In observance of Thanksgiving Avanti will close at 2 PM Wednesday, November 22nd and will re-open on Monday, November 27th at 8 AM.

Products

Brain PI(4,5)P2 | 840046

L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt)

840046X

CHCl3/MeOH/H2O (20:9:1)

840046X-
1mg
$305.00
840046X-
5mg
$1255.00
840046X-
10mg
$2179.00
840046X-
25mg
$4835.00

840046P

Powder

840046P-
1mg
$305.00
840046P-
5mg
$1255.00
840046P-
10mg
$2179.00
840046P-
25mg
$4835.00

All Prices in US Dollars
Quantity discounts may be available at the 5 and 10 count level.
Contact customer service for a quote.
Add your chosen unit to the shopping cart and adjust the quantity to see the discount.


To purchase larger quantities of this product please contact our Customer Service Department

  • Product
  • Data
  • Downloads
  • Fatty Acid Distribution
Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.
Purity
>99%
Stability
3 Months
Storage
-20°C
CAS Number
383907-42-4
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
1096.385 (average based on fatty acid distribution in product)
Synonyms
Brain PI(4,5)P2
Download
Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
This Natural Lipid is a mixture and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.