850200 | Regadenoson

2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine


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Regadenoson

Regadenoson

2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine

Regadenoson (Lexiscan) is an A2A adenosine receptor agonist used as a coronary vasodilator in pharmacologic stress testing. Recently, it has been demonstrated that regadenoson can temporarily disrupt the integrity of the blood-brain barrier (BBB) by inhibiting P-glycoprotein function.
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C15H18N8O5
Percent Composition
C 46.15%, H 4.65%, N 28.71%, O 20.49%
Purity
>99%
Stability
1 year
Storage Temperature
-20°C
CAS Number
313348-27-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
390.354
Exact Mass
390.140
Synonyms
LexiscanCVT-3146
Cerqueira, M.D. (2004). The future of pharmacologic stress: selective A2A adenosine receptor agonists. Am J Cardiol 94:33D-40D; discussion 40D-42D. [PubMed] Kim, D.G. and M.S. Bynoe. (2016). A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier. J Clin Invest 126:1717-33. [PubMed]