850312 | DOCPe

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate


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Size SKU Packaging Price
25mg 850312P-25mg 850312P-25mg 1 x 25mg $131.00
200mg 850312P-200mg 850312P-200mg 1 x 200mg $572.00

Chloroform

Size SKU Packaging Price
25mg 850312C-25mg 850312C-25mg 1 x 25mg 10mg/mL 2.5mL $131.00
200mg 850312C-200mg 850312C-200mg 2 x 100mg 25mg/mL 4mL $572.00
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DOCPe

DOCPe

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate

Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase.
Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C45H86NO8P
Percent Composition
C 67.55%, H 10.83%, N 1.75%, O16.00%, P3.87%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1360461-58-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
800.140
Exact Mass
799.609

Liu Y, Wang F, Liu J. Headgroup-Inversed Liposomes: Biointerfaces, Supported Bilayers and Applications. Langmuir. 2018 Aug 14;34(32):9337-9348. doi: 10.1021/acs.langmuir.7b04369. Epub 2018 Mar 16.

PubMed ID: 29526108

Wang, F. and J. Liu. (2015). A Stable Lipid/TiO Interface with Headgroup-Inversed Phosphocholine and a Comparison with SiO. J Am Chem Soc. 2015 Sep 16;137(36):11736-42. doi: 10.1021/jacs.5b06642. Epub 2015 Aug 28.

PubMed ID: 26302371

Perttu, E.K., A.G. Kohli, and F.C. Szoka Jr. (2012). Inverse-phosphocholine lipids: a remix of a common phospholipid. J Am Chem Soc 134:4485-8.

PubMed ID: 22364493