Products

Brain PI(4,5)P2 | 840046

L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt)

840046X

CHCl3/MeOH/H2O (20:9:1)

1 mg
$275.00
5 mg
$1180.00
10 mg
$2060.00
25 mg
$4590.00

840046P

Powder

1 mg
$290.00
5 mg
$1195.00
10 mg
$2075.00
25 mg
$4605.00

All Prices in US Dollars
Custom packaging is calculated at $4.00 per aliquot and will be charged at the time of shipping.

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  • Product
  • Data
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  • Fatty Acid Distribution
Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.
Purity
>99%
Stability
6 Months
Storage
-20°C
CAS Number
383907-42-4
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
1096.385 (average based on fatty acid distribution in product)
Synonyms
Brain PI(4,5)P2
Download
Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
This Natural Lipid is a mixture and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.