700077 | FF-MAS

14-demethyl-14-dehydrolanosterol

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FF-MAS

FF-MAS

14-demethyl-14-dehydrolanosterol

Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in the cholesterol biosynthetic pathway present in all cells, and may represent the physiological signal that instructs the oocyte to reinitiate meiosis.

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C29H46O
Percent Composition
C 84.81%, H 11.29%, O 3.90%
Purity
>99%
Stability
1 Year
Storage Temperature
-80°C
CAS Number
64284-64-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
410.675
Exact Mass
410.355
Synonyms
4,4-dimethyl-5α-cholesta-8,14,24-trien-3ß-olfollicular fluid meiosis-activating sterol

Allimuthu D, Hubler Z, Najm FJ, Tang H, Bederman I, Seibel W, Tesar PJ, Adams DJ. Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP. Cell Chem Biol. 2019 Jan 31. pii: S2451-9456(19)30026-1. doi: 10.1016/j.chembiol.2019.01.004. [Epub ahead of print]

 PubMed ID: 30773481

Fakheri RJ, Javitt NB. Autoregulation of cholesterol synthesis: physiologic and pathophysiologic consequences. Steroids. 2011 Feb;76(3):211-5. doi: 10.1016/j.steroids.2010.10.003. Epub 2010 Oct 15.

 PubMed ID: 20951718