700107 | Sitosterol (synthetic from plant sterol)

Sitosterol (synthetic from plant sterol)


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Size SKU Packaging Price
100mg 700107P-100mg 700107P-100mg 1 x 100mg $253.00
200mg 700107P-200mg 700107P-200mg 2 x 100mg $432.00
500mg 700107P-500mg 700107P-500mg 5 x 100mg $920.00
1g 700107P-1g 700107P-1g 1 x 1g $1,646.57
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Sitosterol (synthetic from plant sterol)

Sitosterol (synthetic from plant sterol)

Sitosterol (synthetic from plant sterol)

β-sitosterol is a phytosterol (plant sterol) found in a wide variety of plants such as pecans, saw palmetto, avocados, pumpkin seed, rice bran, wheat germ, and soybeans. Recently, sitosterol has been investigated as a substitute for cholesterol in lipid-based mRNA delivery systems. In 2020, it was reported that β-sitosterol-substituted lipid nanoparticle (LNPs) maintained comparable size and encapsulation but were considerably more effective at mRNA transfection than LNPs containing cholesterol (Patel, 2020). Purchase Avanti's sitosterol today to fuel your therapeutics delivery research. 

Hygroscopic
No
Light Sensitive
No
Molecular Formula

C29H50O

Percent Composition

C 83.99%, H 12.15%, O 3.86%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
Formula Weight
414.720
Exact Mass
414.390

Patel S, Ashwanikumar N, Robinson E, Xia Y, Mihai C, Griffith JP 3rd, Hou S, Esposito AA, Ketova T, Welsher K, Joyal JL, Almarsson Ö, Sahay G. Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA. Nat Commun. 2020 Feb 20;11(1):983. doi: 10.1038/s41467-020-14527-2. Erratum in: Nat Commun. 2020 Jul 6;11(1):3435. PMID: 32080183; PMCID: PMC7033178.