810284 | TopFluor® Lyso PC

1-(dipyrrometheneboron difluoride)undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine


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TopFluor® Lyso PC

TopFluor® Lyso PC

1-(dipyrrometheneboron difluoride)undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

Fluorescent derivative of lyso phosphatidylcholine with spectral properties similar to BODIPY-FL.

Hygroscopic
No
Light Sensitive
Yes
Molecular Formula
C32H53BF2N3O7P
Percent Composition
C 57.23%, H 7.95%, B 1.61%, F 5.66%, N 6.26%, O 16.68%, P 4.61%
Purity
>99% LPC; may contain up to 10% of the 2-LPC isomer.
Stability
1 Year
Storage Temperature
-20°C
CAS Number
2260795-53-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
671.561
Exact Mass
671.368

Jia Zhou, Xiaojing Chi, Min Cheng, Xingyao Huang, Xiuying Liu, Jingjing Fan, Hua Xu, Tianli Lin, Lei Shi, Chengfeng Qin, Wei Yang. Zika virus degrades the w-3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis. Zhou et al., Sci. Adv. 2019; 5 : eaax7142 23 October 2019.


Chagas-Lima AC, Pereira MG, Fampa P, Lima MS, Kluck GEG, Atella GC. Bioactive lipids regulate Trypanosoma cruzi development. Parasitol Res. 2019 Sep;118(9):2609-2619. doi: 10.1007/s00436-019-06331-9. Epub 2019 Jul 2.

PubMed ID: 31267245

Wu D, Jin X, Wang X, Ma B, Lou C, Qu H, Zheng J, Zhang B, Yan X, Wang Y, Jing L. Engineering temperature-sensitive plateletsomes as a tailored chemotherapy platform in combination with HIFU ablation for cancer treatment. Theranostics. 2019 May 31;9(13):3966-3979. doi: 10.7150/thno.32172. eCollection 2019.

PubMed ID: 31281525

Piccirillo AR, Hyzny E1, Beppu LY, Menk AV, Wallace CT, Hawse WF, Buechel HM, Wong BH, Foo JC, Cazenave-Gassiot A, Wenk MR, Delgoffe GM, Watkins SC, Silver DL, D'Cruz LM. The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection. J Immunol. 2019 Jul 1;203(1):117-126. doi: 10.4049/jimmunol.1801585. Epub 2019 May 24.

PubMed ID: 31127034

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