845875 | 18:1 Lyso PC

1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine


Powder

Size SKU Packaging Price
25mg 845875P-25mg 845875P-25mg 1 x 25mg $130.25
200mg 845875P-200mg 845875P-200mg 2 x 100mg $176.00
500mg 845875P-500mg 845875P-500mg 5 x 100mg $255.00

Chloroform

Size SKU Packaging Price
25mg 845875C-25mg 845875C-25mg 1 x 25mg 10mg/mL 2.5mL $130.25
200mg 845875C-200mg 845875C-200mg 2 x 100mg 25mg/mL 4mL $176.00
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18:1 Lyso PC

18:1 Lyso PC

1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C26H52NO7P
Percent Composition
C 59.86%, H 10.05%, N 2.68%, O 21.47%, P 5.94%
Purity
>99% LPC; may contain up to 10% of the 2-LPC isomer
Stability
1 Year
Storage Temperature
-20°C
CAS Number
19420-56-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
521.667
Exact Mass
521.348
Synonyms
<p>1--(9Z-octadecenoyl)-sn-glycero-3-phosphocholinePC(18:1(9Z)/0:0) 110688</p>

Saitta F, Signorelli M, Fessas D. Hierarchy of interactions dictating the thermodynamics of real cell membranes: Following the insulin secretory granules paradigm up to fifteen-components vesicles. Colloids Surf B Biointerfaces. 2019 Dec 9;186:110715. doi: 10.1016/j.colsurfb.2019.110715. [Epub ahead of print]. PMID: 31841777.

PubMed ID: 31841777

Chagas-Lima AC, Pereira MG, Fampa P, Lima MS, Kluck GEG, Atella GC. Bioactive lipids regulate Trypanosoma cruzi development. Parasitol Res. 2019 Sep;118(9):2609-2619. doi: 10.1007/s00436-019-06331-9. Epub 2019 Jul 2.

PubMed ID: 31267245

Engberg O, Scheidt HA, Nyholm TKM, Slotte JP, Huster D. Membrane Localization and Lipid Interactions of Common Lipid-Conjugated Fluorescence Probes. Langmuir. 2019 Sep 10;35(36):11902-11911. doi: 10.1021/acs.langmuir.9b01202. Epub 2019 Aug 29.

PubMed ID: 31424941

Cai H, Cao T, Li N, Fang P, Xu P, Wu X, Zhang B, Xiang D. Quantitative monitoring of a panel of stress-induced biomarkers in human plasma by liquid chromatography-tandem mass spectrometry: an application in a comparative study between depressive patients and healthy subjects. Anal Bioanal Chem. 2019 Jun 14. doi: 10.1007/s00216-019-01956-2. [Epub ahead of print]

PubMed ID: 31201457

Chagovets V, Kononikhin A, Tokoreva A, Bormotov D, Starodubtseva N, Kostyukevich Y, Popov I, Frankevich V, Nikolaev E. Relative quantitation of phosphatidylcholines with interfered masses of protonated and sodiated molecules by tandem and Fourier-transform ion cyclotron resonance mass spectrometry. Eur J Mass Spectrom (Chichester). 2019 Apr;25(2):259-264. doi: 10.1177/1469066718799992.

PubMed ID: 31018698

Levadnyy V, Hasan M, Saha SK, Yamazaki M. Effect of Transmembrane Asymmetric Distribution of Lipids and Peptides on Lipid Bilayers. J Phys Chem B. 2019 Jun 6;123(22):4645-4652. doi: 10.1021/acs.jpcb.9b01562. Epub 2019 May 22.

PubMed ID: 31067409

Sakai N, Bain G, Furuichi K, Iwata Y, Nakamura M, Hara A, Kitajima S, Sagara A, Miyake T, Toyama T, Sato K, Nakagawa S, Shimizu M, Kaneko S, Wada T. The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage. Sci Rep. 2019 May 15;9(1):7414. doi: 10.1038/s41598-019-43576-x.

PubMed ID: 31092842

Dadsena S, Bockelmann S, Mina JGM, Hassan DG, Korneev S, Razzera G, Jahn H, Niekamp P, Müller D, Schneider M, Tafesse FG, Marrink SJ, Melo MN, Holthuis JCM. Ceramides bind VDAC2 to trigger mitochondrial apoptosis. Nat Commun. 2019 Apr 23;10(1):1832. doi: 10.1038/s41467-019-09654-4.

PubMed ID: 31015432

Kommineni N, Mahira S, Domb AJ, Khan W. Cabazitaxel-Loaded Nanocarriers for Cancer Therapy with Reduced Side Effects. Pharmaceutics. 2019 Mar 25;11(3). pii: E141. doi: 10.3390/pharmaceutics11030141.

PubMed ID: 30934535

Kim B, Pena CD, Auguste DT. Targeted Lipid Nanoemulsions Encapsulating Epigenetic Drugs Exhibit Selective Cytotoxicity on CDH1-/FOXM1+ Triple Negative Breast Cancer Cells. Mol Pharm. 2019 Mar 29. doi: 10.1021/acs.molpharmaceut.8b01065. [Epub ahead of print]

PubMed ID: 30883132

Kim B, Pena CD, Auguste DT. Targeted Lipid Nanoemulsions Encapsulating Epigenetic Drugs Exhibit Selective Cytotoxicity on CDH1-/FOXM1+ Triple Negative Breast Cancer Cells. Mol Pharm. 2019 Mar 29. doi: 10.1021/acs.molpharmaceut.8b01065. [Epub ahead of print]

PubMed ID: 30883132

Domínguez Pardo JJ, van Walree CA, Egmond MR, Koorengevel MC, Killian JA. Nanodiscs bounded by styrene-maleic acid allow trans-cis isomerization of enclosed photoswitches of azobenzene labeled lipids. Chem Phys Lipids. 2019 Feb 16;220:1-5. doi: 10.1016/j.chemphyslip.2019.02.002. [Epub ahead of print]

PubMed ID: 30779906

Tams RN, Cassilly CD, Anaokar S, Brewer WT, Dinsmore JT, Chen YL, Patton-Vogt J, Reynolds TB. Overproduction of Phospholipids by the Kennedy Pathway Leads to Hypervirulence in Candida albicans. Front Microbiol. 2019 Feb 7;10:86. doi: 10.3389/fmicb.2019.00086. eCollection 2019.

PubMed ID: 30792701

Qin Q, Wang B, Wang J, Chang M, Xia T, Shi X, Xu G. A comprehensive strategy for studying protein-metabolite interactions by metabolomics and native mass spectrometry. Talanta. 2019 Mar 1;194:63-72. doi: 10.1016/j.talanta.2018.10.010. Epub 2018 Oct 10.

PubMed ID: 30609583

Zhang Q, Xu H, Liu R, Gao P, Yang X, Jin W, Zhang Y, Bi K, Li Q. A Novel Strategy for Targeted Lipidomics Based on LC-Tandem-MS Parameters Prediction, Quantification, and Multiple Statistical Data Mining: Evaluation of Lysophosphatidylcholines as Potential Cancer Biomarkers. Anal Chem. 2019 Mar 5;91(5):3389-3396. doi: 10.1021/acs.analchem.8b04715. Epub 2019 Feb 12.

PubMed ID: 30689358

Stafford, R.E., Fanni, T., Dennis, E.A. (1989) Interfacial properties and critical micelle concentration of lysophospholipids. Biochemistry. 28(12):5113-20.

PubMed ID: 2669968

Bockelmann S, Mina JGM, Korneev S, Hassan DG, Mueller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, Holthuis JCM. A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7. J Lipid Res. 2018 Jan 17. pii: jlr.M082354. doi: 10.1194/jlr.M082354. [Epub ahead of print]

PubMed ID: 29343537