700071 | 24(R)-hydroxycholesterol

cholest-5-ene-3ß,24(R)-diol


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24(R)-hydroxycholesterol

24(R)-hydroxycholesterol

cholest-5-ene-3ß,24(R)-diol

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C27H46O2
Percent Composition
C 80.54%, H 11.51%, O 7.95%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
27460-26-0
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
402.653
Exact Mass
402.350
Synonyms
5-cholestene-3ß,24-diol
24-hydroxycholest-5-en-3-ol

Hutchinson SA, Lianto P, Moore JB, Hughes TA, Thorne JL. Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells. Int J Mol Sci. 2019 Jul 2;20(13). pii: E3241. doi: 10.3390/ijms20133241.

PubMed ID: 31269628

Tajima N, Xiaoyan L, Taniguchi M, Kato N. 24S-hydroxycholesterol alters activity of large-conductance Ca2+-dependent K+ (slo1 BK) channel through intercalation into plasma membrane. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May 25. pii: S1388-1981(19)30085-X. doi: 10.1016/j.bbalip.2019.05.010. [Epub ahead of print]

PubMed ID: 31136842

Becares N, Gage MC, Voisin M, Shrestha E, Martin-Gutierrez L, Liang N, Louie R, Pourcet B, Pello OM, Luong TV, Goñi S, Pichardo-Almarza C, Røberg-Larsen H, Diaz-Zuccarini V, Steffensen KR, O'Brien A, Garabedian MJ, Rombouts K, Treuter E, Pineda-Torra I. Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease. Cell Rep. 2019 Jan 22;26(4):984-995.e6. doi: 10.1016/j.celrep.2018.12.094.

PubMed ID: 30673619