810294 | 18:1-C4 TopFluor® DG

1-oleoyl-3-[4-(dipyrrometheneboron difluoride)butanoyl]-rac-glycerol


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1mg 810294P-1mg 810294P-1mg 1 x 1mg $220.63
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18:1-C4 TopFluor® DG

18:1-C4 TopFluor® DG

1-oleoyl-3-[4-(dipyrrometheneboron difluoride)butanoyl]-rac-glycerol

Lipid droplets (LDs) are organelles that store lipids as reservoirs of metabolic energy and membrane lipid precursors, and they have been identified in the nucleus of some cells. LDs can be found in most eukaryotic cells. Most prominent are LDs in adipocytes, which make up most of the cellular volume, but other metabolically active cell types, such as liver or muscle cells, also have abundant LDs.
LDs are unusual organelles in that they are bound by a monolayer of surface phospholipids, into which specific proteins are embedded, such as perilipins and metabolic enzymes. The cell biology of LDs as cellular organelles is only beginning to be unraveled. Avanti now offers a series of fluorescently-labeled mono-, di-, and triglycerides, which are useful for studying these important cellular organelles.

Hygroscopic
Yes
Light Sensitive
Yes
Molecular Formula
C38H59 BF2N2O5
Percent Composition
C 67.85%, H 8.84%, B 1.61%, F 5.65%, N 4.16%, O 11.89%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
2260795-62-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
672.693
Exact Mass
672.449

Kory N, Farese RV Jr, Walther TC. Targeting Fat: Mechanisms of Protein Localization to Lipid Droplets. Trends Cell Biol. 2016 Jul;26(7):535-546. doi: 10.1016/j.tcb.2016.02.007. Epub 2016 Mar 16. PMID: 26995697; PMCID: PMC4976449.

PubMed ID: 26995697

Farese RV Jr, Walther TC. Lipid droplets go nuclear. J Cell Biol. 2016 Jan 4;212(1):7-8. doi: 10.1083/jcb.201512056. PMID: 26728852; PMCID: PMC4700486.

PubMed ID: 26728852

Kory N, Thiam AR, Farese RV Jr, Walther TC. Protein Crowding Is a Determinant of Lipid Droplet Protein Composition. Dev Cell. 2015 Aug 10;34(3):351-63. doi: 10.1016/j.devcel.2015.06.007. Epub 2015 Jul 23. PMID: 26212136; PMCID: PMC4536137.

PubMed ID: 26212136

Farese RV Jr, Walther TC. Lipid droplets finally get a little R-E-S-P-E-C-T. Cell. 2009 Nov 25;139(5):855-60. doi: 10.1016/j.cell.2009.11.005. PMID: 19945371; PMCID: PMC3097139.

PubMed ID: 19945371

Ohsaki Y, Kawai T, Yoshikawa Y, Cheng J, Jokitalo E, Fujimoto T. PML isoform II plays a critical role in nuclear lipid droplet formation. J Cell Biol. 2016 Jan 4;212(1):29-38. doi: 10.1083/jcb.201507122. PMID: 26728854; PMCID: PMC4700481.

PubMed ID: 26728854