700034 | 7α-hydroxycholesterol

cholest-5-en-3ß,7α-diol


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5mg 700034P-5mg 700034P-5mg 1 x 5mg $167.20
10mg 700034P-10mg 700034P-10mg 1 x 10mg $262.40
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7α-hydroxycholesterol

7α-hydroxycholesterol

cholest-5-en-3ß,7α-diol

Hygroscopic
No
Light Sensitive
No
Molecular Formula
C27H46O2
Percent Composition
C 80.54%, H 11.51%, O 7.95%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
566-26-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
402.653
Exact Mass
402.350
Synonyms
cholest-5-ene-3b,7a-diol
110808

Abrams ME, Johnson KA, Perelman SS, Zhang LS, Endapally S, Mar KB, Thompson BM, McDonald JG, Schoggins JW, Radhakrishnan A, Alto NM. Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol. Nat Microbiol. 2020 Apr 13. doi: 10.1038/s41564-020-0701-5. Epub ahead of print. PMID: 32284563.

PubMed ID: 32284563

Yalcinkaya M, Kerksiek A, Gebert K, Annema W, Sibler R, Radosavljevic S, Luetjohann D, Rohrer L, von Eckardstein A. HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened. J Lipid Res. 2020 Jan 6:jlr.RA119000509. doi: 10.1194/jlr.RA119000509. Epub ahead of print. PMID: 31907205.

PubMed ID: 31907205

Rossin D, Barbosa-Pereira L, Iaia N, Testa G, Sottero B, Poli G, Zeppa G, Biasi F. A Dietary Mixture of Oxysterols Induces In Vitro Intestinal Inflammation through TLR2/4 Activation: The Protective Effect of Cocoa Bean Shells. Antioxidants (Basel). 2019 May 31;8(6). pii: E151. doi: 10.3390/antiox8060151.

PubMed ID: 31151323

Wnętrzak A, Chachaj-Brekiesz A, Janikowska-Sagan M, Dynarowicz-Latka P. Influence of 7α-hydroxycholesterol on sphingomyelin and sphingomyelin/phosphatidylcholine films - The Langmuir monolayer study complemented with theoretical calculations. Biochim Biophys Acta Biomembr. 2019 Apr 1;1861(4):861-870. doi: 10.1016/j.bbamem.2019.01.020. Epub 2019 Feb 1.

PubMed ID: 30716293

Wang X, Sun J, Zhao XE, Xu Y, Sun L, Zhu S, You J, Wang X. Stable isotope labeling derivatization coupled with magnetic dispersive solid phase extraction for the determination of hydroxyl-containing cholesterol and metabolites by in vivo microdialysis and ultra-high performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 2019 Feb 14. pii: S0021-9673(19)30151-7. doi: 10.1016/j.chroma.2019.02.021. [Epub ahead of print]

PubMed ID: 30797576

Anita Wnętrzak, Anna Chachaj-Brekiesz, Maria Janikowska-Sagan, Jose Luis Fidalgo Rodriguez, Jose Miñones Conde, Patrycja Dynarowicz-Latkaa. Crucial role of the hydroxyl group orientation in Langmuir monolayers organization–The case of 7-hydroxycholesterol epimers. Colloids and Surfaces A: Physiocochemical and Engineering Aspects. 2019 Feb 20;563:330-339. doi: 10.1016/j.colsurfa.2018.12.025