700270 | Murideoxycholic acid

5ß-cholanic acid-3α,6ß-diol


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Murideoxycholic acid

Murideoxycholic acid

5ß-cholanic acid-3α,6ß-diol

Murideoxycholic acid (MDCA/muricholic acid/murideoxycholate) belongs to a group of secondary bile acids (BAs). It is found as one of the major forms in mice and is present in low concentrations in humans. 

It is a 3α-hydroxy steroid that has hydroxyl groups at positions 3α and 6β. The compound is produced from α-muricholic acid and β-muricholic acid. The enzymes that catalyze the hydroxylation reactions, forming muricholates in mice, are the cytochrome P450 CYP2c70 enzymes.

MDCA is proven to prevent gallstone formation in hamsters on a lithogenic diet. Yet, it doesn’t resolve gallstones in dogs on a high cholesterol diet.

In humans, MDCA is absorbed and metabolized rapidly as an endogenous BA with an approximately 3.5 days half-life.

With exceptional purity and quality, Avanti Lipids Murideoxycholic acid is ready to take your research to success.

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C24H40O4

Percent Composition

C 73.43%, H 10.27%, O 16.30%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
668-49-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
392.580
Exact Mass
392.290