18:1-C4 TopFluor DG | 810294
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- Lipid droplets (LDs) are organelles that store lipids as reservoirs of metabolic energy and membrane lipid precursors, and they have been identified in the nucleus of some cells. LDs can be found in most eukaryotic cells. Most prominent are LDs in adipocytes, which make up most of the cellular volume, but other metabolically active cell types, such as liver or muscle cells, also have abundant LDs.
LDs are unusual organelles in that they are bound by a monolayer of surface phospholipids, into which specific proteins are embedded, such as perilipins and metabolic enzymes. The cell biology of LDs as cellular organelles is only beginning to be unraveled. Avanti now offers a series of fluorescently-labeled mono-, di-, and triglycerides, which are useful for studying these important cellular organelles.
- Molecular Formula
- C38H59 BF2N2O5
- Percent Composition
- C 67.85%, H 8.84%, B 1.61%, F 5.65%, N 4.16%, O 11.89%
- 6 months
- Molecular Weight
- Exact Mass
- 495/503 nm
Farese, R.V. Jr and T.C. Walther. (2016). Lipid droplets go nuclear. J Cell Biol 212:7-8. [PubMed]
Kory, N., A.R. Thiam, R.V. Farese Jr, and T.C. Walther. (2015). Protein Crowding Is a Determinant of Lipid Droplet Protein Composition. Dev Cell 34:351-63. [PubMed]
Farese, R.V. Jr and T.C. Walther. (2009). Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 139:855-60. [PubMed]
Ohsaki, Y., T. Kawai, Y. Yoshikawa, J. Cheng, E. Jokitalo, and T. Fujimoto. (2016). PML isoform II plays a critical role in nuclear lipid droplet formation. J Cell Biol 212:29-38. [PubMed]