700240 | Nordeoxycholic acid

23-nor-5β-cholanoic acid-3α, 12α-diol


Powder

Size SKU Packaging Price
5mg 700240P-5mg 700240P-5mg 1 x 5mg $163.75
Base Price: ${originalprice|money}
Custom Packaging: (${concentration} @$4.00/ea. + $100) ${custompackagingtotal|money}
Packaging: ${concentration}
Item Total: ${totalprice|money}
(Sales Tax may apply)
Please select an option above.
${sku} - ${concentration}

Nordeoxycholic acid

Nordeoxycholic acid

23-nor-5β-cholanoic acid-3α, 12α-diol

Nordeoxycholic Acid also known as 23-Nor-Deoxycholic Acid (23-Nor-DCA) is a steroid human metabolite with higher serum levels in women compared to men.

It’s a relative of the bile acid (BA) norcholic acid and a 23-carbon derivative of deoxycholic acid (DCA). 

Norcholic acid is a minor BA found predominantly in human urine and meconium, while deoxycholic acid is one of the secondary BAs and an end product of the intestinal bacteria.

All BAs are important biomolecules, synthesized in the liver from cholesterol catabolism and responsible for the normal digestion and absorption of fats and other sterols. However, under certain pathological conditions, certain BAs can become prominent, and tend to show toxic effects on cells and tissues.

Levels of Norcholic acid, for instance, are increased in patients with cirrhosis and xanthomatosis - a metabolic disorder, characterized by mitochondrial enzyme sterol 27-hydrolase (CYP27A1) deficiency, that leads to progressive neurological symptoms.

As for the other parent compound of Nordeoxycholic Acid, DCA, it’s a BA with numerous effects in the human body, including emulsification of fats, preventing and dissolving gallstones, adipocytes destruction, and more.

As a BA, Nordeoxycholic Acid has similar effects, and it has also been found to decrease in models of rats on a high-fat diet, with a nonalcoholic fatty acid liver disease.

Additionally, Nordeoxycholic Acid is widely used as an internal standard for the quantification of bile acids.

Avanti’s Nordeoxycholic Acid is a high-quality bile acid for use in various types of bioanalyses research.

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C23H38O4

Percent Composition

C 72.98%, H 10.12%, O 16.91%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
53608-86-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
378.550
Exact Mass
373.280