Products

PhotoClick Cholesterol | 700147

Hex-5'-ynyl 3ß-hydroxy-6-diazirinyl-5α-cholan-24-oate

700147P

Powder

100 μg
$170.00
250 μg
$365.00

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PhotoClick Cholesterol is a clickable, photoreactive sterol probe for use in combination with quantitative mass spectrometry to globally map cholesterol-protein interactions directly in living cells. In addition to the UV-activatable cross-linking diazirine group that reacts with proteins, the sterol contains an alkyne group for incorporation of reporter and affinity tags through click-chemistry.
Molecular Formula
C30H46N2O3
Percent Composition
C 74.65%, H 9.61%, N 5.80%, O 9.94%
Purity
>99%
Stability
6 Months
Storage
-20°C
CAS Number
1485490-47-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
482.698
Exact Mass
482.351
Synonyms
hex-5-yn-1-yl 4-((3S,5S)-3-hydroxy-10,13-dimethyl-1,2,3,4,5,7,8,9,10,11,12,13,14,15,16,17-hexadecahydrospiro[cyclopenta[a]phenanthrene-6,3'-diazirin]-17-yl)pentanoate
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Hulce, J.J., A.B. Cognetta, M.J. Niphakis, S.E. Tully, and B.F. Cravatt. (2013). Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells. Nat Methods 10:259-64. [PubMed]