850154 | 18:1 PI(3,5)P2

1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',5'-bisphosphate) (ammonium salt)


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100µg 850154P-100ug 850154P-100ug $102.00
500µg 850154P-500ug 850154P-500ug $410.00
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18:1 PI(3,5)P2

18:1 PI(3,5)P2

1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',5'-bisphosphate) (ammonium salt)

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C45H94N3O19P3
Percent Composition
C 50.32%, H 8.82%, N 3.91%, O 28.30%, P 8.65%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
799268-55-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
1074.158
Exact Mass
1073.569
Synonyms
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-3,5-bisphosphate] (ammonium salt)
PIP2[3',5'](18:1(9Z)/18:1(9Z))

Yu CY, Kanehara K. The unfolded protein response modulates a phosphoinositide-binding protein through the IRE1-bZIP60 pathway. Plant Physiol. 2020 Mar 23:pp.01488.2019. doi: 10.1104/pp.19.01488. Epub ahead of print. PMID: 32205450.

PubMed ID: 32205450

Dai A, Yu L, Wang HW. WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. Nat Commun. 2019 Aug 16;10(1):3699. doi: 10.1038/s41467-019-11694-9.

PubMed ID: 31420534

Han BK, Emr SD. The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis. J Biol Chem. 2013 Jul 12;288(28):20633-45. doi: 10.1074/jbc.M113.452813. Epub 2013 Jun 3.

PubMed ID: 23733183

Hammond GR, Fischer MJ, Anderson KE, Holdich J, Koteci A, Balla T, Irvine RF. PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science. 2012 Aug 10;337(6095):727-30. doi: 10.1126/science.1222483. Epub 2012 Jun 21.

PubMed ID: 22722250

Sarmento MJ, Coutinho A, Fedorov A, Prieto M, Fernandes F. Membrane Order Is a Key Regulator of Divalent Cation-Induced Clustering of PI(3,5)P2 and PI(4,5)P2. Langmuir. 2017 Oct 31;33(43):12463-12477. doi: 10.1021/acs.langmuir.7b00666. Epub 2017 Oct 13.

PubMed ID: 28961003