N-P Serine PA | 800715
N-palmitoyl-serine phosphoric acid (ammonium salt)
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A range of 0.1-20 mM of N-palmitoyl serine phosphoric acid can be used for cell studies. Make a stock solution of 5 mM in DMSO and store at -20°C. Diluted N-palmitoyl serine phosphoric acid can be directly added to the study medium [Jan et al, 2003]. An et al. dissolved N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acid in 0.1 mL PBS containing 0.1 mg/mL human serum albumin before adding to cells [An et al, 1998]. In X. laevis studies, these LPA inhibitors were dissolved in DMSO at 1 mM and filtered through a 0.45 mM membrane filter before injection [Liliom et al, 1996].
- Molecular Formula
- Percent Composition
- C 49.88%, H 9.69%, N 9.18%, O 24.48%, P 6.77%
- 1 Years
- CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
- Molecular Weight
- Exact Mass
Jan, C.R., Lu, Y.C., Jiann, B.P., Chang, H.T., Wang, J.L., Chen, W.C., Huang, J.K. (2003) Novel effect of N-palmitoyl-L-serine phosphoric acid on cytosolic Ca2+ levels in human osteoblasts. Pharmacol Toxicol. 93:71-6. [PubMed]
Hooks, S.B., Ragan, S.P., Hopper, D.W., Hönemann, C.W., Durieux, M.E., Macdonald, T.L., Lynch, K.R. (1998) Characterization of a receptor subtype-selective lysophosphatidic acid mimetic. Mol Pharmacol. 53:188-94. [PubMed]
An, S., Bleu, T., Zheng, Y., Goetzl, E.J. (1998) Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization. Mol Pharmacol. 54:881-8. [PubMed]
Liliom, K., Bittman, R., Swords, B., Tigyi, G. (1996) N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids are selective competitive antagonists of the lysophosphatidic acid receptors. Mol Pharmacol. 50:616-23. [PubMed]
Bittman, R., Swords, B., Liliom, K., Tigyi, G. (1996) Inhibitors of lipid phosphatidate receptors: N-palmitoyl-serine and N-palmitoyl-tyrosine phosphoric acids. J Lipid Res. 37:391-8. [PubMed]