Products

DOCPe | 850312

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate

850312P

Powder

25 mg
$125.00
50 mg
$195.00
100 mg
$325.00
200 mg
$545.00
500 mg
$1145.00
1 g
$1935.00

850312C

Chloroform

25 mg
$110.00
50 mg
$180.00
100 mg
$310.00
200 mg
$530.00
500 mg
$1130.00
1 g
$1920.00

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Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase.
Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.
Molecular Formula
C45H86NO8P
Percent Composition
C 67.55%, H 10.83%, N 1.75%, O16.00%, P3.87%
Purity
>99%
Stability
6 Months
Storage
-20°C
CAS Number
1360461-58-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
800.140
Exact Mass
799.609
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Wang, F. and J. Liu. (2015). A Stable Lipid/TiO Interface with Headgroup-Inversed Phosphocholine and a Comparison with SiO. J Am Chem Soc [PubMed]
This study provides an alternative system for forming stable supported bilayers on TiO2, and represents the first example of interfacing inverse lipids with inorganic surfaces.
 
Perttu, E.K., A.G. Kohli, and F.C. Szoka Jr. (2012). Inverse-phosphocholine lipids: a remix of a common phospholipid. J Am Chem Soc 134:4485-8. [PubMed]