700058 | 22(R)-hydroxycholesterol

cholest-5-ene-3ß,22(R)-diol


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1mg 700058P-1mg 700058P-1mg 1 x 1mg $113.50
5mg 700058P-5mg 700058P-5mg 1 x 5mg $403.95
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22(R)-hydroxycholesterol

22(R)-hydroxycholesterol

cholest-5-ene-3ß,22(R)-diol

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C27H46O2
Percent Composition
C 80.54%, H 11.51%, O 7.95%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
17954-98-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
402.653
Exact Mass
402.350
Synonyms
5-cholestene-3ß,22-diol
22-hydroxycholest-5-en-3-ol

Hassani-Nezhad-Gashti F, Salonurmi T, Hautajärvi H, Rysä J, Hakkola J, Hukkanen J. Pregnane X Receptor Activator Rifampin Increases Blood Pressure and Stimulates Plasma Renin Activity. Clin Pharmacol Ther. 2020 Apr 28. doi: 10.1002/cpt.1871. Epub ahead of print. PMID: 32344455.

PubMed ID: 32344455

Abrams ME, Johnson KA, Perelman SS, Zhang LS, Endapally S, Mar KB, Thompson BM, McDonald JG, Schoggins JW, Radhakrishnan A, Alto NM. Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol. Nat Microbiol. 2020 Apr 13. doi: 10.1038/s41564-020-0701-5. Epub ahead of print. PMID: 32284563.

PubMed ID: 32284563

Hutchinson SA, Lianto P, Roberg-Larsen H, Battaglia S, Hughes TA, Thorne JL. ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling. Nutrients. 2019 Nov 1;11(11). pii: E2618. doi: 10.3390/nu11112618.

PubMed ID: 31683867

Solheim S, Hutchinson SA, Lundanes E, Wilson SR, Thorne JL, Roberg-Larsen H. Fast liquid chromatography-mass spectrometry reveals side chain oxysterol heterogeneity in breast cancer tumour samples. J Steroid Biochem Mol Biol. 2019 Feb 16. pii: S0960-0760(18)30754-4. doi: 10.1016/j.jsbmb.2019.02.004. [Epub ahead of print]

PubMed ID: 30779932

Becares N, Gage MC, Voisin M, Shrestha E, Martin-Gutierrez L, Liang N, Louie R, Pourcet B, Pello OM, Luong TV, Goñi S, Pichardo-Almarza C, Røberg-Larsen H, Diaz-Zuccarini V, Steffensen KR, O'Brien A, Garabedian MJ, Rombouts K, Treuter E, Pineda-Torra I. Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease. Cell Rep. 2019 Jan 22;26(4):984-995.e6. doi: 10.1016/j.celrep.2018.12.094.

PubMed ID: 30673619