810253 | dehydroergosterol (DHE)

ergosta-5,7,9(11),22-tetraen-3ß-ol


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dehydroergosterol (DHE)

dehydroergosterol (DHE)

ergosta-5,7,9(11),22-tetraen-3ß-ol

Hygroscopic
Yes
Light Sensitive
Yes
Molecular Formula
C28H42O
Percent Composition
C 85.22%, H 10.73%, O 4.05%
Purity
>99%
Stability
3 Months
Storage Temperature
-80°C
CAS Number
516-85-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
394.632
Exact Mass
394.324
Synonyms
DHE

Bansal S, Su WC, Budamagunta M, Xiao W, Ajena Y, Liu R, Voss JC, Carney RP, Parikh AN, Lam KS. Discovery and mechanistic characterization of a structurally-unique membrane active peptide. Biochim Biophys Acta Biomembr. 2020 Oct 1;1862(10):183394. doi: 10.1016/j.bbamem.2020.183394. Epub 2020 Jun 18. PMID: 32562695.

PubMed ID: 32562695

Kuroi K, Imaizumi M, Miura T, Nakabayashi T. Examination of the association states of dehydroergosterol towards understanding the association structures of sterols in a membrane. Biochem Biophys Res Commun. 2019 Jul 12;515(1):228-233. doi: 10.1016/j.bbrc.2019.05.109. Epub 2019 May 27.

PubMed ID: 31146916

Chauhan N, Jentsch JA, Menon AK. Measurement of Intracellular Sterol Transport in Yeast. Methods Mol Biol. 2019;1949:115-136. doi: 10.1007/978-1-4939-9136-5_10.

PubMed ID: 30790253

Koponen A, Arora A, Takahashi K, Kentala H, Kivelä AM, Jääskeläinen E, Peränen J, Somerharju P, Ikonen E, Viitala T, Olkkonen VM. ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol. Biochimie. 2019 Mar;158:90-101. doi: 10.1016/j.biochi.2018.12.013. Epub 2018 Dec 24.

PubMed ID: 30590084

Pourmousa M, Róg T, Mikkeli R, Vattulainen L, Solanko LM, Wüstner D, List NH, Kongsted J, Karttunen M. Dehydroergosterol as an analogue for cholesterol: why it mimics cholesterol so well-or does it? J Phys Chem B. 2014 Jul 3;118(26):7345-57. doi: 10.1021/jp406883k. Epub 2014 Jun 18.

PubMed ID: 24893063

Maxfield FR, Wüstner D. Analysis of cholesterol trafficking with fluorescent probes. Methods Cell Biol. 2012;108:367-93. doi: 10.1016/B978-0-12-386487-1.00017-1.

PubMed ID: 22325611

Homan R, Esmaeil N, Mendelsohn L, Kato GJ. A fluorescence method to detect and quantitate sterol esterification by lecithin:cholesterol acyltransferase. Anal Biochem. 2013 Oct 1;441(1):80-6. doi: 10.1016/j.ab.2013.06.018. Epub 2013 Jul 12.

PubMed ID: 23851343

Estronca LM, Filipe HA, Salvador A, Moreno MJ, Vaz WL. Homeostasis of free cholesterol in the blood: a preliminary evaluation and modeling of its passive transport. J Lipid Res. 2014 Jun;55(6):1033-43. doi: 10.1194/jlr.M043067. Epub 2014 Apr 7.

PubMed ID: 24711632

Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Academic Article [Link]


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