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TopFluor Cholesterol | 810255

23-(dipyrrometheneboron difluoride)-24-norcholesterol

810255P

Powder

1 mg
$189.00
5 mg
$389.00
10 mg
$704.00

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  • Data
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  • Reference
  • Spectrum
Molecular Formula
C36H51BF2N2O
Percent Composition
C 74.99%, H 8.92%, B 1.87%, F 6.59%, N 4.86%, O 2.77%
Purity
>99%
Stability
1 Year
Storage
-20°C
CAS Number
878557-19-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
576.611
Exact Mass
576.406
Ex/Em
495nm/507nm
Synonyms
Bodipy Cholesterol
Bdp-Chol
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Z. Li, E. Mintzer, and R. Bittman, “First Synthesis of Free Cholesterol – BODIPY Conjugates,” J. Org. Chem. 71, 1718-1721 (2006). [PubMed] F. S. Ariola, Z. Li, C. Cornejo, R. Bittman, and A. A. Heikal, “Membrane Fluidity and Lipid Order in Ternary Giant Unilamellar Vesicles Using a New Bodipy-Cholesterol Derivative,” Biophys J. 96, 2696-2708 (2009). [PubMed] D. L. Marks, R. Bittman, and R. E. Pagano, “Use of Bodipy-labeled Sphingolipid and Cholesterol Analogs to Examine Membrane Microdomains in Cells,” Histochem. Cell Biol. 130, 819-832 (2008). [PubMed] M. Hölttä-Vuori, R. L. Uronen, J. Repakova, E. Salonen, I. Vattulainen, P. Panula, Z. Li, R. Bittman, and E. Ikonen, “BODIPY-Cholesterol: A New Tool to Visualize Sterol Trafficking in Living Cells and Organisms,” Traffic 9, 1839-1849 (2008).[PubMed] Z. Li and R. Bittman, “Synthesis and Spectral Properties of Cholesterol- and FTY720-containing Boron Dipyrromethene Dyes,” J. Org. Chem. 72, 8376-8382 (2007). [PubMed] J. E. Shaw, R. F. Epand, R. M. Epand, Z. Li, R. Bittman, and C. M. Yip, “Correlated Fluorescence-Atomic Force Microscopy of Membrane Domains: Structure of Fluorescence Probes Determines Lipid Localization,” Biophys J. 90, 2170-2178 (2006). [PubMed] J. E. Shaw, R. F. Epand, K. Sinnathamby, Z. Li, R. Bittman, R. M. Epand, and C. M. Yip, “Tracking Peptide-Membrane Interactions: Insights from in situ Coupled Confocal-Atomic Force Microscopy Imaging of NAP-22 Peptide Insertion and Assembly,” J. Struct. Biol. 155, 458-469 (2006). [PubMed] B. Y. Baker, R. F. Epand, R. M. Epand, and W. L. Miller, "Cholesterol Binding Does Not predict Activity of the Steroidogenic Acute Regulatory Protein, StAR," Biochemistry 282, 10223-10232 (2007). [PubMed] S. Chiantia, J. Ries, G. Chwastek, D. Carrer, Z. Li, R. Bittman, and P. Schwille, “Role of Ceramide in Membrane Protein Organization Investigated by Combined AFM and FCS,” Biochim. Biophys. Acta Biomembranes 1778, 1356-1364 (2008). [PubMed] K. Trajkovic, C. Hsu, S. Chianti, L. Rajendran, D. Wenzel, F. Wieland, P. Schwille, B. Brügger, and M. Simons, "Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes," Science 319, 1244-1247 (2008). [PubMed] S. Scolari, K. Müller, R. Bittman, A. Herrmann, and P. Müller, “Interaction of Mammalian Seminal Plasma Protein PDC-109 with Cholesterol – Implications for a Putative CRAC Domain,” Biochemistry 49, 9027-9031 (2010). [PubMed] M. Bidet, O. Joubert, B. Lacombe, M. Ciantar, R. Nehmé, P. Mollat, L. Bretillon, H. Faure, R. Bittman, M. Ruat, and I. Mus-Veteau, “Patched Regulates the Hedgehog Pathway via Cholesterol Efflux,” PLoS One, 6(9):e23834 (2011). [PubMed] D. Wüstner, L. Solanko, F. W. Lund, O. Garvik, Z. Li, R. Bittman, T. Korte, and A. Herrmann, “Quantitative Assessment of Sterol Traffic in Living Cells by Dual Labeling with Dehydroergosterol and BODIPY-Cholesterol,” Chem. Phys. Lipids 164, 221-235 (2011). [PubMed] S. Sankaranarayanan, G. Kellner-Weibel, M. de la Llera-Moya, M. C. Phillips, B. F. Asztalos, R. Bittman, and G. H. Rothblat, “A Sensitive Assay for ABCA1-Mediated Cholesterol Efflux Using Bodipy-Cholesterol," J. Lipid Res. 52, 2332-2340 (2011). [PubMed] C. Röhrl, C. Meisslitzer-Ruppitsch, R. Bittman, Z. Li, G. Pabst, R. Prassl, W. Strobl, J. Neumüller, A. Ellinger, M. Pavelka, and H. Stangl, “Combined Light and Electron Microscopy using Diaminobenzidine Photooxidation to Monitor Trafficking of Lipids Derived from Lipoprotein Particles,” Curr. Pharm. Biotechnol. 13, 331-340 (2012). [PubMed] Littleton, R.M., M. Miller, and J.R. Hove. (2012). Whole plant based treatment of hypercholesterolemia with Crataegus laevigata in a zebrafish model. BMC Complement Altern Med 12:105 [PubMed] Lund, F.W., M.A. Lomholt, L.M. Solanko, R. Bittman, and D. Wustner. (2012). Two-photon time-lapse microscopy of BODIPY-cholesterol reveals anomalous sterol diffusion in chinese hamster ovary cells. BMC Biophys 5:20 [PubMed] Crowley, J.T., A.M. Toledo, T.J. LaRocca, J.L. Coleman, E. London, and J.L. Benach. (2013). Lipid exchange between Borrelia burgdorferi and host cells. PLoS Pathog 9:e1003109 [PubMed]