840475 | 18:1 (Δ9-Cis) PG

1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

18:1 (Δ9-Cis) PG


Size SKU Packaging Price
25mg 840475P-25mg 840475P-25mg 1 x 25mg $94.25
200mg 840475P-200mg 840475P-200mg 2 x 100mg $276.00
500mg 840475P-500mg 840475P-500mg 5 x 100mg $465.00
1g 840475P-1g 840475P-1g 1 x 1g $711.02
Request Bulk Pricing


Size SKU Packaging Price
25mg 840475C-25mg 840475C-25mg 1 x 25mg 10mg/mL 2.5mL $94.25 94.25
200mg 840475C-200mg 840475C-200mg 2 x 100mg 25mg/mL 4mL $276.00 276
500mg 840475C-500mg 840475C-500mg 5 x 100mg 25mg/mL 4mL $465.00 465
Request Bulk Pricing


18:1 (Δ9-Cis) PG

1,2-dioleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

Light Sensitive
Molecular Formula
Percent Composition
C 63.29%, H 9.86%, Na 2.88%, O 20.07%, P 3.89%
1 Year
Storage Temperature
CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
Exact Mass
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)
Transition Temp
Solubility in Different Solvents
Insoluble in DMSO, soluble in ethanol and Chloroform:Methanol:Water (65:25:4) at 5mg/mL

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Halder A, Sannigrahi A, De N, Chattopadhyay K, Karmakar S. Kinetoplastid Membrane Protein-11 Induces Pores in Anionic Phospholipid Membranes: Effect of Cholesterol. Langmuir. 2020 Mar 23. doi: 10.1021/acs.langmuir.9b03816. Epub ahead of print. PMID: 32160748.

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Yang K, Mesquita B, Horvatovich P, Salvati A. Tuning liposome composition to modulate corona formation in human serum and cellular uptake. Acta Biomater. 2020 Apr 1;106:314-327. doi: 10.1016/j.actbio.2020.02.018. Epub 2020 Feb 17. PMID: 32081780.

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Karal MAS, Ahmed M, Levadny V, Belaya M, Ahamed MK, Rahman M, Shakil MM. Electrostatic interaction effects on the size distribution of self-assembled giant unilamellar vesicles. Phys Rev E. 2020 Jan;101(1-1):012404. doi: 10.1103/PhysRevE.101.012404. PMID: 32069606.

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Israeli R, Kolusheva S, Hadad U, Jelinek R. Imaging Flow Cytometry Illuminates New Dimensions of Amyloid Peptide-Membrane Interactions. Biophys J. 2020 Jan 28:S0006-3495(20)30064-3. doi: 10.1016/j.bpj.2020.01.018. Epub ahead of print. PMID: 32053776.

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Olatunji S, Yu X, Bailey J, Huang CY, Zapotoczna M, Bowen K, Remškar M, Müller R, Scanlan EM, Geoghegan JA, Olieric V, Caffrey M. Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin. Nat Commun. 2020 Jan 9;11(1):140. doi: 10.1038/s41467-019-13724-y. PMID: 31919415; PMCID: PMC6952399.

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Benne N, Leboux RJT, Glandrup M, van Duijn J, Lozano Vigario F, Neustrup MA, Romeijn S, Galli F, Kuiper J, Jiskoot W, Slütter B. Atomic force microscopy measurements of anionic liposomes reveal the effect of liposomal rigidity on antigen-specific regulatory T cell responses. J Control Release. 2019 Dec 5;318:246-255. doi: 10.1016/j.jconrel.2019.12.003. [Epub ahead of print]. PMID: 31812539.

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Borro BC, Toussaint MS, Bucciarelli S, Malmsten M. Effects of charge contrast and composition on microgel formation and interactions with bacteria-mimicking liposomes. Biochim Biophys Acta Gen Subj. 2019 Nov 15:129485. doi: 10.1016/j.bbagen.2019.129485. [Epub ahead of print]

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Almeida AM Jr, Oliveira ON Jr, Aoki PHB. Role of Toluidine Blue-O Binding Mechanism for Photooxidation in Bioinspired Bacterial Membranes. Langmuir. 2019 Dec 24;35(51):16745-16751. doi: 10.1021/acs.langmuir.9b03045. Epub 2019 Dec 9.

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Bellefroid C, Lechanteur A, Evrard B, Mottet D, Debacq-Chainiaux F, Piel G. In vitro skin penetration enhancement techniques: A combined approach of ethosomes and microneedles. Int J Pharm. 2019 Dec 15;572:118793. doi: 10.1016/j.ijpharm.2019.118793. Epub 2019 Nov 9.

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Speth JM, Penke LR, Bazzill JD, Park KS, de Rubio RG, Schneider DJ, Ouchi H, Moon JJ, Keshamouni VG, Zemans RL, Lama VN, Arenberg DA, Peters-Golden M. Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics. JCI Insight. 2019 Oct 17;4(20). pii: 131340. doi: 10.1172/jci.insight.131340.

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Karal MAS, Ahamed MK, Rahman M, Ahmed M, Shakil MM, Siddique-E-Rabbani K. Effects of electrically-induced constant tension on giant unilamellar vesicles using irreversible electroporation. Eur Biophys J. 2019 Dec;48(8):731-741. doi: 10.1007/s00249-019-01398-9. Epub 2019 Sep 24.

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Takechi-Haraya Y, Goda Y, Izutsu K, Sakai-Kato K. Improved Atomic Force Microscopy Stiffness Measurements of Nanoscale Liposomes by Cantilever Tip Shape Evaluation. Anal Chem. 2019 Aug 20;91(16):10432-10440. doi: 10.1021/acs.analchem.9b00250. Epub 2019 Aug 7.

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Giulimondi F, Digiacomo L, Pozzi D, Palchetti S, Vulpis E, Capriotti AL, Chiozzi RZ, Laganà A, Amenitsch H, Masuelli L, Mahmoudi M, Screpanti I, Zingoni A, Caracciolo G. Interplay of protein corona and immune cells controls blood residency of liposomes. Nat Commun. 2019 Aug 15;10(1):3686. doi: 10.1038/s41467-019-11642-7.

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Ray S, Vazquez Reyes S, Xiao C, Sun J. Effects of membrane lipid composition on Mycobacterium tuberculosis EsxA membrane insertion: A dual play of fluidity and charge. Tuberculosis (Edinb). 2019 Jul 30;118:101854. doi: 10.1016/j.tube.2019.07.005. [Epub ahead of print]

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Dhindwal S, Feng S, Khayat R. The Arginines in the N-Terminus of the Porcine Circovirus 2 Virus-like Particles Are Responsible for Disrupting the Membranes at Neutral and Acidic pH. J Mol Biol. 2019 Jun 4. pii: S0022-2836(19)30334-1. doi: 10.1016/j.jmb.2019.05.044. [Epub ahead of print]

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Karal MAS, Rahman M, Ahamed MK, Shibly SUA, Ahmed M, Shakil MM. Low cost non-electromechanical technique for the purification of giant unilamellar vesicles. Eur Biophys J. 2019 May;48(4):349-359. doi: 10.1007/s00249-019-01363-6. Epub 2019 Mar 27.

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Takuma Makihara, Steven M. E. Demers, Louis E. D. Cole, Aobo Zhang and Jason H. Hafner. Thermophoresis of gold nanorods from surface enhanced Raman scattering and real-time Rayleigh scattering in solution. Anal. Methods, 2019,11, 2482-2488. doi: 10.1039/C9AY00104

Dadhich R, Singh A, Menon AP, Mishra M, Athul CD, Kapoor S. Biophysical characterization of mycobacterial model membranes and their interaction with rifabutin: Towards lipid-guided drug screening in tuberculosis. Biochim Biophys Acta Biomembr. 2019 Jun 1;1861(6):1213-1227. doi: 10.1016/j.bbamem.2019.04.004. Epub 2019 Apr 17.

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Fan X, Xu W, Han J, Jiang X, Wink M, Wu G. Antimicrobial peptide hybrid fluorescent protein based sensor array discriminate ten most frequent clinic isolates. Biochim Biophys Acta Gen Subj. 2019 Jun;1863(6):1158-1166. doi: 10.1016/j.bbagen.2019.04.010. Epub 2019 Apr 12.

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Izzo L, Matrella S, Mella M, Benvenuto G, Vigliotta G. Escherichia coli as a Model for the Description of the Antimicrobial Mechanism of a Cationic Polymer Surface: Cellular Target and Bacterial Contrast Response. ACS Appl Mater Interfaces. 2019 May 1;11(17):15332-15343. doi: 10.1021/acsami.9b02903. Epub 2019 Apr 19.

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Malekkhaiat Häffner S, Nyström L, Browning KL, Mörck Nielsen H, Strömstedt AA, van der Plas MJA, Schmidtchen A, Malmsten M. Interaction of Laponite with Membrane Components-Consequences for Bacterial Aggregation and Infection Confinement. ACS Appl Mater Interfaces. 2019 May 1;11(17):15389-15400. doi: 10.1021/acsami.9b03527. Epub 2019 Apr 17.

PubMed ID: 30951282

Tetsuya Ohta, Risato Yamada, Satoshi Fujita, Taketoshi Takahata, Kohei Shiba, Sachiko Machida, Shin-ichi Tate. DOPG small unilamellar vesicles function as nano-carriers targeting the clustered lectin-like oxidized LDL receptor (LOX-1) on the cell surface. Journal of Drug Delivery Science and Technology. 2019 June;51:327-336. doi: 10.1016/j.jddst.2019.03.014

Maqbool F, Moyle PM, Thurecht KJ, Falconer JR. Dispersibility of phospholipids and their optimization for the efficient production of liposomes using supercritical fluid technology. Int J Pharm. 2019 Mar 30;563:174-183. doi: 10.1016/j.ijpharm.2019.03.053. [Epub ahead of print]

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Shih YL, Huang LT, Tu YM, Lee BF, Bau YC, Hong CY, Lee HL, Shih YP, Hsu MF, Lu ZX, Chen JS, Chao L. Active Transport of Membrane Components by Self-Organization of the Min Proteins. Biophys J. 2019 Mar 23. pii: S0006-3495(19)30197-3. doi: 10.1016/j.bpj.2019.03.011. [Epub ahead of print]

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Jacobs D, Hoogerheide DP, Rovini A, Jiang Z, Lee JC, Rostovtseva TK, Bezrukov SM. Probing Membrane Association of α-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding Pattern. Sci Rep. 2019 Mar 14;9(1):4580. doi: 10.1038/s41598-019-40979-8.

PubMed ID: 30872688

Ben-Zichri S, Kolusheva S, Danilenko M, Ossikbayeva S, Stabbert WJ, Poggio JL, Stein DE, Orynbayeva Z, Jelinek R. Cardiolipin mediates curcumin interactions with mitochondrial membranes. Biochim Biophys Acta Biomembr. 2019 Jan;1861(1):75-82. doi: 10.1016/j.bbamem.2018.10.016. Epub 2018 Oct 31.

PubMed ID: 30389425

Luque-Caballero G, Maldonado-Valderrama J, Quesada-Pérez M, Martín-Molina A. Interaction of DNA with likely-charged lipid monolayers: An experimental study. Colloids Surf B Biointerfaces. 2019 Mar 1;178:170-176. doi: 10.1016/j.colsurfb.2019.02.058. [Epub ahead of print]

PubMed ID: 30856586

Barbosa SC, Nobre TM, Volpati D, Cilli EM, Correa DS, Oliveira ON Jr. The cyclic peptide labaditin does not alter the outer membrane integrity of Salmonella enterica serovar Typhimurium. Sci Rep. 2019 Feb 13;9(1):1993. doi: 10.1038/s41598-019-38551-5.

PubMed ID: 30760803

Gao S, Wan Y, Li W, Huang C. Visualized Networking of Co-Regulated Lipids in Human Blood Based on High-Throughput Screening Data: Implications for Exposure Assessment. Environ Sci Technol. 2019 Mar 5;53(5):2862-2872. doi: 10.1021/acs.est.8b06289. Epub 2019 Feb 21.

PubMed ID: 30739451

Palchetti S, Caputo D, Digiacomo L, Capriotti AL, Coppola R, Pozzi D, Caracciolo G. Protein Corona Fingerprints of Liposomes: New Opportunities for Targeted Drug Delivery and Early Detection in Pancreatic Cancer. Pharmaceutics. 2019 Jan 15;11(1). pii: E31. doi: 10.3390/pharmaceutics11010031.

PubMed ID: 30650541

Dedic J, Rocha S, Okur HI, Wittung-Stafshede P, Roke S. Membrane-Protein-Hydration Interaction of α-Synuclein with Anionic Vesicles Probed via Angle-Resolved Second-Harmonic Scattering. J Phys Chem B. 2019 Feb 7;123(5):1044-1049. doi: 10.1021/acs.jpcb.8b11096. Epub 2019 Jan 24.

PubMed ID: 30625272

Yanru Xin, Huazhi Zhang, Qigang Hu, Sidan Tian, Chenhui Wang, Liang Luo, and Fanling Meng. Oligotyrosines Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in a Tyrosine-Number-Dependent Manner. ACS Biomater. Sci. Eng. 2019, 5, 2, 1092-1099. doi: 10.1021/acsbiomaterials.8b01384

Garle AL, Budhlall BM. PEG Bottle Brush Copolymers as Antimicrobial Mimics: Role of Entropic Templating in Membrane Lysis. Langmuir. 2019 Mar 5;35(9):3372-3382. doi: 10.1021/acs.langmuir.8b00756. Epub 2019 Feb 18.

PubMed ID: 30646685

Konate K, Dussot M, Aldrian G, Vaissière A, Viguier V, Ferreiro Neira I, Couillaud F, Vivès E, Boisguerin P, Deshayes S. Peptide-based nanoparticles to rapidly and efficiently "Wrap'n Roll" siRNA into cells. Bioconjug Chem. 2018 Dec 26. doi: 10.1021/acs.bioconjchem.8b00776. [Epub ahead of print]

PubMed ID: 30586303

Ewins E, Lira RB, Zhang W, Yuan J, Antonietti M, Robinson T, Dimova R. Poly(Ionic Liquid) Nanoparticles Selectively Disrupt Biomembranes. Adv Sci (Weinh). 2018 Dec 17;6(4):1801602. doi: 10.1002/advs.201801602. eCollection 2019 Feb 2019

PubMed ID: 30828532

Binte Mustafiz SS, Uyama T, Hussain Z, Kawai K, Tsuboi K, Araki N, Ueda N. The role of intracellular anionic phospholipids in the production of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2ε. J Biochem. 2018 Dec 4. doi: 10.1093/jb/mvy104. [Epub ahead of print]

PubMed ID: 30517655

Yanru Xin, Huazhi Zhang, Qigang Hu, Sidan Tian, Chenhui Wang, Liang Luo, and Fanling Meng. Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in a Tyrosine-Number-Dependent Manner. ACS Biomaterials Science & Engineering 2019 5 (2), 1092-1099. DOI: 10.1021/acsbiomaterials.8b01384

Di Domenico M, Pozzi D, Palchetti S, Digiacomo L, Iorio R, Astarita C, Fiorelli A, Pierdiluca M, Santini M, Barbarino M, Giordano A, Di Carlo A, Frati L, Mahmoudi M, Caracciolo G. Nanoparticle-biomolecular corona: A new approach for the early detection of non-small-cell lung cancer. J Cell Physiol. 2019 Jun;234(6):9378-9386. doi: 10.1002/jcp.27622. Epub 2018 Dec 5.

PubMed ID: 3050022

Gao S, Wan Y, Li W, Huang C. Visualized Networking of Co-Regulated Lipids in Human Blood Based on High-Throughput Screening Data: Implications for Exposure Assessment. Environ Sci Technol. 2019 Feb 21. doi: 10.1021/acs.est.8b06289. [Epub ahead of print

PubMed ID: 30739451

Zhang X, Pandiakumar AK, Hamers RJ, Murphy CJ. Quantification of Lipid Corona Formation on Colloidal Nanoparticles from Lipid Vesicles. Anal Chem. 2018 Dec 18;90(24):14387-14394. doi: 10.1021/acs.analchem.8b03911. Epub 2018 Nov 20.

PubMed ID: 30427176

Feng Y, Chen B, Yu Q, Li L. Identification of Double Bond Position Isomers in Unsaturated Lipids by m-CPBA Epoxidation and Mass Spectrometry Fragmentation. Anal Chem. 2019 Jan 4. doi: 10.1021/acs.analchem.8b04905. [Epub ahead of print]

PubMed ID: 30608661

Zhang X, Barraza KM, Upton KT, Beauchamp JL. Subtle Changes in Lipid Environment Have Profound Effects on Membrane Oxidation Chemistry. J Am Chem Soc. 2018 Nov 21. doi: 10.1021/jacs.8b08610. [Epub ahead of print]

PubMed ID: 30461271

Zhang X, Pandiakumar AK, Hamers RJ, Murphy CJ. Quantification of Lipid Corona Formation on Colloidal Nanoparticles from Lipid Vesicles. Anal Chem. 2018 Nov 20. doi: 10.1021/acs.analchem.8b03911. [Epub ahead of print]

PubMed ID: 30427176

Amadei F, Fröhlich B, Stremmel W, Tanaka M. Non-Classical Interactions of Phosphatidylcholine with Mucin Protect Intestinal Surfaces: A Microinterferometry Study. Langmuir. 2018 Oct 25. doi: 10.1021/acs.langmuir.8b03035. [Epub ahead of print]

PubMed ID: 30359036

Eric H. Hill, Jingang Li, Linhan Lin, Yaoran Liu, and Yuebing Zheng. Opto-Thermophoretic Attraction, Trapping, and Dynamic Manipulation of Lipid Vesicles. Langmuir, Just Accepted Manuscript. DOI: 10.1021/acs.langmuir.8b01979. Publication Date (Web): October 11, 2018

PubMed ID: 30350700

Patrick M. Arnott, Himanshu Joshi, Aleksei Aksimentiev, and Stefan Howorka. Dynamic Interactions between Lipid-Tethered DNA and Phospholipid Membranes. Langmuir, Article ASAP DOI: 10.1021/acs.langmuir.8b02271 Publication Date (Web): October 10, 2018

Bao H, Das D, Courtney NA, Jiang Y, Briguglio JS, Lou X, Roston D, Cui Q, Chanda B, Chapman ER. Dynamics and number of trans-SNARE complexes determine nascent fusion pore properties. Nature. 2018 Feb 8;554(7691):260-263. doi: 10.1038/nature25481. Epub 2018 Jan 31.

PubMed ID: 29420480

Lee MT, Yang PY, Charron NE, Hsieh MH, Chang YY, Huang HW. Comparison of the Effects of Daptomycin on Bacterial and Model Membranes. Biochemistry. 2018 Sep 7. doi: 10.1021/acs.biochem.8b00818. [Epub ahead of print]

PubMed ID: 30153001

Takechi-Haraya Y, Goda Y, Sakai-Kato K. Atomic Force Microscopy Study on the Stiffness of Nanosized Liposomes Containing Charged Lipids. Langmuir. 2018 Jun 18. doi: 10.1021/acs.langmuir.8b01121. [Epub ahead of print]

PubMed ID: 29869883

Steer D, Leung SSW, Meiselman H, Topgaard D, Leal C. Structure of Lung-Mimetic Multilamellar Bodies with Lipid Compositions Relevant in Pneumonia. Langmuir. 2018 Jun 14. doi: 10.1021/acs.langmuir.8b01359. [Epub ahead of print]

PubMed ID: 29847137

Liu Y, Liu J. Cu2+-Directed Liposome Membrane Fusion, Positive-Stain Electron Microscopy, and Oxidation. Langmuir. 2018 Jun 12. doi: 10.1021/acs.langmuir.8b00864. [Epub ahead of print]

PubMed ID: 29804456

Beltramo PJ, Scheidegger L, Vermant J. Toward Realistic Large-Area Cell Membrane Mimics: Excluding Oil, Controlling Composition, and Including Ion Channels. Langmuir. 2018 May 14. doi: 10.1021/acs.langmuir.8b00837.

PubMed ID: 29715042

Ma L, Li Y, Ma J, Hu S, Li M. Watching Three-Dimensional Movements of Single Membrane Proteins in Lipid Bilayers. Biochemistry. 2018 Apr 12. doi: 10.1021/acs.biochem.8b00253

PubMed ID: 29619828

Yu Q, Sun J, Huang S, Chang H, Bai Q, Chen YX, Liang D. Inward Budding and Endocytosis of Membranes Regulated by de Novo Designed Peptides. Langmuir. 2018 May 16. doi: 10.1021/acs.langmuir.8b00882. [Epub ahead of print]

PubMed ID: 29733597

Chavarha, M., R.W. Loney, S.B. Rananavare, and S.B. Hall. (2013). An anionic phospholipid enables the hydrophobic surfactant proteins to alter spontaneous curvature. Biophys J 104:594-603.

PubMed ID: 23442910

Effects of Mechanical Properties of Lipid Bilayers on the Entry of Cell-Penetrating Peptides into Single Vesicles, Md. Zahidul Islam†, Sabrina Sharmin†, Victor Levadnyy†‡, Sayed Ul Alam Shibly†, and Masahito Yamazaki*†§∥ †Integrated Bioscience Section, Graduate School of Science and Technology, §Nanomaterials Research Division, Research Institute of Electronics, and ∥Department of Physics, Graduate School of Science, Shizuoka University, Shizuoka 422-8529, Japan ‡ Theoretical Problem Center of Physico-Chemical Pharmacology, Russian Academy of Sciences, Kosugina, 4, 117977, Moscow, Russia, Langmuir, Article ASAP DOI: 10.1021/acs.langmuir.6b03111

PubMed ID: 28166411

Bockelmann S, Mina JGM, Korneev S, Hassan DG, Mueller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, Holthuis JCM. A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7. J Lipid Res. 2018 Jan 17. pii: jlr.M082354. doi: 10.1194/jlr.M082354.

PubMed ID: 29343537
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