840035 | 18:1 PS (DOPS)

1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt)


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Size SKU Packaging Price
10mg 840035P-10mg 840035P-10mg 1 x 10mg $83.00
25mg 840035P-25mg 840035P-25mg 1 x 25mg $116.00
200mg 840035P-200mg 840035P-200mg 2 x 100mg $646.00
500mg 840035P-500mg 840035P-500mg 5 x 100mg $1,110.00

Chloroform

Size SKU Packaging Price
10mg 840035C-10mg 840035C-10mg 1 x 10mg 10mg/mL 1mL $83.00
25mg 840035C-25mg 840035C-25mg 1 x 25mg 10mg/mL 2.5mL $116.00
200mg 840035C-200mg 840035C-200mg 2 x 100mg 25mg/mL 4mL $646.00
500mg 840035C-500mg 840035C-500mg 5 x 100mg 25mg/mL 4mL $1,110.00
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18:1 PS (DOPS)

18:1 PS (DOPS)

1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C42H77NO10PNa
Percent Composition
C 62.28%, H 9.58%, N 1.73%, Na 2.84%, O 19.75%, P 3.82%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
90693-88-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
810.025
Exact Mass
809.518
Synonyms

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt)

DOPS

PS(18:1(9Z)/18:1(9Z))

Piffoux M, Silva AKA, Wilhelm C, Gazeau F, Tareste D. Modification of Extracellular Vesicles by Fusion with Liposomes for the Design of Personalized Biogenic Drug Delivery Systems. ACS Nano. 2018 Jul 10. doi: 10.1021/acsnano.8b02053. [Epub ahead of print]

PubMed ID: 29975503

Parkkila P, Elderdfi M, Bunker A, Viitala T. Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements. Langmuir. 2018 Jun 25. doi: 10.1021/acs.langmuir.8b01259. [Epub ahead of print]

PubMed ID: 29894192

Parkkila P, Elderdfi M, Bunker A, Viitala T. Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements. Langmuir. 2018 Jun 25. doi: 10.1021/acs.langmuir.8b01259. [Epub ahead of print]

PubMed ID: 29894192

Parkkila P, Elderdfi M, Bunker A, Viitala T. Biophysical characterization of supported lipid bilayers using parallel dual-wavelength surface plasmon resonance and quartz crystal microbalance measurements. Langmuir. 2018 Jun 12. doi: 10.1021/acs.langmuir.8b01259. [Epub ahead of print]

PubMed ID: 29894192

Liu Y, Liu J. Cu2+-Directed Liposome Membrane Fusion, Positive-Stain Electron Microscopy, and Oxidation. Langmuir. 2018 Jun 12. doi: 10.1021/acs.langmuir.8b00864. [Epub ahead of print]

PubMed ID: 29804456

Ramakrishnan S, Gohlke A, Li F, Coleman J, Xu W, Rothman JE, Pincet F. High-Throughput Monitoring of Single Vesicle Fusion Using Freestanding Membranes and Automated Analysis. Langmuir. 2018 May 9. doi: 10.1021/acs.langmuir.8b00116. [Epub ahead of print]

PubMed ID: 29694054

Gautam K. Samdani, D. Julian McClements, and Eric A. Decker. Impact of Phospholipids and Tocopherols on the Oxidative Stability of Soybean Oil-in-Water Emulsions. J. Agric. Food Chem., Article ASAP

PubMed ID: 29629560

Phosphatidylserine Allows Observation of the Calcium–Myristoyl Switch of Recoverin and Its Preferential Binding Philippe Calvez, Thaís F. Schmidt, Line Cantin, Kristina Klinker and Christian Salesse J. Am. Chem. Soc., Article ASAP Publication Date (Web): October 11, 2016

PubMed ID: 27689444

Vamparys, L., R. Gautier, S. Vanni, W.F. Bennett, D.P. Tieleman, B. Antonny, C. Etchebest, and P.F. Fuchs. (2013). Conical Lipids in Flat Bilayers Induce Packing Defects Similar to that Induced by Positive Curvature. Biophys J 104:585-93.

PubMed ID: 23442909

Leventis, P.A., Grinstein, S. (2010) The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys. 39:407-27. Review.

PubMed ID: 20192774

Toshihiko Oka, Moynul Hasan, Md. Zahidul Islam, Md. Moniruzzaman, and Masahito Yamazaki. Low pH-Induced Lamellar to Bicontinuous Primitive Cubic Phase Transition in Dioleoylphosphatidylserine/Monoolein. Langmuir, Just Accepted Manuscript

PubMed ID: 28967756

Baharan Ali Doosti, Weria Pezeshkian, Dennis S. Bruhn John H. Ipsen, Himanshu Khandelia, Gavin D. M. Jeffries, and Tatsiana Lobovkina Membrane Tubulation in Lipid Vesicles Triggered by the Local Application of Calcium Ions. Langmuir, Article ASAP

PubMed ID: 28910109

Biswas KH, Jackman JA, Park JH, Groves JT, Cho NJ Interfacial Forces Dictate the Pathway of Phospholipid Vesicle Adsorption onto Silicon Dioxide Surfaces. Langmuir. 2018 Jan 11. doi: 10.1021/acs.langmuir.7b03799.

PubMed ID: 29281791