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MAPCHO®-10 | 850334





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n-decylphosphocholine is a structural analog of decanoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid maybe used as a detergent for membrane protein solubilization and purification.
Molecular Formula
Percent Composition
C 55.71%, H 10.60%, N 4.33%, O 19.79%, P 9.58%
1 Years
CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
Exact Mass
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Horst, R., P. Stanczak, P. Serrano, and K. Wuthrich. (2012). Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solubilized membrane protein OmpX. J Phys Chem B 116:6775-80. [PubMed]Palladino, P., Rossi, F., Ragone, R. (2010) Effective critical micellar concentration of a zwitterionic detergent: a fluorimetric study on n-dodecyl phosphocholine. J Fluoresc. 20:191-6. [PubMed]Vasudevan, S.V., Schulz, J., Zhou, C., Cocco, M.J. (2010) Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface. Proc Natl Acad Sci U S A. 107:6847-51. [PubMed]Liang, B., Tamm, L.K. (2007) Structure of outer membrane protein G by solution NMR spectroscopy. Proc Natl Acad Sci U S A. 104:16140-5. [PubMed]Brunecky, R., Lee, S., Rzepecki, P.W., Overduin, M., Prestwich, G.D., Kutateladze, A.G., Kutateladze, T.G. (2005) Investigation of the binding geometry of a peripheral membrane protein. Biochemistry. 44:16064-71. [PubMed]Liu, D.Z., LeCluyse, E.L., Thakker, D.R. (1999) Dodecylphosphocholine-mediated enhancement of paracellular permeability and cytotoxicity in Caco-2 cell monolayers. J Pharm Sci. 88:1161-8. [PubMed]