850334 | MAPCHO®-10

n-decylphosphocholine


Powder

Size SKU Packaging Price
1g 850334P-1g 850334P-1g 1 x 1g $243.23
Base Price: ${originalprice|money}
Custom Packaging: (${concentration} @$4.00/ea. + $100) ${custompackagingtotal|money}
Packaging: ${concentration}
Item Total: ${totalprice|money}
(Sales Tax may apply)
Please select an option above.
${sku} - ${concentration}

MAPCHO®-10

MAPCHO®-10

n-decylphosphocholine

n-decylphosphocholine is a structural analog of decanoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid maybe used as a detergent for membrane protein solubilization and purification.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C15H34NO4P
Percent Composition
C 55.71%, H 10.60%, N 4.33%, O 19.79%, P 9.58%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
70504-28-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
323.409
Exact Mass
323.223

Horst R, Stanczak P, Serrano P, Wüthrich K. Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solubilized membrane protein OmpX. J Phys Chem B. 2012 Jun 14;116(23):6775-80. doi: 10.1021/jp212401w. Epub 2012 Feb 29. PMID: 22335573; PMCID: PMC3376199.

PubMed ID: 22335573

Palladino P, Rossi F, Ragone R. Effective critical micellar concentration of a zwitterionic detergent: a fluorimetric study on n-dodecyl phosphocholine. J Fluoresc. 2010 Jan;20(1):191-6. doi: 10.1007/s10895-009-0537-0. Epub 2009 Sep 16. PMID: 19756982.

PubMed ID: 19756982

Vasudevan SV, Schulz J, Zhou C, Cocco MJ. Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6847-51. doi: 10.1073/pnas.0911817107. Epub 2010 Mar 29. PMID: 20351248; PMCID: PMC2872388.

PubMed ID: 20351248

Liang B, Tamm LK. Structure of outer membrane protein G by solution NMR spectroscopy. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16140-5. doi: 10.1073/pnas.0705466104. Epub 2007 Oct 2. PMID: 17911261; PMCID: PMC2042175.

PubMed ID: 17911261

Brunecky R, Lee S, Rzepecki PW, Overduin M, Prestwich GD, Kutateladze AG, Kutateladze TG. Investigation of the binding geometry of a peripheral membrane protein. Biochemistry. 2005 Dec 13;44(49):16064-71. doi: 10.1021/bi051127+. PMID: 16331966; PMCID: PMC2516348.

PubMed ID: 16331966

Liu DZ, LeCluyse EL, Thakker DR. Dodecylphosphocholine-mediated enhancement of paracellular permeability and cytotoxicity in Caco-2 cell monolayers. J Pharm Sci. 1999 Nov;88(11):1161-8. doi: 10.1021/js990094e. PMID: 10564065.

PubMed ID: 10564065