850311 | DOCP

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl hydrogen phosphate


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Size SKU Packaging Price
100mg 850311P-100mg 850311P-100mg 1 x 100mg $341.00
200mg 850311P-200mg 850311P-200mg 1 x 200mg $572.00

Chloroform

Size SKU Packaging Price
25mg 850311C-25mg 850311C-25mg 1 x 25mg 10mg/mL 2.5mL $131.00
200mg 850311C-200mg 850311C-200mg 2 x 100mg 25mg/mL 4mL $572.00
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DOCP

DOCP

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl hydrogen phosphate

Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase.
Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C43H82NO8P
Percent Composition
C 66.89%, H 10.70%, N 1.81%, O 16.58%, P 4.01%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1360461-57-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
772.087
Exact Mass
771.578

Liu Y, Wang F, Liu J. Headgroup-Inversed Liposomes: Biointerfaces, Supported Bilayers and Applications. Langmuir. 2018 Aug 14;34(32):9337-9348. doi: 10.1021/acs.langmuir.7b04369. Epub 2018 Mar 16.

PubMed ID: 29526108

Liu Y, Liu J. Cu2+-Directed Liposome Membrane Fusion, Positive-Stain Electron Microscopy, and Oxidation. Langmuir. 2018 Jun 12. doi: 10.1021/acs.langmuir.8b00864. [Epub ahead of print]

PubMed ID: 29804456

Wang, F. and J. Liu. (2015). A Stable Lipid/TiO Interface with Headgroup-Inversed Phosphocholine and a Comparison with SiO. J Am Chem Soc [PubMed]

PubMed ID: 26302371

Perttu, E.K., A.G. Kohli, and F.C. Szoka Jr. (2012). Inverse-phosphocholine lipids: a remix of a common phospholipid. J Am Chem Soc 134:4485-8. [PubMed]

PubMed ID: 22364493