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18:0-20:4 PI(3,4,5)P3 | 850166

1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) (ammonium salt)

850166P

100 μg Powder

1 Ea
$263.00

500 μg Powder

1 Ea
$1052.00

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Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Molecular Formula
C47H98N4O22P4
Percent Composition
C 47.23%, H 8.26%, N 4.69%, O 29.45%, P 10.37%
Purity
>99%
Stability
3 Months
Storage
-20°C
CAS Number
799268-60-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
1195.190
Exact Mass
1194.562
Synonyms
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-[phosphoinositol-3,4,5-trisphosphate] (ammonium salt)
PIP3[3',4',5'](18:0/20:4(5Z,8Z,11Z,14Z))
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Khuong, T.M., R.L. Habets, S. Kuenen, A. Witkowska, J. Kasprowicz, J. Swerts, R. Jahn, G. van den Bogaart, and P. Verstreken. (2013). Synaptic PI(3,4,5)P3 Is Required for Syntaxin1A Clustering and Neurotransmitter Release. Neuron 77:1097-108. [PubMed] Jiang, R.H. and M. Marti. (2012). A PIP Gets the plasmodium protein export pathway going. Cell Host Microbe 11:99-100.[PubMed] Baskaran, S., M.J. Ragusa, E. Boura, and J.H. Hurley. (2012). Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy. Mol Cell. [PubMed] Hammond, G.R., M.J. Fischer, K.E. Anderson, J. Holdich, A. Koteci, T. Balla, and R.F. Irvine. (2012). PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science 337:727-30. [PubMed]