850312 | DOCPe

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate


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Size SKU Packaging Price
200mg 850312P-200mg 850312P-200mg 1 x 200mg $572.00
25mg 850312P-25mg 850312P-25mg 1 x 25mg $131.00

Chloroform

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25mg 850312C-25mg 850312C-25mg 1 x 25mg 10mg/mL 2.5mL $131.00
200mg 850312C-200mg 850312C-200mg 2 x 100mg 25mg/mL 4mL $572.00
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DOCPe

DOCPe

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate

Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C45H86NO8P
Percent Composition
C 67.55%, H 10.83%, N 1.75%, O16.00%, P3.87%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1360461-58-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
800.140
Exact Mass
799.609
Wang, F. and J. Liu. (2015). A Stable Lipid/TiO Interface with Headgroup-Inversed Phosphocholine and a Comparison with SiO. J Am Chem Soc [PubMed]
This study provides an alternative system for forming stable supported bilayers on TiO2, and represents the first example of interfacing inverse lipids with inorganic surfaces.
Perttu, E.K., A.G. Kohli, and F.C. Szoka Jr. (2012). Inverse-phosphocholine lipids: a remix of a common phospholipid. J Am Chem Soc 134:4485-8. [PubMed]