CholPC | 700123
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- Ceramide forms stable, fluid bilayers with cholesteryl phosphocholine, and this formulation has been shown to be more potent than solvent-delivered (DMSO) formulations of C6 Ceramide in inhibiting proliferation, inducing apoptosis, and disturbing calcium homeostasis.
CholPC forms bilayers (giant uni- and multilamellar vesicles, as well as extruded large unilamellar vesicles) with both ceramides and cholesterol. The extruded bilayers appear to be fluid, although highly ordered, even when the ceramide has an N-linked palmitoyl acyl chain.
- Molecular Formula
- Percent Composition
- C 69.65%, H 10.59%, N 2.54%, O 11.60%, P 5.61%
- 1 Years
- CAS Number
CAS Registry Number is a Registered Trademark of the American Chemical Society
- Molecular Weight
- Exact Mass
Complexation of C6-Ceramide with Cholesteryl Phosphocholine – A Potent Solvent-Free Ceramide Delivery Formulation for Cells in Culture (2013). Pramod Sukumaran , Max Lönnfors , Otto Långvik, Ilari Pulli, Kid Törnquist, J. Peter Slotte. [PLOS ONE]
Lonnfors, M., O. Langvik, A. Bjorkbom, and J.P. Slotte. (2013). Cholesteryl Phosphocholine - A Study on its Interactions with Ceramides and Other Membrane Lipids.Langmuir 29:2319-29.[PubMed]