700087 | DHEA

Dehydroepiandrosterone


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DHEA

DHEA

Dehydroepiandrosterone

DHEA (dehydroepiandrosterone) is an endogenous steroid hormone secreted by the adrenal gland. DHEA serves as precursor to male and female sex hormones (androgens and estrogens).

Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C19H28O2
Percent Composition
C 79.12%, H 9.78%, O 11.09%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
53-43-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
288.424
Exact Mass
288.209
Synonyms
<p>DHEA3β-hydroxy-5-androsten-17-one5-androsten-3β-ol-17-onedehydroisoandrosteronetrans-dehydroandrosteronePrasterone</p>

Revilla G, Pons MP, Baila-Rueda L, García-León A, Santos D, Cenarro A, Magalhaes M, Blanco RM, Moral A, Ignacio Pérez J, Sabé G, González C, Fuste V, Lerma E, Faria MDS, de Leiva A, Corcoy R, Carles Escolà-Gil J, Mato E. Cholesterol and 27-hydroxycholesterol promote thyroid carcinoma aggressiveness. Sci Rep. 2019 Jul 16;9(1):10260. doi: 10.1038/s41598-019-46727-2.

PubMed ID: 31311983

Dias IHK, Ferreira R, Gruber F, Vitorino R, Rivas-Urbina A, Sanchez-Quesada JL, Vieira Silva J, Fardilha M, de Freitas V, Reis A. Sulfate-based lipids: Analysis of healthy human fluids and cell extracts. Chem Phys Lipids. 2019 Mar 22;221:53-64. doi: 10.1016/j.chemphyslip.2019.03.009. [Epub ahead of print]

PubMed ID: 30910732

Chung KF, Qin N, Androutsellis-Theotokis A, Bornstein SR, Ehrhart-Bornstein M. Effects of dehydroepiandrosterone on proliferation and differentiation of chromaffin progenitor cells. Mol Cell Endocrinol. 2011 Apr 10;336(1-2):141-8. doi: 10.1016/j.mce.2010.11.028. Epub 2010 Dec 2.

PubMed ID: 21130143

Dillon JS. Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders. Curr Drug Targets Inflamm Allergy. 2005 Jun;4(3):377-85.

PubMed ID: 16101547

Racchi M, Balduzzi C, Corsini E. Dehydroepiandrosterone (DHEA) and the aging brain: flipping a coin in the "fountain of youth". CNS Drug Rev. 2003 Spring;9(1):21-40.

PubMed ID: 12595910

Ebeling P, Koivisto VA. Physiological importance of dehydroepiandrosterone. Lancet. 1994 Jun 11;343(8911):1479-81.

PubMed ID: 7911183