31978556

Kim HY, Cheon JH, Lee SH, Min JY, Back SY, Song JG, Kim DH, Lim SJ, Han HK. Ternary nanocomposite carriers based on organic clay-lipid vesicles as an effective colon-targeted drug delivery system: preparation and in vitro/in vivo characterization. J Nanobiotechnology. 2020 Jan 21;18(1):17. doi: 10.1186/s12951-020-0579-7. PMID: 31964393; PMCID: PMC6975051.

PubMed ID: 31964393

He W, Evans AC, Rasley A, Bourguet F, Peters S, Kamrud KI, Wang N, Hubby B, Felderman M, Gouvis H, Coleman MA, Fischer NO. Cationic HDL mimetics enhance in vivo delivery of self-replicating mRNA. Nanomedicine. 2020 Jan 24;24:102154. doi: 10.1016/j.nano.2020.102154. Epub ahead of print. PMID: 31982617.

PubMed ID: 31982617

Lebègue E, Barrière F, Bard AJ. Lipid Membrane Permeability of Synthetic Redox DMPC Liposomes Investigated by Single Electrochemical Collisions. Anal Chem. 2020 Feb 4;92(3):2401-2408. doi: 10.1021/acs.analchem.9b02809. Epub 2020 Jan 21. PMID: 31916438.

PubMed ID: 31916438

Han L, Kitov PI, Li J, Kitova EN, Klassen JS. Probing Heteromultivalent Protein-Glycosphingolipid Interactions using Native Mass Spectrometry and Nanodiscs. Anal Chem. 2020 Feb 12:10.1021/acs.analchem.9b05419. doi: 10.1021/acs.analchem.9b05419. Epub ahead of print. PMID: 31944669.

PubMed ID: 31944669

Zhou S, Huang Y, Chen Y, Liu S, Xu M, Jiang T, Song Q, Jiang G, Gu X, Gao X, Chen J. Engineering ApoE3-incorporated biomimetic nanoparticle for efficient vaccine delivery to dendritic cells via macropinocytosis to enhance cancer immunotherapy. Biomaterials. 2020 Mar;235:119795. doi: 10.1016/j.biomaterials.2020.119795. Epub 2020 Jan 16. PMID: 32014739.

PubMed ID: 32014739

Ahn SI, Sei YJ, Park HJ, Kim J, Ryu Y, Choi JJ, Sung HJ, MacDonald TJ, Levey AI, Kim Y. Microengineered human blood-brain barrier platform for understanding nanoparticle transport mechanisms. Nat Commun. 2020 Jan 10;11(1):175. doi: 10.1038/s41467-019-13896-7. PMID: 31924752; PMCID: PMC6954233.

PubMed ID: 31924752

Li Q, Li S, Zhang X, Xu W, Han X. Programmed magnetic manipulation of vesicles into spatially coded prototissue architectures arrays. Nat Commun. 2020 Jan 13;11(1):232. doi: 10.1038/s41467-019-14141-x. PMID: 31932592; PMCID: PMC6957477.

PubMed ID: 31932592

Jiang T, Hall A, Eres M, Hemmatian Z, Qiao B, Zhou Y, Ruan Z, Couse AD, Heller WT, Huang H, de la Cruz MO, Rolandi M, Xu T. Single-chain heteropolymers transport protons selectively and rapidly. Nature. 2020 Jan;577(7789):216-220. doi: 10.1038/s41586-019-1881-0. Epub 2020 Jan 8. PMID: 31915399.

PubMed ID: 31915399

Okabe M, Taga K, Yoshino A, Yamamoto Y, Taneda A, Shinoda S, Kanamasa S, Shervani Z. Effect of Escherichia coli on phospholipid monolayers: surface tensiometry and Brewster angle microscopy measurements. Eur Biophys J. 2020 Jan;49(1):71-84. doi: 10.1007/s00249-019-01413-z. Epub 2019 Dec 20. PMID: 31863194.

PubMed ID: 31863194

Lone A, Thomsen TT, Nielsen JE, Thulstrup PW, Klitgaard RN, Løbner-Olesen A, Lund R, Jenssen H, Hansen PR. Structure-Activity Study of an All-d Antimicrobial Octapeptide D2D. Molecules. 2019 Dec 13;24(24):4571. doi: 10.3390/molecules24244571. PMID: 31847173; PMCID: PMC6943423.

PubMed ID: 31847173

Asamoto DK, Kang G, Kim JE. Folding of the β-Barrel Membrane Protein OmpA into Nanodiscs. Biophys J. 2020 Jan 21;118(2):403-414. doi: 10.1016/j.bpj.2019.11.3381. Epub 2019 Nov 28. PMID: 31843264; PMCID: PMC6976806.

PubMed ID: 31843264

Staton JA, Stearns SW, Dungan SR. Mechanism of Time-Dependent Adsorption for Phosphatidylcholine onto a Clean Air-Water Interface from a Dispersion of Vesicles: Effect of Temperature and Acyl Chain Length. Langmuir. 2019 Dec 24;35(51):16850-16861. doi: 10.1021/acs.langmuir.9b02904. Epub 2019 Dec 9. PMID: 31815494.

PubMed ID: 31815494

Lubbers R, Oostindie SC, Dijkstra DJ, Parren PWHI, Verheul MK, Abendstein L, Sharp TH, de Ru A, Janssen GMC, van Veelen PA, van den Bremer ETJ, Bleijlevens B, de Kreuk BJ, Beurskens FJ, Trouw LA. Carbamylation reduces the capacity of IgG for hexamerization and complement activation. Clin Exp Immunol. 2019 Dec 19;10.1111/cei.13411. doi: 10.1111/cei.13411. [Epub ahead of print]. PMID: 31853959.

PubMed ID: 31853959

Mias-Lucquin D, Dos Santos Morais R, Chéron A, Lagarrigue M, Winder SJ, Chenuel T, Pérez J, Appavou MS, Martel A, Alviset G, Le Rumeur E, Combet S, Hubert JF, Delalande O. How the central domain of dystrophin acts to bridge F-actin to sarcolemmal lipids. J Struct Biol. 2020 Jan 1;209(1):107411. doi: 10.1016/j.jsb.2019.107411. Epub 2019 Nov 2. PMID: 31689503.

PubMed ID: 31689503

Konstantinidi A, Chountoulesi M, Naziris N, Sartori B, Amenitsch H, Mali G, Čendak T, Plakantonaki M, Triantafyllakou I, Tselios T, Demetzos C, Busath DD, Mavromoustakos T, Kolocouris A. The boundary lipid around DMPC-spanning influenza A M2 transmembrane domain channels: Its structure and potential for drug accommodation. Biochim Biophys Acta Biomembr. 2020 Mar 1;1862(3):183156. doi: 10.1016/j.bbamem.2019.183156. Epub 2019 Dec 14. PMID: 31846647.

PubMed ID: 31846647

Sou K, Chan LY, Arai S, Lee CK. Highly cooperative fluorescence switching of self-assembled squaraine dye at tunable threshold temperatures using thermosensitive nanovesicles for optical sensing and imaging. Sci Rep. 2019 Nov 29;9(1):17991. doi: 10.1038/s41598-019-54418-1. PMID: 31784685; PMCID: PMC6884458.

PubMed ID: 31784685

Hussain MT, Forbes N, Perrie Y, Malik KP, Duru C, Matejtschuk P. Freeze-drying cycle optimization for the rapid preservation of protein-loaded liposomal formulations. Int J Pharm. 2020 Jan 5;573:118722. doi: 10.1016/j.ijpharm.2019.118722. Epub 2019 Nov 6. PMID: 31705976.

PubMed ID: 31705976

Verma A, Schmidt BA, Elizaldi SR, Nguyen NK, Walter KA, Beck Z, Trinh HV, Dinsarapu AR, Lakshmanappa YS, Rane NN, Matyas GR, Rao M, Shen X, Tomaras GD, LaBranche CC, Reimann KA, Foehl DH, Gach JS, Forthal DN, Kozlowski PA, Amara RR, Iyer SS. Impact of Th1 CD4 TFH skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. J Virol. 2019 Dec 11;JVI.01737-19. doi: 10.1128/JVI.01737-19. [Epub ahead of print]. PMID: 31827000.

PubMed ID: 31827000

Konopko A, Kusio J, Litwinienko G. Antioxidant Activity of Metal Nanoparticles Coated with Tocopherol-Like Residues-The Importance of Studies in Homo- and Heterogeneous Systems. Antioxidants (Basel). 2019 Dec 19;9(1):E5. doi: 10.3390/antiox9010005. PMID: 31861581.

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Li H, Song Y, Zhang H, Wang X, Cong P, Xu J, Xue C. Comparative lipid profile of four edible shellfishes by UPLC-Triple TOF-MS/MS. Food Chem. 2020 Apr 25;310:125947. doi: 10.1016/j.foodchem.2019.125947. Epub 2019 Dec 4. PMID: 31841939.

PubMed ID: 31841939

Nordström R, Browning KL, Parra-Ortiz E, Damgaard LSE, Häffner SM, Maestro A, Campbell RA, Cooper JFK, Malmsten M. Membrane interactions of antimicrobial peptide-loaded microgels. J Colloid Interface Sci. 2020 Mar 7;562:322-332. doi: 10.1016/j.jcis.2019.12.022. Epub 2019 Dec 9. PMID: 31855795.

PubMed ID: 31855795

Momtazi-Borojeni AA, Jaafari MR, Badiee A, Banach M, Sahebkar A. Therapeutic effect of nanoliposomal PCSK9 vaccine in a mouse model of atherosclerosis. BMC Med. 2019;17(1):223. Published 2019 Dec 10. doi:10.1186/s12916-019-1457-8

PubMed ID: 31818299

Pinheiro M, Amenitsch H, Reis S. Antituberculosis Drug Interactions with Membranes: A Biophysical Approach Applied to Bedaquiline. Membranes (Basel). 2019 Oct 30;9(11). pii: E141. doi: 10.3390/membranes9110141.

PubMed ID: 31671599

Shi D, Nguyen DV, Maaloum M, Gallani JL, Felder-Flesch D, Krafft MP. Interfacial Behavior of Oligo(Ethylene Glycol) Dendrons Spread Alone and in Combination with a Phospholipid as Langmuir Monolayers at the Air/Water Interface. Molecules. 2019 Nov 14;24(22). pii: E4114. doi: 10.3390/molecules24224114.

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Pérez-Isidoro R, Ruiz-Suárez JC. Thermal behavior of a lipid-protein membrane model and the effects produced by anesthetics and neurotransmitters. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183099. doi: 10.1016/j.bbamem.2019.183099. Epub 2019 Nov 4.

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Sustich SJ, Afrose F, Greathouse DV, Koeppe RE 2nd. Influence of interfacial tryptophan residues on an arginine-flanked transmembrane helix. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183134. doi: 10.1016/j.bbamem.2019.183134. Epub 2019 Nov 16.

PubMed ID: 31738898

Perczyk P, Wójcik A, Wydro P, Broniatowski M. The role of phospholipid composition and ergosterol presence in the adaptation of fungal membranes to harsh environmental conditions-membrane modeling study. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183136. doi: 10.1016/j.bbamem.2019.183136. Epub 2019 Nov 18.

PubMed ID: 31751523

Mücksch F, Citir M, Lüchtenborg C, Glass B, Traynor-Kaplan A, Schultz C, Brügger B, Kräusslich HG. Quantification of phosphoinositides reveals strong enrichment of PIP2 in HIV-1 compared to producer cell membranes. Sci Rep. 2019 Nov 27;9(1):17661. doi: 10.1038/s41598-019-53939-z.

PubMed ID: 31776383

Muhanna N, Chan H, Townson JL, Jin CS, Ding L, Valic M, Douglas CM, Maclaughlin CM, Chen J, Zheng G, Irish JC. Photodynamic therapy enables tumor specific ablation in preclinical models of thyroid cancer. Endocr Relat Cancer. 2019 Nov 1. pii: ERC-19-0258.R2. doi: 10.1530/ERC-19-0258. [Epub ahead of print]

PubMed ID: 31751308

Bratanov D, Kovalev K, Machtens JP, Astashkin R, Chizhov I, Soloviov D, Volkov D, Polovinkin V, Zabelskii D, Mager T, Gushchin I, Rokitskaya T, Antonenko Y, Alekseev A, Shevchenko V, Yutin N, Rosselli R, Baeken C, Borshchevskiy V, Bourenkov G, Popov A, Balandin T, Büldt G, Manstein DJ, Rodriguez-Valera F, Fahlke C, Bamberg E, Koonin E, Gordeliy V. Unique structure and function of viral rhodopsins. Nat Commun. 2019 Oct 30;10(1):4939. doi: 10.1038/s41467-019-12718-0.

PubMed ID: 3166521

Handumrongkul C, Ye AL, Chmura SA, Soroceanu L, Mack M, Ice RJ, Thistle R, Myers M, Ursu SJ, Liu Y, Kashani-Sabet M, Heath TD, Liggitt D, Lewis DB, Debs R. Durable multitransgene expression in vivo using systemic, nonviral DNA delivery. Sci Adv. 2019 Nov 27;5(11):eaax0217. doi: 10.1126/sciadv.aax0217. eCollection 2019 Nov.

PubMed ID: 31807699

Pinto P, Machado CM, Moreira J, Almeida JDP, Silva PMA, Henriques AC, Soares JX, Salvador JAR, Afonso C, Pinto M, Bousbaa H, Cidade H. Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity. Eur J Med Chem. 2019 Dec 15;184:111752. doi: 10.1016/j.ejmech.2019.111752. Epub 2019 Oct 3.

PubMed ID: 31610374

Mirtaheri E, Dolatmoradi A, El-Zahab B. Thermally Assisted Acoustofluidic Separation Based on Membrane Protein Content. Anal Chem. 2019 Nov 5;91(21):13953-13961. doi: 10.1021/acs.analchem.9b03485. Epub 2019 Oct 25.

PubMed ID: 31590489

Leninger M, Sae Her A, Traaseth NJ. Inducing conformational preference of the membrane protein transporter EmrE through conservative mutations. Elife. 2019 Oct 22;8. pii: e48909. doi: 10.7554/eLife.48909.

PubMed ID: 31637997

Kapsalis C, Wang B, El Mkami H, Pitt SJ, Schnell JR, Smith TK, Lippiat JD, Bode BE, Pliotas C. Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets. Nat Commun. 2019 Oct 10;10(1):4619. doi: 10.1038/s41467-019-12591-x.

PubMed ID: 31601809

Nirod Kumar Sarangi and Jaydeep Kumar Basu. Preferential binding and re-organization of nanoscale domains on model lipid membranes by pore-forming toxins: insight from STED-FCS. Journal of Physics D: Applied Physics, Volume 52, Number 50.


McKay MJ, Fu R, Greathouse DV, Koeppe RE. Breaking the Backbone: Central Arginine Residues Induce Membrane Exit and Helix Distortions within a Dynamic Membrane Peptide. J Phys Chem B. 2019 Sep 26;123(38):8034-8047. doi: 10.1021/acs.jpcb.9b06034. Epub 2019 Sep 17.

PubMed ID: 31483653

Lopes D, Melo T, Meneses J, Abreu MH, Pereira R, Domingues P, Lillebø AI, Calado R, Domingues MR. A New Look for the Red Macroalga Palmaria palmata: A Seafood with Polar Lipids Rich in EPA and with Antioxidant Properties. Mar Drugs. 2019 Sep 13;17(9). pii: E533. doi: 10.3390/md17090533.

PubMed ID: 31540326

Wójcik P, Biernacki M, Wroński A, Łuczaj W, Waeg G, Žarković N, Skrzydlewska E. Altered Lipid Metabolism in Blood Mononuclear Cells of Psoriatic Patients Indicates Differential Changes in Psoriasis Vulgaris and Psoriatic Arthritis. Int J Mol Sci. 2019 Aug 30;20(17). pii: E4249. doi: 10.3390/ijms20174249.

PubMed ID: 31480263

Pedersbæk D, Kræmer MK, Kempen PJ, Ashley J, Braesch-Andersen S, Andresen TL, Simonsen JB. The Composition of Reconstituted High-Density Lipoproteins (rHDL) Dictates the Degree of rHDL Cargo- and Size-Remodeling via Direct Interactions with Endogenous Lipoproteins. Bioconjug Chem. 2019 Oct 16;30(10):2634-2646. doi: 10.1021/acs.bioconjchem.9b00552. Epub 2019 Sep 19.

PubMed ID: 31487985

Smriti Sultana, Binte Mustafiz, Toru Uyama, Katsuya Morito, Naoko Takahashi, Katsuhisa Kawai, Zahir Hussain, Kazuhito Tsuboi, Nobukazu Araki, Kei Yamamoto, Tamotsu Tanaka, Natsuo Ueda. Intracellular Ca2+-dependent formation of N-acyl-phosphatidylethanolamines by human cytosolic phospholipase A2ε. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2019 December;1864:12,158515. doi: 10.1016/j.bbalip.2019.158515


Schwartz AC, Jay DW, Parnham S, Giuliano MW. Sequential and Environmental Dependence of Conformation in a Small Opioid Peptide. J Org Chem. 2019 Oct 15. doi: 10.1021/acs.joc.9b01141. [Epub ahead of print]

PubMed ID: 31538782

Zinger A, Koren L, Adir O, Poley M, Alyan M, Yaari Z, Noor N, Krinsky N, Simon A, Gibori H, Krayem M, Mumblat Y, Kasten S, Ofir S, Fridman E, Milman N, Lübtow MM, Liba L, Shklover J, Shainsky-Roitman J, Binenbaum Y, Hershkovitz D, Gil Z, Dvir T, Luxenhofer R, Satchi-Fainaro R, Schroeder A. Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors. ACS Nano. 2019 Sep 20. doi: 10.1021/acsnano.9b02395. [Epub ahead of print]

PubMed ID: 31503443

Tasso TT, Schlothauer JC, Junqueira HC, Matias TA, Araki K, Liandra-Salvador É, Antonio FCT, Homem-de-Mello P, Baptista MS. Photobleaching Efficiency Parallels the Enhancement of Membrane Damage for Porphyrazine Photosensitizers. J Am Chem Soc. 2019 Oct 2;141(39):15547-15556. doi: 10.1021/jacs.9b05991. Epub 2019 Sep 18.

PubMed ID: 31490678

Eddy MT, Yu TY, Wagner G, Griffin RG. Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR. J Biomol NMR. 2019 Aug 12. doi: 10.1007/s10858-019-00242-8. [Epub ahead of print]

PubMed ID: 31407201

Bose D, Chakrabarti A. Chaperone potential of erythroid spectrin: Effects of hemoglobin interaction, macromolecular crowders, phosphorylation and glycation. Biochim Biophys Acta Proteins Proteom. 2019 Nov;1867(11):140267. doi: 10.1016/j.bbapap.2019.140267. Epub 2019 Aug 27.

PubMed ID: 31470132

Dushianthan A, Cusack R, Koster G, Grocott MPW, Postle AD. Insight into erythrocyte phospholipid molecular flux in healthy humans and in patients with acute respiratory distress syndrome. PLoS One. 2019 Aug 27;14(8):e0221595. doi: 10.1371/journal.pone.0221595. eCollection 2019.

PubMed ID: 31454387

Szymkowicz L, Lento C, Wilson DJ. Impact of Cardiolipin and Phosphatidylcholine Interactions on the Conformational Ensemble of Cytochrome c. Biochemistry. 2019 Aug 27;58(34):3617-3626. doi: 10.1021/acs.biochem.9b00495. Epub 2019 Aug 12.

PubMed ID: 31380624

Sharma VK, Nagao M, Rai DK, Mamontov E. Membrane softening by nonsteroidal anti-inflammatory drugs investigated by neutron spin echo. Phys Chem Chem Phys. 2019 Sep 18;21(36):20211-20218. doi: 10.1039/c9cp03767e.

PubMed ID: 31486459

Wang X, Zhang H, Song Y, Cong P, Li Z, Xu J, Xue C. Comparative Lipid Profile Analysis of Four Fish Species by Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry. J Agric Food Chem. 2019 Aug 21;67(33):9423-9431. doi: 10.1021/acs.jafc.9b03303. Epub 2019 Aug 8.

PubMed ID: 31329442

Marchioro L, Geraghty AA, Uhl O, Shokry E, O'Brien EC, Koletzko B, McAuliffe FM. Effect of a low glycaemic index diet during pregnancy on maternal and cord blood metabolomic profiles: results from the ROLO randomized controlled trial. Nutr Metab (Lond). 2019 Aug 27;16:59. doi: 10.1186/s12986-019-0378-z. eCollection 2019.

PubMed ID: 31467584

Chervy P, Petcut C, Rault D, Meriadec C, Bizien T, François K, Richard J, Chassaing C, Benamar N, Artzner F, Paternostre M. Organic Nanoscrolls from Electrostatic Interactions between Peptides and Lipids: Assembly Steps and Structure. Langmuir. 2019 Aug 13;35(32):10648-10657. doi: 10.1021/acs.langmuir.9b01542. Epub 2019 Aug 2.

PubMed ID: 31330110

Hamano N, Böttger R, Lee SE, Yang Y, Kulkarni JA, Ip S, Cullis PR, Li SD. Robust Microfluidic Technology and New Lipid Composition for Fabrication of Curcumin-Loaded Liposomes: Effect on the Anticancer Activity and Safety of Cisplatin. Mol Pharm. 2019 Sep 3;16(9):3957-3967. doi: 10.1021/acs.molpharmaceut.9b00583. Epub 2019 Aug 16.

PubMed ID: 31381352

Garcia Ribeiro RS, Belderbos S, Danhier P, Gallo J, Manshian BB, Gallez B, Bañobre M, de Cuyper M, Soenen SJ, Gsell W, Himmelreich U. Targeting tumor cells and neovascularization using RGD-functionalized magnetoliposomes. Int J Nanomedicine. 2019 Jul 29;14:5911-5924. doi: 10.2147/IJN.S214041. eCollection 2019.

PubMed ID: 31534330

Chen L, Ma MY, Sun M, Jiang LY, Zhao XT, Fang XX, Man Lam S, Shui GH, Luo J, Shi XJ, Song BL. Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing. J Lipid Res. 2019 Oct;60(10):1765-1775. doi: 10.1194/jlr.RA119000201. Epub 2019 Aug 27.

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Mason C, Kossatz S, Carter L, Pirovano G, Brand C, Guru N, Pérez-Medina C, Lewis JS, Mulder W, Reiner T. A 89Zr-HDL PET tracer monitors response to a CSF1R inhibitor. J Nucl Med. 2019 Aug 16. pii: jnumed.119.230466. doi: 10.2967/jnumed.119.230466. [Epub ahead of print]

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Chung KP, Hsu CL, Fan LC, Huang Z, Bhatia D, Chen YJ, Hisata S, Cho SJ, Nakahira K, Imamura M, Choi ME, Yu CJ, Cloonan SM, Choi AMK. Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis. Nat Commun. 2019 Jul 29;10(1):3390. doi: 10.1038/s41467-019-11327-1.

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Mulvihill E, Pfreundschuh M, Thoma J, Ritzmann N, Müller DJ. High-Resolution Imaging of Maltoporin LamB while Quantifying the Free-Energy Landscape and Asymmetry of Sugar Binding. Nano Lett. 2019 Sep 11;19(9):6442-6453. doi: 10.1021/acs.nanolett.9b02674. Epub 2019 Aug 12.

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Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM. Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species. Sci Transl Med. 2019 Aug 21;11(506). pii: eaaw7736. doi: 10.1126/scitranslmed.aaw7736.

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Sumino A, Sumikama T, Uchihashi T, Oiki S. High-speed AFM reveals accelerated binding of agitoxin-2 to a K+ channel by induced fit. Sci Adv. 2019 Jul 3;5(7):eaax0495. doi: 10.1126/sciadv.aax0495. eCollection 2019 Jul.

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Lin WS, Malmstadt N. Liposome production and concurrent loading of drug simulants by microfluidic hydrodynamic focusing. Eur Biophys J. 2019 Sep;48(6):549-558. doi: 10.1007/s00249-019-01383-2. Epub 2019 Jul 20.

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Liu J, Zhu L, Zhang X, Wu B, Zhu P, Zhao H, Wang J. Peptide-based NTA(Ni)-nanodiscs for studying membrane enhanced FGFR1 kinase activities. PeerJ. 2019 Jul 23;7:e7234. doi: 10.7717/peerj.7234. eCollection 2019.

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Ghellab SE, Mu W, Li Q, Han X. Prediction of the size of electroformed giant unilamellar vesicle using response surface methodology. Biophys Chem. 2019 Oct;253:106217. doi: 10.1016/j.bpc.2019.106217. Epub 2019 Jul 4.

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Shukla SD, Restrepo R, Aroor AR, Liu X, Lim RW, Franke JD, Ford DA, Korthuis RJ. Binge Alcohol Is More Injurious to Liver in Female than in Male Rats: Histopathological, Pharmacologic, and Epigenetic Profiles. J Pharmacol Exp Ther. 2019 Sep;370(3):390-398. doi: 10.1124/jpet.119.258871. Epub 2019 Jul 1.

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Ghosh S, Sil TB, Dolai S, Garai K. High-affinity multivalent interactions between apolipoprotein E and the oligomers of amyloid-β. FEBS J. 2019 Jul 9. doi: 10.1111/febs.14988. [Epub ahead of print]

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Crihfield CL, Kristoff CJ, Veltri LM, Penny WM, Holland LA. Semi-permanent cationic coating for protein separations. J Chromatogr A. 2019 Jul 25:460397. doi: 10.1016/j.chroma.2019.460397. [Epub ahead of print]

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Wolde-Kidan A, Pham QD, Schlaich A, Loche P, Sparr E, Netz RR, Schneck E. Influence of polar co-solutes and salt on the hydration of lipid membranes. Phys Chem Chem Phys. 2019 Aug 21;21(31):16989-17000. doi: 10.1039/c9cp01953g. Epub 2019 Jul 25.

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Varenne F, Coty JB, Botton J, Legrand FX, Hillaireau H, Barratt G, Vauthier C. Evaluation of zeta potential of nanomaterials by electrophoretic light scattering: Fast field reversal versus Slow field reversal modes. Talanta. 2019 Dec 1;205:120062. doi: 10.1016/j.talanta.2019.06.062. Epub 2019 Jun 18.

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Dang AT, He W, Ivey DB, Coleman MA, Kuhl TL. Lipid and Protein Transfer between Nanolipoprotein Particles and Supported Lipid Bilayers. Langmuir. 2019 Sep 6. doi: 10.1021/acs.langmuir.9b01288. [Epub ahead of print]

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Pandidan S, Mechler A. Nano-viscosimetry analysis of the membrane disrupting action of the bee venom peptide melittin. Sci Rep. 2019 Jul 25;9(1):10841. doi: 10.1038/s41598-019-47325-y.

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Park J, Kuo Y, Li J, Huang YL, Miller EW, Weiss S. Improved Surface Functionalization and Characterization of Membrane-Targeted Semiconductor Voltage Nanosensors. J Phys Chem Lett. 2019 Jul 18;10(14):3906-3913. doi: 10.1021/acs.jpclett.9b01258. Epub 2019 Jul 1.

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Zhao Y, You SS, Zhang A, Lee JH, Huang J, Lieber CM. Scalable ultrasmall three-dimensional nanowire transistor probes for intracellular recording. Nat Nanotechnol. 2019 Aug;14(8):783-790. doi: 10.1038/s41565-019-0478-y. Epub 2019 Jul 1.

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Jesaitis AJ, Riesselman M, Taylor RM, Brumfield S. Enhanced Immunoaffinity Purification of Human Neutrophil Flavocytochrome B for Structure Determination by Electron Microscopy. Methods Mol Biol. 2019;1982:39-59. doi: 10.1007/978-1-4939-9424-3_3.

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Zhou H, Lei X, Yan Y, Lydic T, Li J, Weintraub NL, Su H, Chen W. Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy. JCI Insight. 2019 Jun 11;5. pii: 129781. doi: 10.1172/jci.insight.129781.

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Kohei Morita , Miki Horikoshi , Tamami Yanagi , Toshiyuki Takagi , Hiroshi Takahashi , Hideki Amii , Takeshi Hasegawa , and Masashi Sonoyama. Thermotropic Transition Behaviors of Novel Partially Fluorinated Dimyristoylphosphatidylcholines with Different Perfluoroalkyl Chain Lengths. CSJ Journals. doi: 10.1246/cl.190389


Greathouse D, Lipinski K, McKay MJ, Afrose F, Martfeld AN, Koeppe RE 2nd. Influence of Lipid Saturation, Hydrophobic Length and Cholesterol on Double-Arginine-Containing Helical Peptides in Bilayer Membranes. Chembiochem. 2019 May 31. doi: 10.1002/cbic.201900282. [Epub ahead of print]

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Gryz E, Perlińska-Lenart U, Gawarecka K, Jozwiak A, Piłsyk S, Lipko A, Jemiola-Rzeminska M, Bernat P, Muszewska A, Steczkiewicz K, Ginalski K, Długoński J, Strzalka K, Swiezewska E, Kruszewska JS. Poly-Saturated Dolichols from Filamentous Fungi Modulate Activity of Dolichol-Dependent Glycosyltransferase and Physical Properties of Membranes. Int J Mol Sci. 2019 Jun 21;20(12). pii: E3043. doi: 10.3390/ijms20123043.

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Mauceri A, Giansanti L, Bozzuto G, Condello M, Molinari A, Galantini L, Piozzi A, Mancini G. Structurally related glucosylated liposomes: Correlation of physicochemical and biological features. Biochim Biophys Acta Biomembr. 2019 Aug 1;1861(8):1468-1475. doi: 10.1016/j.bbamem.2019.06.003. Epub 2019 Jun 10.

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Singh P, Bodycomb J, Travers B, Tatarkiewicz K, Travers S, Matyas GR, Beck Z. Particle size analyses of polydisperse liposome formulations with a novel multispectral advanced nanoparticle tracking technology. Int J Pharm. 2019 Jul 20;566:680-686. doi: 10.1016/j.ijpharm.2019.06.013. Epub 2019 Jun 6.

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F. Varenne, J.-B.Coty, J.Botton, F.-X. Legrand, H. Hillaireau, G. Barratt, C. Vauthier. Evaluation of zeta potential of nanomaterials by electrophoretic light scattering: Fast field reversal versus Slow field reversal modes. Talanta. 1 December 2019;205:120062. doi: 10.1016/j.talanta.2019.06.062.


Manu V. S., Tata Gopinath, Songlin Wang, & Gianluigi Veglia. T2* weighted Deconvolution of NMR Spectra: Application to 2D Homonuclear MAS Solid-State NMR of Membrane Proteins. Nature. Scientific Reports. 03 June 2019;9:8225. doi: 10.1038/s41598-019-44461-3.


Ni Z, Sousa BC, Colombo S, Afonso CB, Melo T, Pitt AR, Spickett CM, Domingues P, Domingues MR, Fedorova M, Criscuolo A. Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS. Free Radic Biol Med. 2019 Jun 15. pii: S0891-5849(19)30347-8. doi: 10.1016/j.freeradbiomed.2019.06.013. [Epub ahead of print]

PubMed ID: 31212065

Walker LR, Marzluff EM, Townsend JA, Resager WC, Marty MT. Native Mass Spectrometry of Antimicrobial Peptides in Lipid Nanodiscs Elucidates Complex Assembly. Anal Chem. 2019 Jul 16;91(14):9284-9291. doi: 10.1021/acs.analchem.9b02261. Epub 2019 Jun 28.

PubMed ID: 31251560

Momtazi-Borojeni AA, Nik ME, Jaafari MR, Banach M, Sahebkar A. Potential anti-tumor effect of a nanoliposomal antiPCSK9 vaccine in mice bearing colorectal cancer. Arch Med Sci. 2019 May;15(3):559-569. doi: 10.5114/aoms.2019.84732. Epub 2019 Apr 30.

PubMed ID: 31110520

Camuri IJ, da Costa AB, Ito AS, Moreira Pazin W. pH and Charge Effects Behind the Interaction of Artepillin C, the Major Component of Green Propolis, With Amphiphilic Aggregates: Optical Absorption and Fluorescence Spectroscopy Studies. Photochem Photobiol. 2019 May 21. doi: 10.1111/php.13128. [Epub ahead of print]

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Yang W, Lee JS, Leninger M, Windschuh J, Traaseth NJ, Jerschow A. Magnetization transfer in liposome and proteoliposome samples that mimic the protein and lipid composition of myelin. NMR Biomed. 2019 Jul;32(7):e4097. doi: 10.1002/nbm.4097. Epub 2019 May 6.

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Henderson JM, Iyengar NS, Lam KLH, Maldonado E, Suwatthee T, Roy I, Waring AJ, Lee KYC. Beyond electrostatics: Antimicrobial peptide selectivity and the influence of cholesterol-mediated fluidity and lipid chain length on protegrin-1 activity. Biochim Biophys Acta Biomembr. 2019 May 8. pii: S0005-2736(19)30090-2. doi: 10.1016/j.bbamem.2019.04.011. [Epub ahead of print]

PubMed ID: 31077677

Henderson JM, Iyengar NS, Lam KLH, Maldonado E, Suwatthee T, Roy I, Waring AJ, Lee KYC. Beyond electrostatics: Antimicrobial peptide selectivity and the influence of cholesterol-mediated fluidity and lipid chain length on protegrin-1 activity. Biochim Biophys Acta Biomembr. 2019 May 8. pii: S0005-2736(19)30090-2. doi: 10.1016/j.bbamem.2019.04.011. [Epub ahead of print]

PubMed ID: 31077677

Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol