810298 | 18:1-18:1-C11 TopFluor® TG

1,2-dioleoyl-3-[11-(dipyrrometheneboron difluoride)undecanoyl]-sn-glycerol


Chloroform

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1mg 810298C-1mg 810298C-1mg 1 x 1mg 1mg/mL 1mL $152.00
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18:1-18:1-C11 TopFluor® TG

18:1-18:1-C11 TopFluor® TG

1,2-dioleoyl-3-[11-(dipyrrometheneboron difluoride)undecanoyl]-sn-glycerol

Lipid droplets (LDs) are organelles that store lipids as reservoirs of metabolic energy and membrane lipid precursors, and they have been identified in the nucleus of some cells. LDs can be found in most eukaryotic cells. Most prominent are LDs in adipocytes, which make up most of the cellular volume, but other metabolically active cell types, such as liver or muscle cells, also have abundant LDs.
LDs are unusual organelles in that they are bound by a monolayer of surface phospholipids, into which specific proteins are embedded, such as perilipins and metabolic enzymes. The cell biology of LDs as cellular organelles is only beginning to be unraveled. Avanti now offers a series of fluorescently-labeled mono-, di-, and triglycerides, which are useful for studying these important cellular organelles.

Hygroscopic
Yes
Light Sensitive
Yes
Molecular Formula
C63H105 BF2N2O6
Percent Composition
C 73.09%, H 10.22%. B 1.04%, F 3.67%, N 2.71%, O 9.27%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°
Molecular Weight
1035.325
Exact Mass
1034.803

Kory, N., R.V. Farese Jr, and T.C. Walther. (2016). Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets. Trends Cell Biol

PubMed ID: 26995697

Farese, R.V. Jr and T.C. Walther. (2016). Lipid droplets go nuclear. J Cell Biol 212:7-8.

PubMed ID: 26728852

Farese, R.V. Jr and T.C. Walther. (2009). Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 139:855-60.

PubMed ID: 19945371

Ohsaki, Y., T. Kawai, Y. Yoshikawa, J. Cheng, E. Jokitalo, and T. Fujimoto. (2016). PML isoform II plays a critical role in nuclear lipid droplet formation. J Cell Biol 212:29-38.

PubMed ID: 26728854

Kory, N., A.R. Thiam, R.V. Farese Jr, and T.C. Walther. (2015). Protein Crowding Is a Determinant of Lipid Droplet Protein Composition. Dev Cell 34:351-63.

PubMed ID: 26212136

Sæle Ø, Rød KEL, Quinlivan VH, Li S, Farber SA. A novel system to quantify intestinal lipid digestion and transport. Biochim Biophys Acta. 2018 May 17. pii: S1388-1981(18)30098-2. doi: 10.1016/j.bbalip.2018.05.006.

PubMed ID: 29778665