840034 | 16:0-18:1 PS (POPS)

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)


Powder

Size SKU Packaging Price
10mg 840034P-10mg 840034P-10mg 1 x 10mg $85.10
25mg 840034P-25mg 840034P-25mg 1 x 25mg $132.25
200mg 840034P-200mg 840034P-200mg 2 x 100mg $678.00
500mg 840034P-500mg 840034P-500mg 5 x 100mg $1,275.00

Chloroform

Size SKU Packaging Price
10mg 840034C-10mg 840034C-10mg 1 x 10mg 10mg/mL 1mL $85.10
25mg 840034C-25mg 840034C-25mg 1 x 25mg 10mg/mL 2.5mL $132.25
200mg 840034C-200mg 840034C-200mg 2 x 100mg 25mg/mL 4mL $678.00
500mg 840034C-500mg 840034C-500mg 5 x 100mg 25mg/mL 4mL $1,275.00
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16:0-18:1 PS (POPS)

16:0-18:1 PS (POPS)

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C40H75NO10PNa
Percent Composition
C 61.28%, H 9.64%, N 1.79%, Na 2.93%, O 20.41%, P 3.95%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
321863-21-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
783.988
Exact Mass
783.503
Synonyms
<p>1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt)POPSPS(16:0/18:1(9Z)) 110669</p>

Faizullin D, Valiullina Y, Salnikov V, Zuev Y. Direct interaction of fibrinogen with lipid microparticles modulates clotting kinetics and clot structure. Nanomedicine. 2019 Oct 23;23:102098. doi: 10.1016/j.nano.2019.102098. [Epub ahead of print]

PubMed ID: 31655206

Cash JN, Urata S, Li S, Ravala SK, Avramova LV, Shost MD, Gutkind JS, Tesmer JJG, Cianfrocco MA. Cryo-electron microscopy structure and analysis of the P-Rex1-Gβγ signaling scaffold. Sci Adv. 2019 Oct 16;5(10):eaax8855. doi: 10.1126/sciadv.aax8855. eCollection 2019 Oct.

PubMed ID: 31663027

R Arnold W, Zelasko S, D Meling D, Sam K, Das A. Polymorphisms of CYP2C8 Alter First-Electron Transfer Kinetics and Increase Catalytic Uncoupling. Int J Mol Sci. 2019 Sep 18;20(18). pii: E4626. doi: 10.3390/ijms20184626.

PubMed ID: 31540428

Pang SS, Bayly-Jones C, Radjainia M, Spicer BA, Law RHP, Hodel AW, Parsons ES, Ekkel SM, Conroy PJ, Ramm G, Venugopal H, Bird PI, Hoogenboom BW, Voskoboinik I, Gambin Y, Sierecki E, Dunstone MA, Whisstock JC. The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun. 2019 Sep 19;10(1):4288. doi: 10.1038/s41467-019-12279-2.

PubMed ID: 31537793

Nakagawara C, Arioka M. Distinct enzymatic and cellular characteristics of two phospholipases A1 in Aspergillus oryzae. Biochem Biophys Res Commun. 2019 Oct 22;518(4):644-650. doi: 10.1016/j.bbrc.2019.08.087. Epub 2019 Aug 26.

PubMed ID: 31466721

Melcrová A, Pokorna S, Vošahlíková M, Sýkora J, Svoboda P, Hof M, Cwiklik L, Jurkiewicz P. Concurrent Compression of Phospholipid Membranes by Calcium and Cholesterol. Langmuir. 2019 Sep 3;35(35):11358-11368. doi: 10.1021/acs.langmuir.9b00477. Epub 2019 Aug 23.

PubMed ID: 31393734

Vernen F, Harvey PJ, Dias SA, Veiga AS, Huang YH, Craik DJ, Lawrence N, Troeira Henriques S. Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties. Int J Mol Sci. 2019 Aug 26;20(17). pii: E4184. doi: 10.3390/ijms20174184.

PubMed ID: 31455019

Philippe GJ, Gaspar D, Sheng C, Huang YH, Benfield AH, Condon ND, Weidmann J, Lawrence N, Löwer A, Castanho MARB, Craik DJ, Troeira Henriques S. Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix-Loop-Helix Peptides with Cell Penetrating and Tumor Suppressor Properties. ACS Chem Biol. 2019 Sep 20;14(9):2071-2087. doi: 10.1021/acschembio.9b00593. Epub 2019 Aug 21.

PubMed ID: 31390185

Matscheko N, Mayrhofer P, Rao Y, Beier V, Wollert T. Atg11 tethers Atg9 vesicles to initiate selective autophagy. PLoS Biol. 2019 Jul 29;17(7):e3000377. doi: 10.1371/journal.pbio.3000377. eCollection 2019 Jul.

PubMed ID: 31356628

Kawano K, Ogushi M, Masuda T, Futaki S. Development of a membrane curvature-sensing peptide based on a structure-activity correlation study. Chem Pharm Bull (Tokyo). 2019 Jul 17. doi: 10.1248/cpb.c19-00465. [Epub ahead of print]

PubMed ID: 31316036

Kumagai PS, Sousa VK, Donato M, Itri R, Beltramini LM, Araujo APU, Buerck J, Wallace BA, Lopes JLS. Unveiling the binding and orientation of the antimicrobial peptide Plantaricin 149 in zwitterionic and negatively charged membranes. Eur Biophys J. 2019 Oct;48(7):621-633. doi: 10.1007/s00249-019-01387-y. Epub 2019 Jul 19.

PubMed ID: 31324942

Cho HJ, Yoon H, Lee HH. Phosphatidylserine-induced dissociation of the heterodimeric PstB2p/Pbi1p complex in yeast phosphatidylserine trafficking system. Biochem Biophys Res Commun. 2019 Sep 17;517(2):285-290. doi: 10.1016/j.bbrc.2019.07.066. Epub 2019 Jul 24.

PubMed ID: 31351588

Mayer SF, Ducrey J, Dupasquier J, Haeni L, Rothen-Rutishauser B, Yang J, Fennouri A, Mayer M. Targeting specific membranes with an azide derivative of the pore-forming peptide ceratotoxin A. Biochim Biophys Acta Biomembr. 2019 Oct 1;1861(10):183023. doi: 10.1016/j.bbamem.2019.07.011. Epub 2019 Jul 17.

PubMed ID: 31325418

Melcrová A, Pokorna S, Vošahlíková M, Sýkora J, Svoboda P, Hof M, Cwiklik L, Jurkiewicz P. Concurrent Compression of Phospholipid Membranes by Calcium and Cholesterol. Langmuir. 2019 Sep 3;35(35):11358-11368. doi: 10.1021/acs.langmuir.9b00477. Epub 2019 Aug 23.

PubMed ID: 31393734

Patrick JW, Laganowsky A. Probing Heterogeneous Lipid Interactions with Membrane Proteins Using Mass Spectrometry. Methods Mol Biol. 2019;2003:175-190. doi: 10.1007/978-1-4939-9512-7_9.

PubMed ID: 31218619

Lv Z, Hashemi M, Banerjee S, Zagorski K, Rochet JC, Lyubchenko YL. Assembly of α-synuclein aggregates on phospholipid bilayers. Biochim Biophys Acta Proteins Proteom. 2019 Sep;1867(9):802-812. doi: 10.1016/j.bbapap.2019.06.006. Epub 2019 Jun 19.

PubMed ID: 31226488

Damiati SA, Alaofi AL, Dhar P, Alhakamy NA. Novel machine learning application for prediction of membrane insertion potential of cell-penetrating peptides. Int J Pharm. 2019 Aug 15;567:118453. doi: 10.1016/j.ijpharm.2019.118453. Epub 2019 Jun 21.

PubMed ID: 31233847

Bradberry MM, Bao H, Lou X, Chapman ER. Phosphatidylinositol 4,5-bisphosphate drives Ca2+-independent membrane penetration by the tandem C2 domain proteins synaptotagmin-1 and Doc2β. J Biol Chem. 2019 Jul 12;294(28):10942-10953. doi: 10.1074/jbc.RA119.007929. Epub 2019 May 30.

PubMed ID: 31147445

Ahlem Eddehech, Nabil Smichi, Yani Arhab, Alexandre Noiriel, Abdelkarim Abousalham, Youssef Gargouri, Zied Zarai. Production, purification and functional characterization of phospholipase C from Bacillus thuringiensis with high catalytic activity. Process Biochemistry. 2019 August;83:122-130. doi: 10.1016/j.procbio.2019.05.012


Garg S, Liu Y, Perez-Salas U, Porcar L, Butler PD. Anomalous inter-membrane cholesterol transport in fluid phase phosphoserine vesicles driven by headgroup ordered to disordered entropic transition. Chem Phys Lipids. 2019 May 31;223:104779. doi: 10.1016/j.chemphyslip.2019.05.004. [Epub ahead of print]

PubMed ID: 31153912

Colombo S, Criscuolo A, Zeller M, Fedorova M, Domingues MR, Domingues P. Analysis of oxidised and glycated aminophospholipids: Complete structural characterisation by C30 liquid chromatography-high resolution tandem mass spectrometry. Free Radic Biol Med. 2019 May 28. pii: S0891-5849(19)30356-9. doi: 10.1016/j.freeradbiomed.2019.05.025. [Epub ahead of print]

PubMed ID: 31150763

Basu SS, McMinn MH, Giménez-Cassina Lopéz B, Regan MS, Randall EC, Clark AR, Cox CR, Agar NYR. Metal Oxide Laser Ionization Mass Spectrometry Imaging (MOLI MSI) Using Cerium(IV) Oxide. Anal Chem. 2019 May 21;91(10):6800-6807. doi: 10.1021/acs.analchem.9b00894. Epub 2019 May 8.

PubMed ID: 31025851

Harsini FM, Bui AA, Rice AM, Chebrolu S, Fuson KL, Turtoi A, Bradberry M, Chapman ER, Sutton RB. Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin. J Mol Biol. 2019 Apr 18. pii: S0022-2836(19)30188-3. doi: 10.1016/j.jmb.2019.04.006. [Epub ahead of print]

PubMed ID: 31004665

Huff HC, Maroutsos D, Das A. Lipid composition and macromolecular crowding effects on CYP2J2-mediated drug metabolism in nanodiscs. Protein Sci. 2019 May;28(5):928-940. doi: 10.1002/pro.3603. Epub 2019 Apr 1.

PubMed ID: 30861250

Gomes B, Sanna G, Madeddu S, Hollmann A, Santos NC. Combining 25-Hydroxycholesterol with an HIV Fusion Inhibitor Peptide: Interaction with Biomembrane Model Systems and Human Blood Cells. ACS Infect Dis. 2019 Apr 12;5(4):582-591. doi: 10.1021/acsinfecdis.8b00321. Epub 2019 Feb 28.

PubMed ID: 30816690

Hubrich R, Park Y, Mey I, Jahn R, Steinem C. SNARE-Mediated Fusion of Single Chromaffin Granules with Pore-Spanning Membranes. Biophys J. 2019 Jan 22;116(2):308-318. doi: 10.1016/j.bpj.2018.11.3138. Epub 2018 Dec 8.

PubMed ID: 30598283

Scott HL, Heberle FA, Katsaras J, Barrera FN. Phosphatidylserine Asymmetry Promotes the Membrane Insertion of a Transmembrane Helix. Biophys J. 2019 Mar 19. pii: S0006-3495(19)30189-4. doi: 10.1016/j.bpj.2019.03.003. [Epub ahead of print]

PubMed ID: 30954213

Ruokonen SK, Ekholm FS, Wiedmer SK. Assessing the Interactions of Auristatin Derivatives with Mixed Phospholipid-Sodium Dodecyl Sulfate Aggregate Dispersions. Langmuir. 2019 Apr 16;35(15):5232-5240. doi: 10.1021/acs.langmuir.9b00116. Epub 2019 Apr 3.

PubMed ID: 30889955

Ruokonen SK, Ekholm FS, Wiedmer SK. Assessing the Interactions of Auristatin Derivatives with Mixed Phospholipid-Sodium Dodecyl Sulfate Aggregate Dispersions. Langmuir. 2019 Apr 3. doi: 10.1021/acs.langmuir.9b00116. [Epub ahead of print]

PubMed ID: 30889955

Maroutsos D, Huff H, Das A. Bacterial Expression of Membrane-Associated Cytochrome P450s and Their Activity Assay in Nanodiscs. Methods Mol Biol. 2019;1927:47-72. doi: 10.1007/978-1-4939-9142-6_5.

PubMed ID: 30788785

Bian X, De Camilli P. In Vitro Assays to Measure the Membrane Tethering and Lipid Transport Activities of the Extended Synaptotagmins. Methods Mol Biol. 2019;1949:201-212. doi: 10.1007/978-1-4939-9136-5_15.

PubMed ID: 30790258

Agamasu C, Ghirlando R, Taylor T, Messing S, Tran TH, Bindu L, Tonelli M, Nissley DV, McCormick F4, Stephen AG. KRAS Prenylation Is Required for Bivalent Binding with Calmodulin in a Nucleotide-Independent Manner. Biophys J. 2019 Mar 19;116(6):1049-1063. doi: 10.1016/j.bpj.2019.02.004. Epub 2019 Feb 15.

PubMed ID: 30846362

Sugiura T, Takahashi C, Chuma Y, Fukuda M, Yamada M, Yoshida U, Nakao H, Ikeda K, Khan D, Nile AH, Bankaitis VA, Nakano M. Biophysical Parameters of the Sec14 Phospholipid Exchange Cycle. Biophys J. 2019 Jan 8;116(1):92-103. doi: 10.1016/j.bpj.2018.11.3131. Epub 2018 Dec 4.

PubMed ID: 30580923

Nyholm TKM, Jaikishan S, Engberg O, Hautala V, Slotte JP. The Affinity of Sterols for Different Phospholipid Classes and Its Impact on Lateral Segregation. Biophys J. 2019 Jan 22;116(2):296-307. doi: 10.1016/j.bpj.2018.11.3135. Epub 2018 Dec 6.

PubMed ID: 30583790

Chalupska D, Różycki B, Humpolickova J, Faltova L, Klima M, Boura E. Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins. Sci Rep. 2019 Jan 24;9(1):567. doi: 10.1038/s41598-018-37158-6.

PubMed ID: 30679637

Lokova AY, Zaborova OV. Modification of fliposomes with a polycation can enhance the control of pH-induced release. Int J Nanomedicine. 2019 Feb 8;14:1039-1049. doi: 10.2147/IJN.S190306. eCollection 2019.

PubMed ID: 30804669

Neves B, Domingues P, Oliveira MM, Domingues MDR, Melo T. Profile of Phosphatidylserine Modifications under Nitroxidative Stress Conditions Using a Liquid Chromatography-Mass Spectrometry Based Approach. Molecules. 2018 Dec 29;24(1). pii: E107. doi: 10.3390/molecules24010107.

PubMed ID: 30597957

Ruchala P, Waring AJ, Cilluffo M, Whitelegge JP, Gundersen CB. Insights into the structure and molecular topography of the fatty acylated domain of synaptotagmin-1.Biochim Biophys Acta Biomembr. 2019 Mar 1;1861(3):677-684. doi: 10.1016/j.bbamem.2018.12.019. Epub 2019 Jan 4.

PubMed ID: 30615859

Florian Scheffler, Mandy Brueckner, Jingjing Ye, Ralf Seidel, and Uta Reibetanz. A Hybrid Carrier System Based on Origami Nanostrucutures and Layer&dash;by&dash;Layer Microparticles. Advanced Functional Materials. 2019 Jan 09. doi: 10.1002/adfm.201808116


He X, Zhang Q. Synthesis, Purification, and Mass Spectrometric Characterization of Stable Isotope-Labeled Amadori-Glycated Phospholipids. ACS Omega. 2018 Nov 30;3(11):15725-15733. doi: 10.1021/acsomega.8b01893. Epub 2018 Nov 19.

PubMed ID: 30533579

Li P, Wang J, Zou Y, Sun Z, Zhang M, Geng Z, Xu W, Wang D. Interaction of Hsp90AA1 with phospholipids stabilizes membranes under stress conditions. Biochim Biophys Acta Biomembr. 2019 Feb 1;1861(2):457-465. doi: 10.1016/j.bbamem.2018.11.009. Epub 2018 Dec 2.

PubMed ID: 30517848

Lawrence N, Wu B, Ligutti J, Cheneval O, Agwa AJ, Benfield AH, Biswas K, Craik DJ, Miranda LP, Troeira Henriques S, Schroeder CI. Peptide-membrane interactions affect the inhibitory potency and selectivity of spider toxins ProTx-II and GpTx-1. ACS Chem Biol. 2018 Dec 3. doi: 10.1021/acschembio.8b00989. [Epub ahead of print].

PubMed ID: 30507158

Li Y, Soubias O, Li J1, Sun S, Randazzo PA, Byrd RA. Functional Expression and Characterization of Human Myristoylated-Arf1 in Nanodisc Membrane Mimetics. Biochemistry. 2019 Feb 20. doi: 10.1021/acs.biochem.8b01323. [Epub ahead of print]

PubMed ID: 30735034

Lin CC, Bachmann M, Bachler S, Venkatesan K, Dittrich PS. Tunable Membrane Potential Reconstituted in Giant Vesicles Promotes Permeation of Cationic Peptides at Nanomolar Concentrations. ACS Appl Mater Interfaces. 2018 Nov 19. doi: 10.1021/acsami.8b12217. [Epub ahead of print].

PubMed ID: 30450894

Kawanabe A, Hashimoto M, Nishizawa M, Nishizawa K, Narita H, Yonezawa T, Jinno Y, Sakata S, Nakagawa A, Okamura Y. The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase. Elife. 2018 Nov 28;7. pii: e41653. doi: 10.7554/eLife.41653.

PubMed ID: 30484774

Thomas LL, van der Vegt SA, Fromme JC. A Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF. Dev Cell. 2019 Jan 7;48(1):100-114.e9. doi: 10.1016/j.devcel.2018.11.013. Epub 2018 Dec 6.

PubMed ID: 30528786

Kourtzelis I, Li X, Mitroulis I, Grosser D, Kajikawa T, Wang B, Grzybek M, von Renesse J, Czogalla A, Troullinaki M, Ferreira A, Doreth C, Ruppova K, Chen LS, Hosur K, Lim JH, Chung KJ, Grossklaus S, Tausche AK, Joosten LAB, Moutsopoulos NM, Wielockx B, Castrillo A, Korostoff JM, Coskun Ü, Hajishengallis G, Chavakis T. DEL-1 promotes macrophage efferocytosis and clearance of inflammation. Nat Immunol. 2019 Jan;20(1):40-49. doi: 10.1038/s41590-018-0249-1. Epub 2018 Nov 19.

PubMed ID: 30455459

Nyholm TKM, Jaikishan S, Engberg O, Hautala V, Slotte JP. The Affinity of Sterols for Different Phospholipid Classes and Its Impact on Lateral Segregation. Biophys J. 2019 Jan 22;116(2):296-307. doi: 10.1016/j.bpj.2018.11.3135. Epub 2018 Dec 6.

PubMed ID: 30583790

Drechsler C, Markones M, Choi JY, Frieling N, Fiedler S, Voelker DR, Schubert R, Heerklotz H. Preparation of Asymmetric Liposomes Using a Phosphatidylserine Decarboxylase. Biophys J. 2018 Oct 16;115(8):1509-1517. doi: 10.1016/j.bpj.2018.08.036. Epub 2018 Sep 1.

PubMed ID: 30266319

Zong W, Thingholm B, Itel F, Schattling PS, Brodszkij E, Mayer D, Stenger S, Goldie KN, Han X, Städler B. Phospholipid-Block Copolymer Hybrid Vesicles with Lysosomal Escape Ability. Langmuir. 2018 Jun 1. doi: 10.1021/acs.langmuir.8b01073. [Epub ahead of print]

PubMed ID: 29776311

What Is the Preferred Conformation of Phosphatidylserine–Copper(II) Complexes? A Combined Theoretical and Experimental Investigation Kari Kusler, Samuel O. Odoh, Alexey Silakov, Matthew F. Poyton, Saranya Pullanchery, Paul S. Cremer and Laura Gagliardi J. Phys. Chem. B, Article ASAP DOI: 10.1021/acs.jpcb.6b10675

PubMed ID: 27957849

Leventis, P.A., Grinstein, S. (2010) The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys. 39:407-27. Review.

PubMed ID: 20192774

Saba Ghazvini, Ryan Alonso, Nabil Alhakamy, and Prajnaparamita Dhar. pH induced changes in the surface viscosity of unsaturated phospholipids monitored using active interfacial microrheology. Langmuir, Just Accepted Manuscript

PubMed ID: 29019691

Maria J. Sarmento, Ana Coutinho, Aleksander Fedorov, Manuel Prieto, and Fabio Fernandes. Membrane Order Is a Key Regulator of Divalent Cation-Induced Clustering of PI(3,5)P2 and PI(4,5)P2. Langmuir. Article ASAP. [PubMed]

PubMed ID: 28961003

Li G, Kim J, Huang Z, St Clair JR, Brown DA, London E. Efficient replacement of plasma membrane outer leaflet phospholipids and sphingolipids in cells with exogenous lipids. Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):14025-14030. Epub 2016 Nov 21

PubMed ID: 27872310