850338 | MAPCHO®-14

n-tetradecylphosphocholine


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1g 850338P-1g 850338P-1g 1 x 1g $226.00
10g 850338P-10g 850338P-10g 1 x 10g $1,596.00
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MAPCHO®-14

MAPCHO®-14

n-tetradecylphosphocholine

Tetradecylphosphocholine is a structural analog of myristoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification. It has been used as a helper lipid for in vitro and in vivo gene transfer, and it has been shown to have some anticancer activity.
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C19H42NO4P
Percent Composition
C 60.13%, H 11.15%, N 3.69%, O 16.86%, P 8.16%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
77733-28-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
379.515
Exact Mass
379.285
Synonyms
<p>TPCFos-Choline-14FOS14FC-14</p>
Göbl, C., Dulle, M., Hohlweg, W., Grossauer, J., Falsone, S.F., Glatter, O., Zangger, K. (2010) Influence of phosphocholine alkyl chain length on peptide-micelle interactions and micellar size and shape. J Phys Chem B. 114:4717-24. [PubMed] Koehler, J., Sulistijo, E.S., Sakakura, M., Kim, H.J., Ellis, C.D., Sanders, C.R. (2010) Lysophospholipid micelles sustain the stability and catalytic activity of diacylglycerol kinase in the absence of lipids.Biochemistry. 49:7089-99. [PubMed] Vernier, G., Wang, J., Jennings, L.D., Sun, J., Fischer, A., Song, L., Collier, R.J. (2009) Solubilization and characterization of the anthrax toxin pore in detergent micelles. Protein Sci. 18:1882-95. [PubMed] Cook, B.L., Ernberg, K.E., Chung, H., Zhang, S. (2008)Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line. PLoS One. 3:e2920. [PubMed] Zeisig, R., Ress, A., Fichtner, I., Walther, W. (2003) Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy. Cancer Gene Ther. 10:302-11. [PubMed]