840445 | 14:0 PG

1,2-dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)


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14:0 PG

14:0 PG

1,2-dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C34H66O10PNa
Percent Composition
C 59.28%, H 9.66%, Na 3.34%, O 23.23%, P 4.50%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
200880-40-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
688.845
Exact Mass
688.429
Synonyms
<p>1,2-ditetradecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)</p>
<p>DMPG</p>
<p>PG(14:0/14:0)&nbsp;</p>
<p>110648</p>

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Suchodolski J, Muraszko J, Korba A, Bernat P, Krasowska A. Lipid composition and cell surface hydrophobicity of Candida albicans influence the efficacy of fluconazole-gentamicin treatment. Yeast. 2020 Jan;37(1):117-129. doi: 10.1002/yea.3455. Epub 2020 Jan 10. PMID: 31826306.

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PubMed ID: 31847173

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Verma A, Schmidt BA, Elizaldi SR, Nguyen NK, Walter KA, Beck Z, Trinh HV, Dinsarapu AR, Lakshmanappa YS, Rane NN, Matyas GR, Rao M, Shen X, Tomaras GD, LaBranche CC, Reimann KA, Foehl DH, Gach JS, Forthal DN, Kozlowski PA, Amara RR, Iyer SS. Impact of Th1 CD4 TFH skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. J Virol. 2019 Dec 11;JVI.01737-19. doi: 10.1128/JVI.01737-19. [Epub ahead of print]. PMID: 31827000.

PubMed ID: 31827000

Khairalla B, Juhaniewicz-Debinska J, Sek S, Brand I. The shape of lipid molecules affects potential-driven molecular-scale rearrangements in model cell membranes on electrodes. Bioelectrochemistry. 2019 Dec 14;132:107443. doi: 10.1016/j.bioelechem.2019.107443. [Epub ahead of print]. PMID: 31869700.

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Wang L, Wang Z, Qin Y, Liang W. Delivered antigen peptides to resident CD8α+ DCs in lymph node by micelle-based vaccine augment antigen-specific CD8+ effector T cell response. Eur J Pharm Biopharm. 2020 Feb;147:76-86. doi: 10.1016/j.ejpb.2019.12.013. Epub 2019 Dec 28. PMID: 31887349.

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Pond MP, Eells R, Treece BW, Heinrich F, Lösche M, Roux B. Membrane Anchoring of Hck Kinase via the Intrinsically Disordered SH4-U and Length Scale Associated with Subcellular Localization. J Mol Biol. 2019 Dec 23;S0022-2836(19)30721-1. doi: 10.1016/j.jmb.2019.11.024. [Epub ahead of print]. PMID: 31877324.

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Momtazi-Borojeni AA, Jaafari MR, Badiee A, Banach M, Sahebkar A. Therapeutic effect of nanoliposomal PCSK9 vaccine in a mouse model of atherosclerosis. BMC Med. 2019;17(1):223. Published 2019 Dec 10. doi:10.1186/s12916-019-1457-8

PubMed ID: 31818299

Pinheiro M, Amenitsch H, Reis S. Antituberculosis Drug Interactions with Membranes: A Biophysical Approach Applied to Bedaquiline. Membranes (Basel). 2019 Oct 30;9(11). pii: E141. doi: 10.3390/membranes9110141.

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Gill EL, Koelmel JP, Meke L, Yost RA, Garrett TJ, Okun MS, Flores C, Vedam-Mai V. Ultrahigh-Performance Liquid Chromatography-High-Resolution Mass Spectrometry Metabolomics and Lipidomics Study of Stool from Transgenic Parkinson's Disease Mice Following Immunotherapy. J Proteome Res. 2020 Jan 3;19(1):424-431. doi: 10.1021/acs.jproteome.9b00605. Epub 2019 Nov 22.

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Medina Amado C, Minahk CJ, Cilli E, Oliveira RG, Dupuy FG. Bacteriocin enterocin CRL35 is a modular peptide that induces non-bilayer states in bacterial model membranes. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183135. doi: 10.1016/j.bbamem.2019.183135. Epub 2019 Nov 15.

PubMed ID: 31738901

Malik E, Phoenix DA, Badiani K, Snape TJ, Harris F, Singh J, Morton LHG, Dennison SR. Biophysical studies on the antimicrobial activity of linearized esculentin 2EM. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183141. doi: 10.1016/j.bbamem.2019.183141. Epub 2019 Nov 29.

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Antonelli M, Benedetti B, Cavaliere C, Cerrato A, Montone CM, Piovesana S, Lagana A, Capriotti AL. Phospholipidome of extra virgin olive oil: Development of a solid phase extraction protocol followed by liquid chromatography-high resolution mass spectrometry for its software-assisted identification. Food Chem. 2020 Apr 25;310:125860. doi: 10.1016/j.foodchem.2019.125860. Epub 2019 Nov 8.

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Chamberlain CA, Hatch M, Garrett TJ. Metabolomic profiling of oxalate-degrading probiotic Lactobacillus acidophilus and Lactobacillus gasseri. PLoS One. 2019 Sep 23;14(9):e0222393. doi: 10.1371/journal.pone.0222393. eCollection 2019.

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Vander Zanden CM, Wampler L, Bowers I, Watkins EB, Majewski J, Chi EY. Fibrillar and Nonfibrillar Amyloid Beta Structures Drive Two Modes of Membrane-Mediated Toxicity. Langmuir. 2019 Sep 26. doi: 10.1021/acs.langmuir.9b02484. [Epub ahead of print]

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Lopes D, Melo T, Meneses J, Abreu MH, Pereira R, Domingues P, Lillebø AI, Calado R5, Domingues MR. A New Look for the Red Macroalga Palmaria palmata: A Seafood with Polar Lipids Rich in EPA and with Antioxidant Properties. Mar Drugs. 2019 Sep 13;17(9). pii: E533. doi: 10.3390/md17090533.

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Faria MJ, Machado R, Ribeiro A, Gonçalves H, Real Oliveira MECD, Viseu T, das Neves J, Lúcio M. Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention. Pharmaceutics. 2019 Sep 18;11(9). pii: E485. doi: 10.3390/pharmaceutics11090485.

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Wang X, Zhang H, Song Y, Cong P, Li Z, Xu J, Xue C. Comparative Lipid Profile Analysis of Four Fish Species by Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry. J Agric Food Chem. 2019 Aug 21;67(33):9423-9431. doi: 10.1021/acs.jafc.9b03303. Epub 2019 Aug 8.

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Myers WA, Rico JE, Davis AN, Fontoura ABP, Dineen MJ, Tate BN, McFadden JW. Effects of abomasal infusions of fatty acids and one-carbon donors on hepatic ceramide and phosphatidylcholine in lactating Holstein dairy cows. J Dairy Sci. 2019 Aug;102(8):7087-7101. doi: 10.3168/jds.2018-16200. Epub 2019 Jun 6.

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F. Varenne, J.-B.Coty, J.Botton, F.-X. Legrand, H. Hillaireau, G. Barratt, C. Vauthier. Evaluation of zeta potential of nanomaterials by electrophoretic light scattering: Fast field reversal versus Slow field reversal modes. Talanta. 1 December 2019;205:120062. doi: 10.1016/j.talanta.2019.06.062.


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Dalchand N, Doğangün M, Ohno PE, Ma E, Martinson ABF, Geiger FM. Perturbation of Hydrogen Bonding Networks Over Supported Lipid Bilayers by Poly (allylamine hydrochloride). J Phys Chem B. 2019 Apr 23. doi: 10.1021/acs.jpcb.9b02392. [Epub ahead of print]

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Wójcik A, Bieniasz A, Wydro P, Broniatowski M. The effect of chlorination degree and substitution pattern on the interactions of polychlorinated biphenyls with model bacterial membranes. Biochim Biophys Acta Biomembr. 2019 Mar 16;1861(6):1057-1068. doi: 10.1016/j.bbamem.2019.03.009. [Epub ahead of print]

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Martial B, Lefèvre T, Buffeteau T, Auger M. Vibrational Circular Dichroism Reveals Supramolecular Chirality Inversion of α-Synuclein Peptide Assemblies upon Interactions with Anionic Membranes. ACS Nano. 2019 Mar 26;13(3):3232-3242. doi: 10.1021/acsnano.8b08932. Epub 2019 Mar 1.

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Raasakka A, Jones NC, Hoffmann SV, Kursula P. Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero. Biochem Biophys Res Commun. 2019 Mar 26;511(1):7-12. doi: 10.1016/j.bbrc.2019.02.025. Epub 2019 Feb 10.

PubMed ID: 30755303

Shue Li, Hongbo Yu, Yuxin Liu, Xiaoyu Zhang, Fuying Ma. The lipid strategies in Cunninghamella echinulata for an allostatic response to temperature changes. Process Biochemistry. 2019 January;76:85-94. doi: 10.1016/j.procbio.2018.11.005


Kao YM, Cheng CH, Syue ML, Huang HY, Chen IC, Yu TY, Chu LK. Photochemistry of Bacteriorhodopsin with Various Oligomeric Statuses in Controlled Membrane Mimicking Environments: A Spectroscopic Study from Femtoseconds to Milliseconds. J Phys Chem B. 2019 Mar 7;123(9):2032-2039. doi: 10.1021/acs.jpcb.9b01224. Epub 2019 Feb 21.

PubMed ID: 30742764

Ben-Zichri S, Kolusheva S, Danilenko M, Ossikbayeva S, Stabbert WJ, Poggio JL, Stein DE, Orynbayeva Z, Jelinek R. Cardiolipin mediates curcumin interactions with mitochondrial membranes. Biochim Biophys Acta Biomembr. 2019 Jan;1861(1):75-82. doi: 10.1016/j.bbamem.2018.10.016. Epub 2018 Oct 31.

PubMed ID: 30389425

Perez-Lopez MI, Mendez-Reina R, Trier S, Herrfurth C, Feussner I, Bernal A, Forero-Shelton M, Leidy C. Variations in carotenoid content and acyl chain composition in exponential, stationary and biofilm states of Staphylococcus aureus, and their influence on membrane biophysical properties. Biochim Biophys Acta Biomembr. 2019 May 1;1861(5):978-987. doi: 10.1016/j.bbamem.2019.02.001. Epub 2019 Feb 13.

PubMed ID: 30771288

Bourgeois C, Gomaa AI, Lefèvre T, Cansell M, Subirade M. Interaction of oil bodies proteins with phospholipid bilayers: A molecular level elucidation as revealed by infrared spectroscopy. Int J Biol Macromol. 2019 Feb 1;122:873-881. doi: 10.1016/j.ijbiomac.2018.10.211. Epub 2018 Nov 1.

PubMed ID: 30391431

Tang TC, Kienlen-Campard P, Hu Y, Perrin F, Opsomer R, Octave JN, Constantinescu SN, Smith SO. Influence of the familial Alzheimer's disease-associated T43I mutation on the transmembrane structure and γ-secretase processing of the C99 peptide. J Biol Chem. 2019 Feb 12. pii: jbc.RA118.006061. doi: 10.1074/jbc.RA118.006061. [Epub ahead of print]

PubMed ID: 30755484

Inada M, Kinoshita M, Sumino A, Oiki S, Matsumori N. A concise method for quantitative analysis of interactions between lipids and membrane proteins. Anal Chim Acta. 2019 Jun 20;1059:103-112. doi: 10.1016/j.aca.2019.01.042. Epub 2019 Feb 1.

PubMed ID: 30876624

Kyle JE, Burnum-Johnson KE, Wendler JP, Eisfeld AJ, Halfmann PJ, Watanabe T, Sahr F, Smith RD, Kawaoka Y, Waters KM, Metz TO. Plasma lipidome reveals critical illness and recovery from human Ebola virus disease. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3919-3928. doi: 10.1073/pnas.1815356116. Epub 2019 Feb 11.

PubMed ID: 30808769

Kumar CS, Singh BP, Alim S, Swamy MJ. Factors Influencing the Chaperone-Like Activity of Major Proteins of Mammalian Seminal Plasma, Equine HSP-1/2 and Bovine PDC-109: Effect of Membrane Binding, pH and Ionic Strength. Adv Exp Med Biol. 2018;1112:53-68. doi: 10.1007/978-981-13-3065-0_5.

PubMed ID: 30637690

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Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol