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PyrOVPC (DMA) | 810306



Methylene Chloride


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  • Data
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  • Reference
  • Deprotection Procedure
Molecular Formula
Percent Composition
C 65.15%, H 7.73%, N 1.85%, O 21.17%, P 4.10%
1 Years
CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
Exact Mass
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Moumtzi, A., M. Trenker, K. Flicker, E. Zenzmaier, R. Saf, and A. Hermetter. (2007). Import and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells. J Lipid Res 48:565-82. [PubMed]
Note: Perform all operations in a fume hood.
(1) Open glass ampoule and transfer the contents of the ampoule to the Teflon vial (included) using a glass pipette or syringe. DO NOT USE PLASTIC. (2) Evaporate the dichloromethane under a gentle stream of nitrogen at room temperature. (3) Add 300µL of 200mM HCl in THF (see below for preparation) and stir/agitate for 1 hour. (4) Neutralize the reaction mixture with 10mg of NaHCO3 solid (5) Extract the aldehyde product with 900µL of CHCl3/MeOH ( 2:1, v/v). (6) Wash the resulting organic phase twice with 250 µL of water (7) Dry the organic phase over Na2SO4, filter, and evaporate organic solvent under a gentle stream of nitrogen at room temperature. This procedure will yield ~1mg of aldehyde product. (8)  Once deprotected, we recommend that PyrOVPC be used immediately.
Preparation of 200mM HCl in THF: 2mL of 1N aq HCl was diluted with 8mL of THF.