850155 | 18:1 PI(4,5)P2

1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-4',5'-bisphosphate) (ammonium salt)


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100µg 850155P-100µg 850155P-100µg $90.00
500µg 850155P-500µg 850155P-500µg $360.00
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18:1 PI(4,5)P2

18:1 PI(4,5)P2

1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-4',5'-bisphosphate) (ammonium salt)

Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C45H94N3O19P3
Percent Composition
C 50.32%, H 8.82%, N 3.91%, O 28.30%, P 8.65%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
799268-56-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
1074.158
Exact Mass
1073.569
Synonyms
<p>1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-4,5-bisphosphate] (ammonium salt)PIP2[4',5'](18:1(9Z)/18:1(9Z))</p>