810205 | NBD Sphingosine

omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol

NBD Sphingosine

Powder

Size SKU Packaging Price
50µg 810205P-50ug 810205P-50ug $265.00
250µg 810205P-250ug 810205P-250ug $845.00

Chloroform/Methanol

Size SKU Packaging Price
250µg 810205X-250ug 810205X-250ug $845.00 845

Info

NBD Sphingosine

omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol

Data
Hygroscopic
Yes
Light Sensitive
Yes
Molecular Formula
C24H39N5O5
Percent Composition
C 60.36%, H 8.23%, N 14.66%, O 16.75%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
799268-47-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
477.597
Exact Mass
477.295
Synonyms
D-erythro-Sphingosine-N-NBD
References

Lee JY, Han SH, Park MH, Song IS, Choi MK, Yu E, Park CM, Kim HJ, Kim SH, Schuchman EH, Jin HK, Bae JS. N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer's disease. Nat Commun. 2020 May 12;11(1):2358. doi: 10.1038/s41467-020-16080-4. PMID: 32398649; PMCID: PMC7217877.

PubMed ID: 32398649

Nishino S, Yamashita H, Tamori M, Mashimo M, Yamagata K, Nakamura H, Murayama T. Translocation and activation of sphingosine kinase 1 by ceramide-1-phosphate. J Cell Biochem. 2019 Apr;120(4):5396-5408. doi: 10.1002/jcb.27818. Epub 2018 Nov 15.

PubMed ID: 30444039

Plöhn S, Edelmann B, Japtok L, He X, Hose M, Hansen W, Schuchman EH, Eckstein A, Berchner-Pfannschmidt U. CD40 Enhances Sphingolipids in Orbital Fibroblasts: Potential Role of Sphingosine-1-Phosphate in Inflammatory T-Cell Migration in Graves' Orbitopathy. Invest Ophthalmol Vis Sci. 2018 Nov 1;59(13):5391-5397. doi: 10.1167/iovs.18-25466.

PubMed ID: 30452592
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