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CholPC | 700123

cholesteryl phosphocholine

700123P

Powder

700123P-
25mg
$78.00
700123P-
500mg
$705.00

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Ceramide forms stable, fluid bilayers with cholesteryl phosphocholine, and this formulation has been shown to be more potent than solvent-delivered (DMSO) formulations of C6 Ceramide in inhibiting proliferation, inducing apoptosis, and disturbing calcium homeostasis.CholPC forms bilayers (giant uni- and multilamellar vesicles, as well as extruded large unilamellar vesicles) with both ceramides and cholesterol. The extruded bilayers appear to be fluid, although highly ordered, even when the ceramide has an N-linked palmitoyl acyl chain.
Molecular Formula
C32H58NO4P
Percent Composition
C 69.65%, H 10.59%, N 2.54%, O 11.60%, P 5.61%
Purity
>99%
Stability
1 Years
Storage
-20°C
CAS Number
65956-64-1
CAS Registry Number is a Registered Trademark of the American Chemical Society
Molecular Weight
551.781
Exact Mass
551.410
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Notes
GIF Graphics File. 
GIF Graphics File. 
MDL Molfile. 
CDX File. 
Fangming Xu, Haibo Wang, Jie Zhao, Xiangsheng Liu, Dandan Li, Chaojian Chen, and Jian Ji. (2014). Chiral Packing of Cholesteryl Group as an Effective Strategy To Get Low Molecular Weight Supramolecular Hydrogels in the Absence of Intermolecular Hydrogen Bond. Macromolecules, 2013, 46 (11), pp 4235–4246 [Link]Complexation of C6-Ceramide with Cholesteryl Phosphocholine – A Potent Solvent-Free Ceramide Delivery Formulation for Cells in Culture (2013). Pramod Sukumaran , Max Lönnfors , Otto Långvik, Ilari Pulli, Kid Törnquist, J. Peter Slotte. [PLOS ONE]Lonnfors, M., O. Langvik, A. Bjorkbom, and J.P. Slotte. (2013). Cholesteryl Phosphocholine - A Study on its Interactions with Ceramides and Other Membrane Lipids.Langmuir 29:2319-29.[PubMed]