810890 | Fluorescent DOTAP

1-oleoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-3-trimethylammonium propane (chloride salt)

Fluorescent DOTAP

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Size SKU Packaging Price
50µg 810890P-50ug 810890P-50ug $1,430.50

Info

Fluorescent DOTAP

1-oleoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-3-trimethylammonium propane (chloride salt)

DOTAP is one of the most widely used cationic lipids for gene transfection applications. DOTAP is proven to be efficient for in vitro and in vivo transfection applications. Various analogues of TAP are available for structure-activity relationship studies.

Simberg D, Weisman S, Talmon Y, Barenholz Y. DOTAP (and other cationic lipids): chemistry, biophysics, and transfection. Crit Rev Ther Drug Carrier Syst. 2004;21(4):257-317. doi: 10.1615/critrevtherdrugcarriersyst.v21.i4.10. PMID: 15638468.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H60ClN5O7
Percent Composition
C 60.87%, H 8.51%, Cl 4.99%, N 9.86%, O 15.77%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1010076-97-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
710.344
Exact Mass
709.418
Synonyms
18:1-06:0 NBD DOTAP
References

Bae CS, Ahn T. Diacylglycerol in Cationic Nanoparticles Stimulates Oxidative Stress-Mediated Death of Cancer Cells. Lipids. 2018 Nov;53(11-12):1059-1067. doi: 10.1002/lipd.12124. Epub 2019 Jan 24. PMID: 30680740.

PubMed ID: 30680740
Certificates of Analysis
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